Search Results - "von Martels, Julius Z. H."

Increased fecal calprotectin levels in Crohn's disease correlate with elevated serum Th1- and Th17-associated cytokines by Bourgonje, Arno R, von Martels, Julius Z H, de Vos, Paul, Faber, Klaas Nico, Dijkstra, Gerard

“…Patient-reported symptoms and endoscopic disease activity do not correlate well in Crohn's disease (CD). This warrants the need for reliable biomarkers to…”
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Crohn's Disease in Clinical Remission Is Marked by Systemic Oxidative Stress by Bourgonje, Arno R, von Martels, Julius Z H, Bulthuis, Marian L C, van Londen, Marco, Faber, Klaas Nico, Dijkstra, Gerard, van Goor, Harry

“…Crohn's disease (CD) is characterized by chronic and relapsing inflammation of the gastro-intestinal tract. It is assumed that oxidative stress contributes to…”
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Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genes by Bradford, Stephen T., Nair, Shalima S., Statham, Aaron L., van Dijk, Susan J., Peters, Timothy J., Anwar, Firoz, French, Hugh J., von Martels, Julius Z. H., Sutcliffe, Brodie, Maddugoda, Madhavi P., Peranec, Michelle, Varinli, Hilal, Arnoldy, Rosanna, Buckley, Michael, Ross, Jason P., Zotenko, Elena, Song, Jenny Z., Stirzaker, Clare, Bauer, Denis C., Qu, Wenjia, Swarbrick, Michael M., Lutgers, Helen L., Lord, Reginald V., Samaras, Katherine, Molloy, Peter L., Clark, Susan J.

“…Adipocytes support key metabolic and endocrine functions of adipose tissue. Lipid is stored in two major classes of depots, namely visceral adipose (VA) and…”
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Inulin-grown Faecalibacterium prausnitzii cross-feeds fructose to the human intestinal epithelium by Fagundes, Raphael R., Bourgonje, Arno R., Saeed, Ali, Vich Vila, Arnau, Plomp, Niels, Blokzijl, Tjasso, Sadaghian Sadabad, Mehdi, von Martels, Julius Z. H., van Leeuwen, Sander S., Weersma, Rinse K., Dijkstra, Gerard, Harmsen, Hermie J. M., Faber, Klaas Nico

“…Many chronic diseases are associated with decreased abundance of the gut commensal Faecalibacterium prausnitzii. This strict anaerobe can grow on dietary…”
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Assessing intestinal permeability in Crohn's disease patients using orally administered 52Cr-EDTA by von Martels, Julius Z H, Bourgonje, Arno R, Harmsen, Hermie J M, Faber, Klaas Nico, Dijkstra, Gerard

“…Intestinal permeability can be assessed by monitoring renal excretion of orally administered radioactively 51Cr-labeled ethylenediaminetetraacetic acid…”
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A Combined Set of Four Serum Inflammatory Biomarkers Reliably Predicts Endoscopic Disease Activity in Inflammatory Bowel Disease by Bourgonje, Arno R., von Martels, Julius Z. H., Gabriëls, Ruben Y., Blokzijl, Tjasso, Buist-Homan, Manon, Heegsma, Janette, Jansen, Bernadien H., van Dullemen, Hendrik M., Festen, Eleonora A. M., ter Steege, Rinze W. F., Visschedijk, Marijn C., Weersma, Rinse K., de Vos, Paul, Faber, Klaas Nico, Dijkstra, Gerard

“…Introduction: Blood C-reactive protein (CRP) and fecal calprotectin levels are routinely measured as surrogate markers of disease activity in Inflammatory…”
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Mucosal Eosinophil Abundance in Non-Inflamed Colonic Tissue Is Associated with Response to Vedolizumab Induction Therapy in Inflammatory Bowel Disease by Gabriëls, Ruben Y, Bourgonje, Arno R, von Martels, Julius Z H, Blokzijl, Tjasso, Weersma, Rinse K, Galinsky, Kevin, Juarez, Julius, Faber, Klaas Nico, Kats-Ugurlu, Gursah, Dijkstra, Gerard

“…Vedolizumab is used as a treatment for patients with inflammatory bowel disease (IBD), but induction therapy leads to clinical response and remission in…”
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The role of gut microbiota in health and disease: In vitro modeling of host-microbe interactions at the aerobe-anaerobe interphase of the human gut by von Martels, Julius Z.H., Sadaghian Sadabad, Mehdi, Bourgonje, Arno R., Blokzijl, Tjasso, Dijkstra, Gerard, Faber, Klaas Nico, Harmsen, Hermie J.M.

“…The microbiota of the gut has many crucial functions in human health. Dysbiosis of the microbiota has been correlated to a large and still increasing number of…”
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Riboflavin Supplementation Promotes Butyrate Production in the Absence of Gross Compositional Changes in the Gut Microbiota by Liu, Lei, Sadaghian Sadabad, Mehdi, Gabarrini, Giorgio, Lisotto, Paola, von Martels, Julius Z H, Wardill, Hannah R, Dijkstra, Gerard, Steinert, Robert E, Harmsen, Hermie J M

“…We performed a randomized, placebo-controlled trial, RIBOGUT, to study the effect of 2 weeks supplementation with either 50 or 100 mg/d of riboflavin on (i)…”
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The effect of riboflavin supplementation on the systemic redox status in healthy volunteers: A post-hoc analysis of the RIBOGUT trial by Bourgonje, Arno R., Otten, Antonius T., Sadaghian Sadabad, Mehdi, von Martels, Julius Z.H., Bulthuis, Marian L.C., Faber, Klaas Nico, van Goor, Harry, Dijkstra, Gerard, Harmsen, Hermie J.M.

“…Riboflavin is a redox-active vitamin that plays a pivotal role in human energy metabolism. Riboflavin may have beneficial health effects by increasing…”
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Riboflavin Supplementation in Patients with Crohn’s Disease [the RISE-UP study] by von Martels, Julius Z H, Bourgonje, Arno R, Klaassen, Marjolein A Y, Alkhalifah, Hassan A A, Sadaghian Sadabad, Mehdi, Vich Vila, Arnau, Gacesa, Ranko, Gabriëls, Ruben Y, Steinert, Robert E, Jansen, Bernadien H, Bulthuis, Marian L C, van Dullemen, Hendrik M, Visschedijk, Marijn C, Festen, Eleonora A M, Weersma, Rinse K, de Vos, Paul, van Goor, Harry, Faber, Klaas Nico, Harmsen, Hermie J M, Dijkstra, Gerard

“…Abstract Background and Aims Crohn’s disease [CD] is characterised by chronic intestinal inflammation and dysbiosis in the gut. Riboflavin [vitamin B2] has…”
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Pseudolithiasis after recent use of ceftriaxone: an unexpected diagnosis in a child with abdominal pain by von Martels, Julius Z.H., MD, Van de Meeberg, Evelien K., MD, Holman, Mirjam, MD, Ligtenberg, Jack J.M., MD, PhD, ter Maaten, Jan C., MD, PhD

“…[...]an insoluble calcium-ceftriaxone complex is formed. [...]it is known that ceftriaxone therapy in children can cause the side effect of sonographic biliary…”
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A simple coculture system shows mutualism between anaerobic faecalibacteria and epithelial Caco-2 cells by Sadaghian Sadabad, Mehdi, von Martels, Julius Z. H., Khan, Muhammed Tanweer, Blokzijl, Tjasso, Paglia, Giuseppe, Dijkstra, Gerard, Harmsen, Hermie J. M., Faber, Klaas Nico

“…Most gut bacteria are obligate anaerobes and are important for human health. However, little mechanistic insight is available on the health benefits of…”
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Assessing intestinal permeability in Crohn's disease patients using orally administered .sup.52Cr-EDTA by von Martels, Julius Z. H, Bourgonje, Arno R, Harmsen, Hermie J. M, Faber, Klaas Nico, Dijkstra, Gerard

“…Background Intestinal permeability can be assessed by monitoring renal excretion of orally administered radioactively .sup.51 Cr-labeled…”
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