Search Results - "von Lieres, E."

Model-integrated process development demonstrated on the optimization of a robotic cation exchange step by Osberghaus, A., Drechsel, K., Hansen, S., Hepbildikler, S.K., Nath, S., Haindl, M., von Lieres, E., Hubbuch, J.

“…A new concept for chromatography process development based on high-through put data and mechanistic modeling will be presented in this paper. The concept is…”
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High Throughput Screening of Chromatographic Phases for Rapid Process Development by Bensch, M., Schulze Wierling, P., von Lieres, E., Hubbuch, J.

“…The necessity of being “first on the market” paired with the need to cut production costs highlights the need for strategies and techniques allowing a fast…”
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Determination of parameters for the steric mass action model—A comparison between two approaches by Osberghaus, A., Hepbildikler, S., Nath, S., Haindl, M., von Lieres, E., Hubbuch, J.

“…► We compare two methods for the determination of parameters for the SMA model. ► We determine SMA parameters for three common proteins at pH 5 and pH 7. ►…”
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Optimizing a chromatographic three component separation: A comparison of mechanistic and empiric modeling approaches by Osberghaus, A., Hepbildikler, S., Nath, S., Haindl, M., von Lieres, E., Hubbuch, J.

“…► Empiric and mechanistic modeling for chromatography optimization are compared. ► We determine and discuss the parameters for both modeling approaches. ► A…”
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CFD analysis of large‐scale bioreactor conditions for guiding free‐flowing sensor development and operation by Ho, P., Stute, B., von Lieres, E.

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Current capabilities and future development of the CADET platform for chromatography modeling by Leweke, S., Heymann, W., von Lieres, E.

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High‐definition simulation of packed‐bed liquid chromatography by Rao, J., Behr, M., von Lieres, E.

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Coarse‐grained simulation for the analysis of microfluidic single‐cell cultivation by Westerwalbesloh, C., Kohlheyer, D., Lieres, E.

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Using quantitative structure‐activity relationship models to predict protein properties for chromatographic separation of host cell proteins by Jäpel, R. C., Müschen, C., Lieres, E., Buyel, J. F.

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Integrated Modeling of Transport Processes, Buffer Equilibria, and Biochemical Reactions in Chromatography Columns Using CADET by Diedrich, J., Leweke, S., von Lieres, E.

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Surface bound adsorption in a microfluidic T-sensor: Numerical comparison and optimization of 2D and 3D models and of sensor designs by Winz, R.M., Wiechert, W., von Lieres, E.

“…We compare models in two and three spatial dimensions for describing the interplay of convection, diffusion and adsorption in the main channel of a…”
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Multi‐state steric mass action model applied to binding of mAb on tentacle resins under high loading conditions by Diedrich, J., Heymann, W., Leweke, S., Lieres, E., Hunt, S., Todd, R., Kunert, C., Johnson, W.

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Education correction for neurocognitive testing by Haussmann, Robert, Sauer, Cathrin, von Lieres und Wilkau, Amrei F. E., Donix, Markus

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Application of Corynebacterium glutamicum beyond Amino Acid Production: Adjustment of Medium Composition Unravels Potential for Secretory Protein Production by Hemmerich, J., Freier, L., Jurischka, S., Schöler, K., von Lieres, E., Oldiges, M.

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Comparison of Different Cultivation Chamber Designs for Microfluidic Bioreactors by Westerwalbesloh, C., Grünberger, A., Wiechert, W., Kohlheyer, D., von Lieres, E.

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High Throughput Screening for the Design and Optimization of Chromatographic Processes: Automated Optimization of Chromatographic Phase Systems by Susanto, A., Treier, K., Knieps-Grünhagen, E., von Lieres, E., Hubbuch, J.

“…Chromatographic processes can be optimized in various ways. However, the two most prominent approaches are either based on statistical data analysis or on…”
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High Throughput Screening for the Design and Optimization of Chromatographic Processes: Assessment of Model Parameter Determination from High Throughput Compatible Data by Susanto, A., Knieps-Grünhagen, E., von Lieres, E., Hubbuch, J.

“…Chromatographic processes can be optimized in various ways, and the two most prominent approaches are based either on statistical data analysis or on…”
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Detection, Quantification, and Propagation of Uncertainty in High-Throughput Experimentation by Monte Carlo Methods by Osberghaus, A., Baumann, P., Hepbildikler, S., Nath, S., Haindl, M., von Lieres, E., Hubbuch, J.

“…Since the efficiency and speed of computing has increased significantly in the last decades, in silico‐approaches, e.g., quasi‐experimental analyses based on…”
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Familial risk of dementia and mediators of memory clinic referrals by Haussmann, Robert, Nilles, Fabienne, Sauer, Cathrin, von Lieres und Wilkau, Amrei F. E., Donix, Katharina L., Donix, Markus

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Mechanistic modeling and optimization of complex buffer pH in packed‐bed chromatography by Schmölder, J., von Lieres, E.

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