Search Results - "von Itzstein, M"

Galectin-3 in pre-B acute lymphoblastic leukemia by Fei, F, Abdel-Azim, H, Lim, M, Arutyunyan, A, von Itzstein, M, Groffen, J, Heisterkamp, N

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Neuraminidase Inhibitor Sensitivity and Receptor-Binding Specificity of Cambodian Clade 1 Highly Pathogenic H5N1 Influenza Virus by NAUGHTIN, M, DYASON, J. C, MARDY, S, SORN, S, VON ITZSTEIN, M, BUCHY, P

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Targeting human respiratory syncytial virus transcription anti-termination factor M2-1 to inhibit in vivo viral replication by Bailly, B., Richard, C.-A., Sharma, G., Wang, L., Johansen, L., Cao, J., Pendharkar, V., Sharma, D.-C., Galloux, M., Wang, Y., Cui, R., Zou, G., Guillon, P., von Itzstein, M., Eléouët, J.-F., Altmeyer, R.

“…Human respiratory syncytial virus (hRSV) is a leading cause of acute lower respiratory tract infection in infants, elderly and immunocompromised individuals…”
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Recent Advances in the Synthesis of Sialic Acid Derivatives and Sialylmimetics as Biological Probes by Kiefel, Milton J, von Itzstein, Mark

“…Kiefel and Itzstein focus on the salient features of the recent advances in sialic acid chemistry, primarily focusing on the last three years. The synthesis…”
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Production of an enterotoxin by a gastro-enteritis-associated Aeromonas strain by TROWER, C.J, ABO, S, MAJEED, K.N, ITZSTEIN, M. VON

“…Departments of Medicinal Chemistry and *Pharmaceutics, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia Corresponding author: Professor…”
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Effect of substrate aglycon on enzyme mechanism in the reaction of sialidase from influenza virus by Tiralongo, J., Pegg, M.S., von Itzstein, M.

“…The effect of substrate aglycon on enzyme mechanism of sialidase from influenza virus was investigated by kinetic isotope effects using the substrates 4-…”
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Recent strategies in the search for new anti-influenza therapies by Wilson, J C, von Itzstein, M

“…Influenza is a highly contagious, acute upper respiratory tract disease caused by influenza virus, a member of the Orthomyxoviridae family. The viral particles…”
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Novel bismuth compounds have in vitro activity against Helicobacter pylori by Midolo, P.D., Norton, A., von Itzstein, M., Lambert, J.R.

“…Abstract The increasing antimicrobial resistance in Helicobacter pylori has led to the search for new therapeutic agents. In this in vitro study, novel…”
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Synthesis and Biological Evaluation of Sialylmimetics as Rotavirus Inhibitors by Fazli, Ashmath, Bradley, Susan J, Kiefel, Milton J, Jolly, Clare, Holmes, Ian H, von Itzstein, Mark

“…Rotaviruses cause severe gastroenteritis in infants and are estimated to be responsible for over 600 000 deaths annually, primarily in developing countries…”
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Design and Synthesis of a Biologically Active Antibody Mimic Based on an Antibody-Antigen Crystal Structure by Smythe, M. L, von Itzstein, M

“…We have used the crystal structure of an N9 sialidase (antigen)-NC41 (antibody) complex to design a low molecular weight compound that mimics the binding…”
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Novel bismuth compounds have in vitro activity against Helicobacter pylori by Midolo, P.D, Norton, A, von Itzstein, M, Lambert, J.R

“…The increasing antimicrobial resistance in Helicobacter pylori has led to the search for new therapeutic agents. In this in vitro study, novel compounds…”
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Synthesis and influenza virus sialidase inhibitory activity of analogues of 4-guanidino-Neu5Ac2en (GG167) with modified 5-substituents by Smith, PW, Starkey, ID, Howes, PD, Sollis, SL, Keeling, SP, Cherry, PC, von Itzstein, M, Wu, WY, Jin, B

“…Analogues of 4-guanidino-Neu5Ac2en (GG167) have been prepared containing alternative amide and sulfonamide substituents at the 5-position. (4 S,5 R,6…”
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Lysosomal Sialidase (Neuraminidase-1) Is Targeted to the Cell Surface in a Multiprotein Complex That Facilitates Elastic Fiber Assembly by Hinek, Aleksander, Pshezhetsky, Alexey V., von Itzstein, Mark, Starcher, Barry

“…We have established previously that the 67-kDa elastin-binding protein (EBP), identical to the spliced variant of β-galactosidase, acts as a recyclable…”
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Insight into Host Cell Carbohydrate-recognition by Human and Porcine Rotavirus from Crystal Structures of the Virion Spike Associated Carbohydrate-binding Domain (VP8) by Blanchard, Helen, Yu, Xing, Coulson, Barbara S., von Itzstein, Mark

“…Rotavirus infection leads to the death of half a million children annually. The exact specifics of interaction between rotavirus particles and host cells…”
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Avian influenza virus, a very sticky situation by von Itzstein, Mark

“…The appearance of the highly pathogenic avian influenza virus H5N1 highlighted the potential impact of influenza virus on humanity. The emergence of this high…”
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Second Sialic Acid Binding Site in Newcastle Disease Virus Hemagglutinin-Neuraminidase: Implications for Fusion by ZAITSEV, Viatcheslav, VON ITZSTEIN, Mark, GROVES, Darrin, KIEFEL, Milton, TAKIMOTO, Toru, PORTNER, Allen, TAYLOR, Garry

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Targeting human respiratory syncytial virus transcription anti-termination factor M2-1 to inhibit in vivo viral replication by Bailly, B., Richard, C.-A., Sharma, G., Wang, L., Johansen, L., Cao, J., Pendharkar, V., Sharma, D.-C., Galloux, Marie, Wang, Y., Cui, R., Zou, G., Guillon, P., von Itzstein, M., Eléouët, J.-F., Altmeyer, R.

“…Abstract Human respiratory syncytial virus (hRSV) is a leading cause of acute lower respiratory tract infection in infants, elderly and immunocompromised…”
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Sialic Acid Recognition by Vibrio cholerae Neuraminidase by Moustafa, Ibrahim, Connaris, Helen, Taylor, Margaret, Zaitsev, Viateslav, Wilson, Jennifer C., Kiefel, Milton J., von Itzstein, Mark, Taylor, Garry

“…Vibrio cholerae neuraminidase (VCNA) plays a significant role in the pathogenesis of cholera by removing sialic acid from higher order gangliosides to unmask…”
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Hot, sweet and sticky: the glycobiology of Plasmodium falciparum by von Itzstein, Mark, Plebanski, Magdalena, Cooke, Brian M, Coppel, Ross L

“…Carbohydrate structures that decorate the surface of cells are increasingly recognized as playing important roles in the biology of host–pathogen interactions…”
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Rapid, clean, and mild O-acetylation of alcohols and carbohydrates in an ionic liquid by Forsyth, Stewart A, MacFarlane, Douglas R, Thomson, Robin J, von Itzstein, Mark

“…Archetypal O-acetylation reactions of alcohols and carbohydrates proceed rapidly in high yield under mild conditions in a dicyanamide based ionic liquid, that…”
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