Search Results - "von Luettichau, Irene"

Low incidence of symptomatic osteonecrosis after allogeneic HSCT in children with high‐risk or relapsed ALL – results of the ALL‐SCT 2003 trial by Kuhlen, Michaela, Bader, Peter, Sauer, Martin, Albert, Michael H., Gruhn, Bernd, Güngör, Tayfun, Kropshofer, Gabriele, Lang, Peter, Lawitschka, Anita, Metzler, Markus, Pentek, Falk, Rossig, Claudia, Schlegel, Paul G., Schrappe, Martin, Schrum, Johanna, Schulz, Ansgar, Schwinger, Wolfgang, Stackelberg, Arend, Strahm, Brigitte, Suttorp, Meinolf, Luettichau, Irene Teichert‐von, Wößmann, Wilhelm, Borkhardt, Arndt, Meisel, Roland, Poetschger, Ulrike, Glogova, Evgenia, Peters, Christina

“…Summary Osteonecrosis (ON) was prospectively assessed in 557 children and adolescents in the Berlin‐Frankfurt‐Münster Stem Cell Transplantation in children…”
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Children and Adults with Refractory Acute Graft-versus-Host Disease Respond to Treatment with the Mesenchymal Stromal Cell Preparation "MSC-FFM"-Outcome Report of 92 Patients by Bonig, Halvard, Kuçi, Zyrafete, Kuçi, Selim, Bakhtiar, Shahrzad, Basu, Oliver, Bug, Gesine, Dennis, Mike, Greil, Johann, Barta, Aniko, Kállay, Krisztián M, Lang, Peter, Lucchini, Giovanna, Pol, Raj, Schulz, Ansgar, Sykora, Karl-Walter, Teichert von Luettichau, Irene, Herter-Sprie, Grit, Ashab Uddin, Mohammad, Jenkin, Phil, Alsultan, Abdulrahman, Buechner, Jochen, Stein, Jerry, Kelemen, Agnes, Jarisch, Andrea, Soerensen, Jan, Salzmann-Manrique, Emilia, Hutter, Martin, Schäfer, Richard, Seifried, Erhard, Paneesha, Shankara, Novitzky-Basso, Igor, Gefen, Aharon, Nevo, Neta, Beutel, Gernot, Schlegel, Paul-Gerhardt, Klingebiel, Thomas, Bader, Peter

“…(1) Background: Refractory acute graft-versus-host disease (R-aGvHD) remains a leading cause of death after allogeneic stem cell transplantation. Survival…”
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Genome‐wide analysis of somatic copy number alterations and chromosomal breakages in osteosarcoma by Smida, Jan, Xu, Hongen, Zhang, Yanping, Baumhoer, Daniel, Ribi, Sebastian, Kovac, Michal, von Luettichau, Irene, Bielack, Stefan, O'Leary, Valerie B., Leib‐Mösch, Christine, Frishman, Dmitrij, Nathrath, Michaela

“…Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. It is characterized by highly complex karyotypes with structural…”
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Effective treatment of steroid and therapy-refractory acute graft-versus-host disease with a novel mesenchymal stromal cell product (MSC-FFM) by Bader, Peter, Kuçi, Zyrafete, Bakhtiar, Shahrzad, Basu, Oliver, Bug, Gesine, Dennis, Michael, Greil, Johann, Barta, Aniko, Kállay, Krisztián M., Lang, Peter, Lucchini, Giovanna, Pol, Raj, Schulz, Ansgar, Sykora, Karl-Walter, von Luettichau, Irene, Herter-Sprie, Grit, Uddin, Mohammad Ashab, Jenkin, Phil, Alsultan, Abdulrahman, Buechner, Jochen, Stein, Jerry, Kelemen, Agnes, Jarisch, Andrea, Soerensen, Jan, Salzmann-Manrique, Emilia, Hutter, Martin, Schäfer, Richard, Seifried, Erhard, Klingebiel, Thomas, Bonig, Halvard, Kuçi, Selim

“…The inability to generate mesenchymal stromal cells (MSCs) of consistent potency likely is responsible for inconsistent clinical outcomes of patients with…”
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Osteosarcoma and causes of death: A report of 1520 deceased patients from the Cooperative Osteosarcoma Study Group (COSS) by Bielack, Stefan S., Blattmann, Claudia, Borkhardt, Arndt, Csóka, Monika, Hassenpflug, Wolf, Kabíčková, Edita, Kager, Leo, Kessler, Thorsten, Kratz, Christian, Kühne, Thomas, Kevric, Matthias, Lehrnbecher, Thomas, Mayer-Steinacker, Regine, Mettmann, Vanessa, Metzler, Markus, Reichardt, Peter, Rossig, Claudia, Sorg, Benjamin, von Luettichau, Irene, Windhager, Reinhard, Hecker-Nolting, Stefanie

“…Most aspects of osteosarcoma have been addressed in detail, but there is no comprehensive analysis of deceased patients and causes of death. The database of…”
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Analysis of self‐reported activities of daily living, motor performance and physical activity among children and adolescents with cancer: Baseline data from a randomised controlled trial assessed shortly after diagnosis of leukaemia or non‐Hodgkin lymphoma by Gaser, Dominik, Peters, Christiane, Götte, Miriam, Oberhoffer‐Fritz, Renate, Feuchtinger, Tobias, Schmid, Irene, Luettichau, Irene, Kesting, Sabine

“…Objective Cancer diagnosis, treatment side effects and physical inactivity can lead to reduced muscle strength. Patients undergoing acute treatment experience…”
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A Bout of High-Intensity Interval Training (HIIT) in Children and Adolescents during Acute Cancer Treatment-A Pilot Feasibility Study by Kesting, Sabine, Weeber, Peter, Schönfelder, Martin, Pfluger, Anja, Wackerhage, Henning, von Luettichau, Irene

“…Low- and moderate-intensity exercise is safe and feasible during childhood cancer treatment. The feasibility of a bout of high-intensity interval training…”
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EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation by Richter, Günther H.S, Plehm, Stephanie, Fasan, Annette, Rössler, Sabine, Unland, Rebekka, Bennani-Baiti, Idriss M, Hotfilder, Marc, Löwel, Diana, von Luettichau, Irene, Mossbrugger, Ilona, Quintanilla-Martinez, Leticia, Kovar, Heinrich, Staege, Martin S, Müller-Tidow, Carsten, Burdach, Stefan

“…Ewing tumors (ET) are highly malignant, localized in bone or soft tissue, and are molecularly defined by ews/ets translocations. DNA microarray analysis…”
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Multipotent Mesenchymal Stem Cells Acquire a Lymphendothelial Phenotype and Enhance Lymphatic Regeneration In Vivo by CONRAD, Claudius, NIESS, Hanno, HUSS, Ralf, HUBER, Stephan, VON LUETTICHAU, Irene, NELSON, Peter J, OTT, Harald C, JAUCH, Karl-Walter, BRUNS, Christiane J

“…The importance and therapeutic value of stem cells in lymphangiogenesis are poorly understood. We evaluated the potential of human and murine mesenchymal stem…”
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Human-Level Differentiation of Medulloblastoma from Pilocytic Astrocytoma: A Real-World Multicenter Pilot Study by Wiestler, Benedikt, Bison, Brigitte, Behrens, Lars, Tüchert, Stefanie, Metz, Marie, Griessmair, Michael, Jakob, Marcus, Schlegel, Paul-Gerhardt, Binder, Vera, von Luettichau, Irene, Metzler, Markus, Johann, Pascal, Hau, Peter, Frühwald, Michael

“…Medulloblastoma and pilocytic astrocytoma are the two most common pediatric brain tumors with overlapping imaging features. In this proof-of-concept study, we…”
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Correlation of Transcriptomics and FDG-PET SUVmax Indicates Reciprocal Expression of Stemness-Related Transcription Factor and Neuropeptide Signaling Pathways in Glucose Metabolism of Ewing Sarcoma by Prexler, Carolin, Knape, Marie Sophie, Erlewein-Schweizer, Janina, Roll, Wolfgang, Specht, Katja, Woertler, Klaus, Weichert, Wilko, von Luettichau, Irene, Rossig, Claudia, Hauer, Julia, Richter, Guenther H S, Weber, Wolfgang, Burdach, Stefan

“…In Ewing sarcoma (EwS), long-term treatment effects and poor survival rates for relapsed or metastatic cases require individualization of therapy and the…”
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Availability and adaption of exercise programs in pediatric oncology during the COVID-19 pandemic and beyond: a nationwide follow-up survey of providers in Germany by Kesting, Sabine, Gaser, Dominik, Queisser, Jennifer, Götte, Miriam, von Luettichau, Irene, Peters, Christiane, Oberhoffer-Fritz, Renate, Gauß, Gabriele

“…The COVID-19 pandemic has presented major challenges to clinical practice and delivery of care programs throughout all health care systems. Exercise programs,…”
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Exercise as a Potential Intervention to Modulate Cancer Outcomes in Children and Adults? by Kesting, Sabine, Weeber, Peter, Schönfelder, Martin, Renz, Bernhard W, Wackerhage, Henning, von Luettichau, Irene

“…Exercise is recommended for the healthy population as it increases fitness and prevents diseases. Moreover, exercise is also applied as an adjunct therapy for…”
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Short-Term Consequences of Pediatric Anti-cancer Treatment Regarding Blood Pressure, Motor Performance, Physical Activity and Reintegration Into Sports Structures by Keiser, Tina, Gaser, Dominik, Peters, Christiane, Oberhoffer-Fritz, Renate, Kesting, Sabine, von Luettichau, Irene

“…Background: Cardiovascular diseases in childhood cancer survivors are known late sequelae following treatment. Arterial stiffness, pulse wave velocity (PWV)…”
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No Improvement of Survival for Alveolar Rhabdomyosarcoma Patients After HLA-Matched Versus -Mismatched Allogeneic Hematopoietic Stem Cell Transplantation Compared to Standard-of-Care Therapy by Schober, Sebastian Johannes, Hallmen, Erika, Reßle, Florian, Gassmann, Hendrik, Prexler, Carolin, Wawer, Angela, von Luettichau, Irene, Ladenstein, Ruth, Kazanowska, Bernarda, Ljungman, Gustaf, Niggli, Felix, Lohi, Olli, Hauer, Julia, Gruhn, Bernd, Klingebiel, Thomas, Bader, Peter, Burdach, Stefan, Lang, Peter, Sparber-Sauer, Monika, Koscielniak, Ewa, Thiel, Uwe

“…Patients with stage IV alveolar rhabdomyosarcoma (RMA) have a 5-year-survival rate not exceeding 30%. Here, we assess the role of allogeneic hematopoietic stem…”
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Allogeneic hematopoietic stem cell transplantation from unrelated donors is associated with higher infection rates in children with acute lymphoblastic leukemia—A prospective international multicenter trial on behalf of the BFM‐SG and the EBMT‐PDWP by Pichler, Herbert, Lawitschka, Anita, Glogova, Evgenia, Willasch, Andre M., Luettichau, Irene, Lehrnbecher, Thomas, Matthes‐Martin, Susanne, Lang, Peter, Bader, Peter, Sykora, Karl W., Schrum, Johanna, Kremens, Bernhard, Ehlert, Karoline, Albert, Michael H., Kuhlen, Michaela, Meisel, Roland, Guengoer, Tayfun, Strahm, Brigitte, Gruhn, Bernd, Schulz, Ansgar, Woessmann, Wilhelm, Poetschger, Ulrike, Peters, Christina

“…Severe infections (SI) significantly impact on non‐relapse mortality after hematopoietic stem cell transplantation (HSCT). We assessed 432 children and…”
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Effects of strength exercise interventions on activities of daily living, motor performance, and physical activity in children and adolescents with leukemia or non-Hodgkin lymphoma: Results from the randomized controlled ActiveADL Study by Gaser, Dominik, Peters, Christiane, Oberhoffer-Fritz, Renate, Götte, Miriam, Feuchtinger, Tobias, Schmid, Irene, Haller, Bernhard, von Luettichau, Irene, Kesting, Sabine

“…Objectives Pediatric patients with cancer experience impairments in muscle strength and physical activity (PA) that may reduce autonomy during hospitalization…”
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Strong expression of CXCL12 is associated with a favorable outcome in osteosarcoma by Baumhoer, Daniel, Smida, Jan, Zillmer, Stephanie, Rosemann, Michael, Atkinson, Michael J, Nelson, Peter J, Jundt, Gernot, Luettichau, Irene von, Nathrath, Michaela

“…Hematogenous spread determines the outcome of osteosarcoma (OS) patients, but the pathogenesis of developing metastatic disease is still unclear. Chemokines…”
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Improved 6‐year overall survival in AT/RT – results of the registry study Rhabdoid 2007 by Bartelheim, Kerstin, Nemes, Karolina, Seeringer, Angela, Kerl, Kornelius, Buechner, Jochen, Boos, Joachim, Graf, Norbert, Dürken, Matthias, Gerss, Joachim, Hasselblatt, Martin, Kortmann, Rolf‐Dieter, Teichert von Luettichau, Irene, Nagel, Inga, Nygaard, Randi, Oyen, Florian, Quiroga, Eduardo, Schlegel, Paul‐Gerhardt, Schmid, Irene, Schneppenheim, Reinhard, Siebert, Reiner, Solano‐Paez, Palma, Timmermann, Beate, Warmuth‐Metz, Monika, Frühwald, Michael Christoph

“…Atypical teratoid rhabdoid tumors (AT/RT) are characterized by mutations and subsequent inactivation of SMARCB1 (INI1, hSNF5), a predilection for very young…”
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Transcriptome based individualized therapy of refractory pediatric sarcomas: feasibility, tolerability and efficacy by Weidenbusch, Bushra, Richter, Günther H S, Kesper, Marie Sophie, Guggemoos, Monika, Gall, Katja, Prexler, Carolin, Kazantsev, Ilya, Sipol, Alexandra, Lindner, Lars, Nathrath, Michaela, Witt, Olaf, Specht, Katja, Beitinger, Frigga, Knebel, Carolin, Hosie, Stuart, von Eisenhardt-Rothe, Rüdiger, Weichert, Wilko, Luettichau, Irene Teichert-von, Burdach, Stefan

“…Survival rates of pediatric sarcoma patients stagnated during the last two decades, especially in adolescents and young adults (AYAs). Targeted therapies offer…”
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