Search Results - "von Heijne, G"
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Feature-based prediction of non-classical and leaderless protein secretion
Published in Protein engineering, design and selection (01-04-2004)“…We present a sequence-based method, SecretomeP, for the prediction of mammalian secretory proteins targeted to the non-classical secretory pathway, i.e…”
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Comparative analysis of amino acid distributions in integral membrane proteins from 107 genomes
Published in Proteins, structure, function, and bioinformatics (01-09-2005)“…We have performed a comparative analysis of amino acid distributions in predicted integral membrane proteins from a total of 107 genomes. A procedure for…”
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dominant white, Dun and Smoky color variants in chicken are associated with insertion/deletion polymorphisms in the PMEL17 gene
Published in Genetics (Austin) (01-11-2004)“…Dominant white, Dun, and Smoky are alleles at the Dominant white locus, which is one of the major loci affecting plumage color in the domestic chicken. Both…”
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The membrane protein universe: what's out there and why bother?
Published in Journal of internal medicine (01-06-2007)“… Chances are that you have come across membrane proteins many times in your professional life: ion channels, aquaporins, G‐protein‐coupled receptors, drug…”
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Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method
Published in Protein engineering (01-06-1997)“…A new, simple method for predicting transmembrane segments in integral membrane proteins has been developed. It is based on low-stringency dot-plots of the…”
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Determination of the distance between the oligosaccharyltransferase active site and the endoplasmic reticulum membrane
Published in The Journal of biological chemistry (15-03-1993)“…By in vitro transcription/translation of model proteins in the presence of dog pancreas microsomes, we have measured the minimum distance of an acceptor site…”
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Recognition of transmembrane helices by the endoplasmic reticulum translocon
Published in Nature (27-01-2005)“…Membrane proteins depend on complex translocation machineries for insertion into target membranes. Although it has long been known that an abundance of…”
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ChloroP, a neural network-based method for predicting chloroplast transit peptides and their cleavage sites
Published in Protein science (01-05-1999)“…We present a neural network based method (ChloroP) for identifying chloroplast transit peptides and their cleavage sites. Using cross-validation, 88% of the…”
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Effect of acute hyperketonemia on the cerebral uptake of ketone bodies in nondiabetic subjects and IDDM patients
Published in American journal of physiology: endocrinology and metabolism (01-07-2002)“…Using R-beta-[1-(11)C]hydroxybutyrate and positron emission tomography, we studied the effect of acute hyperketonemia (range 0.7-1.7 micromol/ml) on cerebral…”
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Genome‐wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms
Published in Protein science (01-04-1998)“…We have carried out detailed statistical analyses of integral membrane proteins of the helix‐bundle class from eubacterial, archaean, and eukaryotic organisms…”
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Disulfide Bond Formation and Cysteine Exclusion in Gram-positive Bacteria
Published in The Journal of biological chemistry (29-01-2010)“…Most secretion pathways in bacteria and eukaryotic cells are challenged by the requirement for their substrate proteins to mature after they traverse a…”
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Amino acid distributions around O-linked glycosylation sites
Published in Biochemical journal (15-04-1991)“…To study the sequence requirements for addition of O-linked N-acetylgalactosamine to proteins, amino acid distributions around 174 O-glycosylation sites were…”
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Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125
Published in Genome research (01-10-2005)“…A considerable fraction of life develops in the sea at temperatures lower than 15 degrees C. Little is known about the adaptive features selected under those…”
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Protein targeting signals
Published in Current opinion in cell biology (01-08-1990)Get more information
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Properties of N-terminal tails in G-protein coupled receptors: a statistical study
Published in Protein engineering (01-07-1995)“…The extramembraneous segments in a large collection of G-protein coupled receptors (GPCRs) have been analysed in terms of amino acid composition and length. It…”
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A Nine-transmembrane Domain Topology for Presenilin 1
Published in The Journal of biological chemistry (21-10-2005)“…Presenilin (PS) provides the catalytic core of the γ-secretase complex. γ-Secretase activity leads to generation of the amyloid β-peptide, a key event…”
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Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
Published in Protein engineering (01-01-1997)“…We have developed a new method for the identification of signal peptides and their cleavage sites based on neural networks trained on separate sets of…”
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Membrane topology of the human seipin protein
Published in FEBS letters (17-04-2006)“…The Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2) gene encodes an integral membrane protein, called seipin, of unknown function localized to the…”
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Topology of the Membrane-Associated Hepatitis C Virus Protein NS4B
Published in Journal of Virology (01-05-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Topology, subcellular localization, and sequence diversity of the Mlo family in plants
Published in The Journal of biological chemistry (03-12-1999)“…Barley Mlo defines the founder of a novel class of plant integral membrane proteins. Lack of the wild type protein leads to broad spectrum disease resistance…”
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