Search Results - "von Hagen, Jörg"
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Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study
Published in Molecules (Basel, Switzerland) (16-03-2021)“…The influence of a topically applied formulation containing components of natural moisturizing factor (NMF) on barrier-related parameters of the stratum…”
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Drug Development for Target Ribosomal Protein rpL35/uL29 for Repair of LAMB3R635X in Rare Skin Disease Epidermolysis Bullosa
Published in Skin pharmacology and physiology (01-06-2021)“…Epidermolysis bullosa (EB) describes a family of rare genetic blistering skin disorders. Various subtypes are clinically and genetically heterogeneous, and a…”
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Circadian Oscillations in Skin and Their Interconnection with the Cycle of Life
Published in International journal of molecular sciences (15-03-2023)“…Periodically oscillating biological processes, such as circadian rhythms, are carefully concerted events that are only beginning to be understood in the…”
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Amino acids in the cultivation of mammalian cells
Published in Amino acids (01-05-2016)“…Amino acids are crucial for the cultivation of mammalian cells. This importance of amino acids was realized soon after the development of the first cell lines,…”
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Subcellular protein extraction from human pancreatic cancer tissues
Published in BioTechniques (01-04-2009)“…Proteins are the major class of effector molecules in cellular systems. For the identification of functional differences between normal and diseased tissues, a…”
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Carotenoids in Human Skin In Vivo: Antioxidant and Photo-Protectant Role against External and Internal Stressors
Published in Antioxidants (01-07-2022)“…The antioxidant system of the human body plays a crucial role in maintaining redox homeostasis and has an important protective function. Carotenoids have…”
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Solvent-Containing Closure Material Can Be Used to Prevent Follicular Penetration of Caffeine and Fluorescein Sodium Salt on Porcine Ear Skin
Published in Skin pharmacology and physiology (01-06-2020)“…The skin represents a drug delivery portal. The establishment of a skin model capable of distinguishing between the follicular and intercellular penetration…”
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Topical Peroxisome Proliferator-Activated Receptor Agonist Induces Molecular Alterations Enhancing Barrier Function and Water-Holding Capacity of the Human Stratum Corneum In Vivo
Published in Cosmetics (Basel) (01-04-2024)“…The peroxisome proliferator-activated receptor (PPAR) ligands modulate a variety of skin functions but are rarely used in cosmetics. The aim of this…”
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Microdialysis on Ex Vivo Porcine Ear Skin Can Validly Study Dermal Penetration including the Fraction of Transfollicular Penetration—Demonstrated on Caffeine Nanocrystals
Published in Nanomaterials (Basel, Switzerland) (14-09-2021)“…Common ex vivo methods for penetration investigations often fail to monitor transfollicular penetration appropriately. In the present investigation, the…”
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Ionische Flüssigkeiten in biotechnologischen Anwendungen
Published in Biospektrum (01-11-2011)“…Zusammenfassung Ionische Flüssigkeiten stellen bei Raumtemperatur eine faszinierende, unkonventionelle Alternative zu Wasser oder Lösemittel-basierenden…”
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Investigation of transfollicular caffeine penetration using microdialysis on ex vivo porcine ear skin
Published in European journal of pharmaceutics and biopharmaceutics (01-12-2020)“…[Display omitted] The aim of this study was to develop an ex vivo method that allows to quantify the transfollicular penetration of topically applied…”
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Manufacturing ultra-concentrated liquid feeds: Transitioning the aqueous solubility barrier of the feed amino acids cysteine and tyrosine
Published in BMC proceedings (14-12-2015)“…Fed-batch cultivation is currently the most prominent process for the production of Biologics using mammalian cell lines such as CHO cells. Performance of…”
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Carotenoids in Human SkinIn Vivo: Antioxidant and Photo-Protectant Role against External and Internal Stressors
Published in Antioxidants (26-07-2022)Get full text
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Compaction of chemically defined cell culture media increases its dissolution rate through an increase of solvent accessible surface area
Published in Powder technology (01-11-2016)“…Cultivation of mammalian cells for the generation of therapeutics requires the use of cell culture media which is a defined mixture of nutrients including…”
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Isolation of subcellular organelles and structures
Published in Methods in enzymology (2009)“…One of the major challenges in functional proteomics is the separation of complex protein mixtures to allow detection of low abundance proteins and provide for…”
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