Search Results - "von Wilmsdorff, Martina"
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Gene expression of glutamate transporters SLC1A1, SLC1A3 and SLC1A6 in the cerebellar subregions of elderly schizophrenia patients and effects of antipsychotic treatment
Published in The world journal of biological psychiatry (01-09-2013)“…Abstract Objectives. The glutamatergic hypothesis of schizophrenia proposes alterations of excitatory amino acid transporters (solute carrier family, SLCs)…”
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Reduced oxytocin receptor gene expression and binding sites in different brain regions in schizophrenia: A post-mortem study
Published in Schizophrenia research (01-11-2016)“…Abstract Schizophrenia is a severe neuropsychiatric disorder with impairments in social cognition. Several brain regions have been implicated in social…”
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Effects of Aerobic Exercise on Metabolic Syndrome, Cardiorespiratory Fitness, and Symptoms in Schizophrenia Include Decreased Mortality
Published in Frontiers in psychiatry (21-12-2018)“…Schizophrenia is a severe psychiatric disorder with a lifetime prevalence of about 1%. People with schizophrenia have a 4-fold higher prevalence of metabolic…”
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Effects of haloperidol and clozapine on synapse-related gene expression in specific brain regions of male rats
Published in European archives of psychiatry and clinical neuroscience (01-09-2018)“…We investigated the effects of clozapine and haloperidol, drugs that are widely used in the treatment of schizophrenia, on gene expression in six cortical and…”
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Sex-dependent effects of long-term clozapine or haloperidol medication on red blood cells and liver iron metabolism in Sprague Dawley rats as a model of metabolic syndrome
Published in BMC pharmacology & toxicology (15-01-2022)“…Patients with liver diseases often have some form of anemia. Hematological dyscrasias are known side effects of antipsychotic drug medication and the…”
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Sex‐dependent alterations of dopamine receptor and glucose transporter density in rat hypothalamus under long‐term clozapine and haloperidol medication
Published in Brain and behavior (01-08-2020)“…Objective Sex‐dependent disturbances of peripheral glucose metabolism are known complications of antipsychotic drug treatment. The influence of long‐term…”
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Rates and predictors of remission in first-episode schizophrenia within 1 year of antipsychotic maintenance treatment. Results of a randomized controlled trial within the German Research Network on Schizophrenia
Published in Schizophrenia research (01-02-2014)“…Abstract Objective Full and sustained symptom remission is a major treatment objective after a first-episode in schizophrenia. Findings regarding differences…”
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8
Decreased reelin expression in the left prefrontal cortex (BA9) in chronic schizophrenia patients
Published in Neuropsychobiology (01-01-2012)“…Reelin is under epigenetic control and has been reported to be decreased in cortical regions in schizophrenia. To establish if expression of reelin is altered…”
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Increased d-amino acid oxidase expression in the bilateral hippocampal CA4 of schizophrenic patients: a post-mortem study
Published in Journal of Neural Transmission (01-12-2009)“…An important risk gene in schizophrenia is d- amino acid oxidase (DAAO). To establish if expression of DAAO is altered in cortical, hippocampal or thalamic…”
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10
Association between myelin basic protein expression and left entorhinal cortex pre-alpha cell layer disorganization in schizophrenia
Published in Brain research (16-11-2009)“…Abstract There is evidence for migrational disturbances in the entorhinal cortex (ERC) in schizophrenia that supports a neurodevelopmental origin of the…”
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The impact of antipsychotic drugs on food intake and body weight and on leptin levels in blood and hypothalamic ob-r leptin receptor expression in wistar rats
Published in Clinics (São Paulo, Brazil) (2010)“…The aim of our study was to investigate the impact of typical and atypical antipsychotic drugs on leptin concentration in blood and changes in the receptor…”
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Pharmacological long-term treatment strategies in first episode schizophrenia--study design and preliminary results of an ongoing RCT within the German Research Network on Schizophrenia
Published in European archives of psychiatry and clinical neuroscience (01-04-2004)“…In first-episode schizophrenia the advantage of new atypical neuroleptics compared to low-dose haloperidol as well as the indicated duration of neuroleptic…”
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Sex-dependent behavioral effects and morphological changes in the hippocampus after prenatal invasive interventions in rats: implications for animal models of schizophrenia
Published in Clinics (São Paulo, Brazil) (01-02-2010)“…Although schizophrenia affects both human genders, there are gender-dependent differences with respect to age of onset, clinical characteristics, course and…”
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Reversible Neutropenia during Treatment with Olanzapine: Three Case Reports
Published in The world journal of biological psychiatry (01-10-2004)“…Summary Olanzapine is an atypical antipsychotic with a low incidence of extrapyramidal-motoric side effects. Its chemical structure is related to clozapine,…”
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Post-mortem gene expression of calcium channels Cav1.2 and Cav1.3 in schizophrenia
Published in European archives of psychiatry and clinical neuroscience (01-10-2022)Get full text
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Predictors for symptom re-exacerbation after targeted stepwise drug discontinuation in first-episode schizophrenia: Results of the first-episode study within the German research network on schizophrenia
Published in Schizophrenia research (01-01-2016)“…After a first episode in schizophrenia guidelines recommend antipsychotic maintenance treatment (MT) for at least 1year. Recent RCTs on subsequent targeted…”
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Relapse Prevention in First-Episode Schizophrenia—Maintenance vs Intermittent Drug Treatment With Prodrome-Based Early Intervention: Results of a Randomized Controlled Trial Within the German Research Network on Schizophrenia
Published in The journal of clinical psychiatry (01-02-2011)“…After acute treatment of the first illness episode in schizophrenia, antipsychotic maintenance treatment is recommended for at least 1 year. Evidence for the…”
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Rates and predictors of remission in first-episode schizophrenia within 1year of antipsychotic maintenance treatment. Results of a randomized controlled trial within the German Research Network on Schizophrenia
Published in Schizophrenia research (01-02-2014)“…Full and sustained symptom remission is a major treatment objective after a first-episode in schizophrenia. Findings regarding differences in remission between…”
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19
Drug attitude as predictor for effectiveness in first-episode schizophrenia: Results of an open randomized trial (EUFEST)
Published in European neuropsychopharmacology (01-05-2010)“…Abstract Effectiveness has become more and more important as a comprehensive outcome measure for (long-term) treatment in schizophrenia. Early predictors to…”
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Proteomic Similarities Between Heterozygous Reeler Mice and Schizophrenia
Published in Biological psychiatry (1969) (15-09-2013)Get full text
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