Search Results - "von Harsdorf, Ruediger"

p27 Protein Protects Metabolically Stressed Cardiomyocytes from Apoptosis by Promoting Autophagy by Sun, Xuetao, Momen, Abdul, Wu, Jun, Noyan, Hossein, Li, Renke, von Harsdorf, Rüdiger, Husain, Mansoor

“…p27Kip1 (p27), a key regulator of cell division, has been implicated in autophagy of cancer cells. However, its role in autophagy, the evolutionarily conserved…”
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Anti-apoptotic function of the E2F transcription factor 4 (E2F4)/p130, a member of retinoblastoma gene family in cardiac myocytes by Dingar, Dharmendra, Konecny, Filip, Zou, Jian, Sun, Xuetao, von Harsdorf, Rüdiger

“…Abstract The E2F4–p130 transcriptional repressor complex is a cell-cycle inhibitor in mitotic cells. However, the role of E2F4/p130 in differentiated cells is…”
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Protein kinase CK2 links extracellular growth factor signaling with the control of p27(Kip1) stability in the heart by Hauck, Ludger, Harms, Christoph, An, Junfeng, Rohne, Jens, Gertz, Karen, Dietz, Rainer, Endres, Matthias, von Harsdorf, Rüdiger

“…p27(Kip1) (p27) blocks cell proliferation through the inhibition of cyclin-dependent kinase-2 (Cdk2). Despite its robust expression in the heart, little is…”
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Post-myocardial infarct p27 fusion protein intravenous delivery averts adverse remodelling and improves heart function and survival in rodents by KONECNY, Filip, JIAN ZOU, HUSAIN, Mansoor, HARSDORF, Rüdiger Von

“…P27Kip1 (p27) blocks cell proliferation through the inhibition of cyclin-dependent kinase 2 (cdk-2). Despite robust expression in the heart, little is known…”
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Mitochondrial fission leads to Smac/DIABLO release quenched by ARC by Li, Jincheng, Li, Yanrui, Qin, Danian, von Harsdorf, Ruediger, Li, Peifeng

“…Apoptosis plays a critical role for the development of a variety of cardiac diseases. Cardiomyocytes are enriched in mitochondria, while mitochondrial fission…”
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Phosphatidylinositol 3-Akt-kinase-dependent phosphorylation of p21(Waf1/Cip1) as a novel mechanism of neuroprotection by glucocorticoids by Harms, Christoph, Albrecht, Katharina, Harms, Ulrike, Seidel, Kerstin, Hauck, Ludger, Baldinger, Tina, Hübner, Denise, Kronenberg, Golo, An, Junfeng, Ruscher, Karsten, Meisel, Andreas, Dirnagl, Ulrich, von Harsdorf, Rüdiger, Endres, Matthias, Hörtnagl, Heide

“…The role of glucocorticoids in the regulation of apoptosis remains incongruous. Here, we demonstrate that corticosterone protects neurons from apoptosis by a…”
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The Adverse Long-Term Impact of Renal Impairment in Patients Undergoing Percutaneous Coronary Intervention in the Drug-Eluting Stent Era by Appleby, Clare E, Ivanov, Joan, Lavi, Shahar, Mackie, Karen, Horlick, Eric M, Ing, Douglas, Overgaard, Christopher B, Seidelin, Peter H, von Harsdorf, Rüdiger, Džavík, Vladimír

“…BACKGROUND—An observational study determining the long-term impact of chronic kidney disease (CKD) on patients undergoing percutaneous coronary intervention at…”
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Protein kinase CK2 links extracellular growth factor signaling with the control of p27 super(Kip1) stability in the heart by Hauck, Ludger, Harms, Christoph, Rohne, Jens, Gertz, Karen, Dietz, Rainer, Endres, Matthias, Von Harsdorf, Ruediger

“…p27 super(Kip1) (p27) blocks cell proliferation through the inhibition of cyclin-dependent kinase-2 (Cdk2). Despite its robust expression in the heart, little…”
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The Xanthine Oxidase Inhibitors Oxypurinol and Allopurinol Reduce Wasting and Improve Cardiac Function in Experimental Cancer Cachexia by Springer, Jochen, Hartmann, Anika, Palus, Sandra, Adams, Volker, von Harsdorf, Ruediger, Anker, Stefan D, Doehner, Wolfram

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Critical Role for FoxO3a-Dependent Regulation of p21 super(CIP1/WAF1) in Response to Statin Signaling in Cardiac Myocytes by Hauck, Ludger, Harms, Christoph, Grothe, Daniela, An, Junfeng, Gertz, Karen, Kronenberg, Golo, Dietz, Rainer, Endres, Matthias, von Harsdorf, Ruediger

“…Statins are widely used clinical drugs that exert beneficial growth-suppressive effects in patients with cardiac hypertrophy. We investigated the role of the…”
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Phosphatidylinositol 3-Akt-Kinase-Dependent Phosphorylation of p21 super(Waf1/Cip1) as a Novel Mechanism of Neuroprotection by Glucocorticoids by Harms, Christoph, Albrecht, Katharina, Harms, Ulrike, Seidel, Kerstin, Hauck, Ludger, Baldinger, Tina, Huebner, Denise, Kronenberg, Golo, An, Junfeng, Ruscher, Karsten, Meisel, Andreas, Dirnagl, Ulrich, von Harsdorf, Ruediger, Endres, Matthias, Hoertnagl, Heide

“…The role of glucocorticoids in the regulation of apoptosis remains incongruous. Here, we demonstrate that corticosterone protects neurons from apoptosis by a…”
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