Search Results - "von Rosenstiel, P."

Adjunctive brivaracetam for refractory partial-onset seizures: A randomized, controlled trial by FRENCH, J. A, COSTANTINI, C, BRODSKY, A, VON ROSENSTIEL, P

“…To explore efficacy and safety/tolerability of adjunctive brivaracetam (BRV), a novel, high-affinity synaptic vesicle protein 2A ligand, which also inhibits…”
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Exacerbation of Apoptosis in the Dentate Gyrus of the Aged Rat by Dexamethasone and the Protective Role of Corticosterone by Hassan, A.H.S., von Rosenstiel, P., Patchev, V.K., Holsboer, F., Almeida, O.F.X.

“…Glucocorticoid-induced cell loss in the dentate gyrus of rats of various ages was studied using the TUNEL procedure to detect apoptotic cells. A highly…”
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Relapses in patients treated with fingolimod after previous exposure to natalizumab by Comi, G, Gold, R, Dahlke, F, Sinha, A, von Rosenstiel, P, Tomic, D, Kappos, L

“…In post hoc analyses of an open-label, phase 3b study (FIRST), relapse rates during 4 months of fingolimod therapy were compared in patients with and without…”
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Five-year results from a phase 2 study of oral fingolimod in relapsing multiple sclerosis by Izquierdo, G, O’Connor, P, Montalban, X, von Rosenstiel, P, Cremer, M, de Vera, A, Sfikas, N, Francis, G, Radue, EW, Kappos, L

“…We present here results at 60 months (M), from the extension component of a phase 2, randomized, placebo-controlled, double-blind, six-month study evaluating…”
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Fingolimod first-dose effects in patients with relapsing multiple sclerosis concomitantly receiving selective serotonin-reuptake inhibitors by Bermel, R.A, Hashmonay, R, Meng, X, Randhawa, S, von Rosenstiel, P, Sfikas, N, Kantor, D

“…Abstract Selective serotonin-reuptake inhibitors (SSRIs), commonly administered for depression and anxiety in patients with multiple sclerosis, are associated…”
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Effect of prior treatment status and reasons for discontinuation on the efficacy and safety of fingolimod vs. interferon β-1a intramuscular: Subgroup analyses of the Trial Assessing Injectable Interferon vs. Fingolimod Oral in Relapsing–Remitting Multiple Sclerosis (TRANSFORMS) by Khatri, B.O, Pelletier, J, Kappos, L, Hartung, H.-P, Comi, G, Barkhof, F, von Rosenstiel, P, Meng, X, Grinspan, A, Hashmonay, R, Cohen, J.A

“…Abstract Background Fingolimod demonstrated superior efficacy compared with interferon β-1a intramuscular in relapsing multiple sclerosis. The impact of…”
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Plasticity of hippocampal corticosteroid receptors during aging in the rat by HASSAN, A. H. S., PATCHEV, V. K., VON ROSENSTIEL, P., HOLSBOER, F., ALMEIDA, O. F. X.

“…ABSTRACT Aging is commonly associated with dysregulation of the hypothalamo‐pituitary‐adrenal axis and cognitive impairment. On the basis of suggestions that…”
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Brivaracetam (UCB 34714) by von Rosenstiel, Philipp

“…Brivaracetam (UCB 34714) is chemically related to levetiracetam (LEV, Keppra®). It possesses a binding affinity for the synaptic vesicle protein 2A (SV2A)…”
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Oral Orexin Receptor 2 Agonist in Narcolepsy Type 1 by Dauvilliers, Yves, Mignot, Emmanuel, del Río Villegas, Rafael, Du, Yeting, Hanson, Elizabeth, Inoue, Yuichi, Kadali, Harisha, Koundourakis, Elena, Meyer, Seetha, Rogers, Raquel, Scammell, Thomas E., Sheikh, Sarah I., Swick, Todd, Szakács, Zoltan, von Rosenstiel, Philipp, Wu, Jingtao, Zeitz, Heidi, Murthy, N. Venkatesha, Plazzi, Giuseppe, von Hehn, Christian

“…In a randomized trial involving patients with narcolepsy, an oral orexin receptor 2 agonist reduced sleepiness and cataplexy but had liver toxic effects…”
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Assessment of Potential Risk of PML with Fingolimod in MS Treated for at Least 24 Months (P04.137) by Francis, G., Dahlke, F., Von Rosenstiel, P., Sfikas, N.

“…Abstract only…”
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SUSTAINED LOW RATE BRAIN VOLUME LOSS IN LONG TERM FINGOLIMOD TREATMENT by Silber, E, Radue, EW, Barkhof, F, Gottschalk, R, Zhang, Y, Cappiello, L, von Rosenstiel, P, Kappos, L

“…ObjectivesTo evaluate long-term Brain Volume Loss (BVL) in patients who received fingolimod 0.5 mg or placebo in the FREEDOMS or FREEDOMS-2, and LONGTERMS…”
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24-MONTH ANALYSIS FROM PRIME, A PHASE 1B STUDY IN PATIENTS WITH PRODROMAL/MILD ALZHEIMER’S DISEASE by von Rosenstiel, P, Gheuens, S, O’Gorman, J, Chiao, P, Hock, C, Nitsch, R, Budd Haeberlein, S, Sandrock, A

“…PRIME is an ongoing Phase 1b study evaluating safety, tolerability, and PK/PD of aducanumab in patients (aged 50–90; positive amyloid PET scan) with…”
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Cardiac Safety of Fingolimod 0.5 mg during the First Dose Observation in 4-Month, Open-Label, Multi-Center FIRST Study in Patients with Relapsing MS (S41.003) by Comi, G., Kappos, L., Palace, J., Gottschalk, R., Bijarnia, M., Keil, A., Tomic, D., von Rosenstiel, P., Gold, R.

“…Abstract only…”
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Fingolimod (FTY720) oral for the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): Study design of the phase 3 FORCIDP trial by Hughes, R., Dalakas, M., Latov, N., Léger, J.-M., Merkies, I., Nobile-Orazio, E., Agoropoulou, C., Häring, D.A., Zhang-Auberson, L., von Rosenstiel, P., Hartung, H.-P.

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Multinational Gilenya  (Fingolimod) Pregnancy Exposure Registry in Multiple Sclerosis: Study Design (P06.189) by Geissbuhler, Y., Butzkueven, H., Hernandez-Diaz, S., Koren, G., MacDonald, T., Tilson, H., Starzyk, K., Plana, E., Cremer, M., von Rosenstiel, P., Hellwig, K.

“…Abstract only…”
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F ingolimod (FTY720) or al for the treatment of chronic inflammatory demyelinating polyradiculoneuropathy ( CIDP ): Study design of the phase 3 FORCIDP trial by Hughes, R, Dalakas, M, Latov, N, Léger, J.-M, Merkies, I, Nobile-Orazio, E, Agoropoulou, C, Häring, D.A, Zhang-Auberson, L, von Rosenstiel, P, Hartung, H.-P

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The prototypic mineralocorticoid receptor agonist aldosterone influences neurogenesis in the dentate gyrus of the adrenalectomized rat by Fischer, Anja K, von Rosenstiel, Philipp, Fuchs, Eberhard, Goula, Daniel, Almeida, Osborne F.X, Czéh, Boldizsár

“…Glucocorticoid receptor activation inhibits granule cell proliferation in the hippocampus, but little is known about the role of mineralocorticoid receptors in…”
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Exacerbation of apoptosis in the dentate gyrus of the aged rat by dexamethason and the protective role of corticosterone by HASSAN, A. H. S, VON ROSENSTIEL, P, PATCHEV, V. K, HOLSBOER, F, ALMEIDA, O. F. X

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Further development of microarea analysis techniques for determining nitrogen in steels by BAUMGARTL, S, BÜCHNER, A. R, VON ROSENSTIEL, P, SCHALKOORD, D, SCHAUF, E, SCHWAAB, P, VETTERS, H, KARDUCK, P, BURCHARD, W.-G, DUDEK, H.-J, HAEUSSLER, E. N, HANTSCHE, H, LIPHARDT, M, PRIES, H, REHBACH, W

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Contribution to R. Mitsche's, E. Plöckinger's and A. Kulmburg's lecture, "The distribution of alloy elements in cast iron with nodular graphite and the effect of various heat treatments on this distribution" by von Rosenstiel, A P

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