Search Results - "von Nieciecki, A."
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Pharmacokinetics and metabolism of the anti-oestrogen droloxifene in female human subjects
Published in Xenobiotica (01-08-2002)“…1. Single oral doses of a solution formulation of 14 C-droloxifene citrate (141 mg) appeared to be rapidly and well absorbed in four post-menopausal female…”
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Pharmacokinetic characteristics of a new liquid sustained-release formulation of theophylline designed for the elderly and children: microcaps as sachet
Published in International journal of clinical pharmacology and therapeutics (01-12-1996)“…A new sustained-release theophylline formulation was especially designed for the elderly and children. Microcapsules of theophylline, administered as a…”
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3
Urinary Excretion and Metabolism of Arbutin after Oral Administration of Arctostaphylos uvae ursi Extract as Film-Coated Tablets and Aqueous Solution in Healthy Humans
Published in Journal of clinical pharmacology (01-08-2002)“…Bearberry leaves and preparations made from them are traditionally used for urinary tract infections. The urinary excretion of arbutin metabolites was examined…”
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Relative bioavailability of diclofenac after a single administration of a new multiple-unit formulation of enteric-coated pellets
Published in Arzneimittel-Forschung (2001)“…The relative bioavailability of diclofenac (CAS 15307-86-5) was investigated after a single administration of a multiple-unit formulation containing 75 mg…”
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Pharmacokinetics of nilvadipine
Published in Journal of cardiovascular pharmacology (1992)“…Nilvadipine is absorbed rapidly and completely and its absolute bioavailability is about 14-19% because of its high first-pass metabolism. Maximum plasma…”
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Requirements for product quality of theophylline sustained-release preparations
Published in Arzneimittel-Forschung (01-05-1998)“…In consideration of the narrow therapeutic range and the pharmacology of theophylline (CAS 58-55-9), the pharmaceutic quality of sustained release theophylline…”
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Pharmacokinetics of a new fluid theophylline sustained-release drug form. Microcapsules in a sachet
Published in Arzneimittel-Forschung (01-05-1998)“…A new sustained release theophylline (CAS 58-55-9) formulation was especially designed for the elderly and children. Microcapsules of theophylline,…”
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8
Pharmacokinetics of theophylline in sustained-release formulation in young asthmatics
Published in Arzneimittel-Forschung (01-05-1998)“…Pharmacokinetics of two theophylline (CAS 58-55-9) sustained release preparations (T: Bronchoretard Capsules/R: Capsule formulation from the US market) were…”
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9
Pharmacokinetics of a theophylline sustained-release formulation after single and twice daily dosage
Published in Arzneimittel-Forschung (01-05-1998)“…Sustained release theophylline (CAS 58-55-9) preparations may be dosed once or alternatively twice-a-day, depending on the intention of a theophylline therapy…”
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10
In vivo verification of in vitro release specifications of a theophylline sustained-release preparation
Published in Arzneimittel-Forschung (01-05-1998)“…Especially in drugs with a narrow therapeutic range, "within product bioequivalence" i.e. "batch-to-batch bioequivalence" should be scrutinized. Therefore,…”
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Biological availability of gastric juice-resistant coated diclofenac preparations. 1. Bioavailability study following a single administration of a multiple-unit formulation in comparison with a single-unit formulation
Published in Arzneimittel-Forschung (01-11-1993)“…Bioavailability Study of Enteric Coated Diclofenac Formulations/1st Communication: Bioavailability study following single-dose administration of a…”
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The effect of bile secretion on the pharmacokinetics of a theophylline sustained-release preparation
Published in Arzneimittel-Forschung (01-05-1998)“…Bile excretion changes the physiological milieu of the duodenum, possibly resulting in enhanced absorption of a drug due to increased solubilisation. This…”
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14
The effect of different variables on the in vitro dissolution of a theophylline sustained-release preparation
Published in Arzneimittel-Forschung (01-05-1998)“…In vitro dissolution studies are valuable tools to judge quality and stability of sustained release dosage forms and are often utilised to predict the in vivo…”
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Pharmacokinetics and bioavailability of tamoxifen in postmenopausal healthy women
Published in Arzneimittel-Forschung (01-04-1996)“…A randomised cross-over study in 24 postmenopausal women was selected to establish bioequivalence of two tamoxifen (CAS 10540-29-1) formulations. In addition,…”
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Effect of gallbladder contraction induced cholagogia on the pharmacokinetic profile of a sustained-release theophylline formulation
Published in Arzneimittel-Forschung (01-12-1996)“…Bile excretion might change the physiological milieu of the duodenum resulting in enhanced absorption of a drug due to increased solubilisation. This possible…”
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