Search Results - "von Kessler, Doris P."

Skinny Hedgehog, an Acyltransferase Required for Palmitoylation and Activity of the Hedgehog Signal by Chamoun, Zeina, Mann, Randall K., Nellen, Denise, von Kessler, Doris P., Bellotto, Manolo, Beachy, Philip A., Basler, Konrad

“…One of the most dominant influences in the patterning of multicellular embryos is exerted by the Hedgehog (Hh) family of secreted signaling proteins. Here, we…”
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Nuclear Trafficking of Cubitus interruptus in the Transcriptional Regulation of Hedgehog Target Gene Expression by Chen, Chien-Huan, von Kessler, Doris P, Park, Woojin, Wang, Baolin, Ma, Yong, Beachy, Philip A

“…Transcriptional activation of Hedgehog (Hh) target genes requires Cubitus interruptus, a 155 kDa cytoplasmic zinc finger protein (Ci155), which in the absence…”
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Hedgehog Patterning Activity: Role of a Lipophilic Modification Mediated by the Carboxy-Terminal Autoprocessing Domain by Porter, Jeffery A, Ekker, Stephen C, Park, Woo-Jin, von Kessler, Doris P, Young, Keith E, Chen, Chien-Huan, Ma, Yong, Woods, Amina S, Cotter, Robert J, Koonin, Eugene V, Beachy, Philip A

“…Autocatalytic processing mediated by the carboxy-terminal domain of the hedgehog (hh) protein precursor (Hh) generates an amino-terminal product that accounts…”
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Hedgehog Signal Transduction via Smoothened Association with a Cytoplasmic Complex Scaffolded by the Atypical Kinesin, Costal-2 by Lum, Lawrence, Zhang, Chi, Oh, Sekyung, Mann, Randall K., von Kessler, Doris P., Taipale, Jussi, Weis-Garcia, Frances, Gong, Ruoyu, Wang, Baolin, Beachy, Philip A.

“…The seven-transmembrane protein Smoothened (Smo) transduces extracellular activation of the Hedgehog (Hh) pathway by an unknown mechanism to increase…”
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Patterning activities of vertebrate hedgehog proteins in the developing eye and brain by Ekker, Stephen C., Ungar, Anne R., Greenstein, Penny, von Kessler, Doris P., Porter, Jeffery A., Moon, Randall T., Beachy, Philip A.

“…Background: The hedgehog (hh) family of secreted signaling proteins is responsible for developmental patterning in a variety of systems, including the neural…”
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The product of hedgehog autoproteolytic cleavage active in local and long-range signalling by Porter, Jeffery A, von Kessler, Doris P, Ekker, Stephen C, Young, Keith E, Lee, John J, Moses, Kevin, Beachy, Philip A

“…The secreted protein products of the hedgehog (hh) gene family are associated with local and long-range signalling activities that are responsible for…”
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Autoproteolysis in hedgehog Protein Biogenesis by Lee, John J., Ekker, Stephen C., von Kessler, Doris P., Porter, Jeffrey A., Sun, Benjamin I., Beachy, Philip A.

“…Extracellular signaling proteins encoded by the hedgehog (hh) multigene family are responsible for the patterning of a variety of embryonic structures in…”
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Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog by Lee, J J, von Kessler, D P, Parks, S, Beachy, P A

“…The segment polarity genes engrailed and wingless are expressed in neighboring stripes of cells on opposite sides of the Drosophila parasegment boundary. Each…”
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Products, genetic linkage and limb patterning activity of a murine hedgehog gene by Chang, David T., López, Alric, Kessler, Doris P. von, Chiang, Chin, Simandl, B. Kay, Zhao, Renbin, Seldin, Michael F., Fallon, John F., Beachy, Philip A.

“…The hedgehog (hh) segmentation gene of Drosophila melanogaster encodes a secreted signaling protein that functions in the patterning of larval and adult…”
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Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis by Ekker, S C, McGrew, L L, Lai, C J, Lee, J J, von Kessler, D P, Moon, R T, Beachy, P A

“…The hedgehog family of signaling proteins is associated with a variety of spatial patterning activities in insects and vertebrates. Here we show that new…”
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Differential DNA sequence recognition is a determinant of specificity in homeotic gene action by Ekker, S.C., Kessler, D.P., Beachy, P.A.

“…The homeotic genes of Drosophila encode transcriptional regulatory proteins that specify distinct segment identities. Previous studies have implicated the…”
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Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila by Ekker, S.C, Young, K.E, Von Kessler, D.P, Beachy, P.A

“…The 61 amino acid homeodomain is conserved among members of a family of eukaryotic DNA-binding proteins that play regulatory roles in transcription and in…”
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Cooperative binding of an Ultrabithorax homeodomain protein to nearby and distant DNA sites by BEACHY, P. A, VARKEY, J, YOUNG, K. E, VON KESSLER, D. P, SUN, B. I, EKKER, S. C

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cooperative Binding of an Ultrabithorax Homeodomain Protein to Nearby and Distant DNA Sites by Beachy, Philip A., Varkey, Jacob, Young, Keith E., Von Kessler, Doris P., Sun, Benjamin I., Ekker, Stephen C.

“…Cooperativity in binding of regulatory proteins to multiple DNA sites can heighten the sensitivity and specificity of the transcriptional response. We report…”
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