Search Results - "von Einem, Jens"

Human Cytomegalovirus pUL47 Modulates Tegumentation and Capsid Accumulation at the Viral Assembly Complex by Cappadona, Ilaria, Villinger, Clarissa, Schutzius, Gabi, Mertens, Thomas, von Einem, Jens

“…Human cytomegalovirus (HCMV) tegument protein pUL47 is an interaction partner of pUL48 and highly conserved among herpesviruses. It is closely associated with…”
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The Tegument Protein UL71 of Human Cytomegalovirus Is Involved in Late Envelopment and Affects Multivesicular Bodies by SCHAUFLINGER, Martin, FISCHER, Daniela, SCHREIBER, Andreas, CHEVILLOTTE, Meike, WALTHER, Paul, MERTENS, Thomas, VON EINEM, Jens

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The Human Cytomegalovirus Nonstructural Glycoprotein UL148 Reorganizes the Endoplasmic Reticulum by Zhang, Hongbo, Read, Clarissa, Nguyen, Christopher C, Siddiquey, Mohammed N A, Shang, Chaowei, Hall, Cameron M, von Einem, Jens, Kamil, Jeremy P

“…Human cytomegalovirus (HCMV) encodes an endoplasmic reticulum (ER)-resident glycoprotein, UL148, which activates the unfolded protein response (UPR) but is…”
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Nuclear Targeting of Human Cytomegalovirus Large Tegument Protein pUL48 Is Essential for Viral Growth by Brock, Ivonne, Krüger, Marc, Mertens, Thomas, von Einem, Jens

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Major Tegument Protein pp65 of Human Cytomegalovirus Is Required for the Incorporation of pUL69 and pUL97 into the Virus Particle and for Viral Growth in Macrophages by CHEVILLOTTE, Meike, LANDWEHR, Sandra, LINTA, Leonhard, FRASCAROLI, Giada, LÜSKE, Anke, BUSER, Christopher, MERTENS, Thomas, VON EINEM, Jens

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The ULb′ Region of the Human Cytomegalovirus Genome Confers an Increased Requirement for the Viral Protein Kinase UL97 by Wang, Depeng, Li, Gang, Schauflinger, Martin, Nguyen, Christopher C, Hall, Ellie D, Yurochko, Andrew D, von Einem, Jens, Kamil, Jeremy P

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Differentiation between Polymorphisms and Resistance-Associated Mutations in Human Cytomegalovirus DNA Polymerase by CHEVILLOTTE, Meike, ERSING, Ina, MERTENS, Thomas, VON EINEM, Jens

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Fluorescence-Based Assay for Phenotypic Characterization of Human Cytomegalovirus Polymerase Mutations Regarding Drug Susceptibility and Viral Replicative Fitness by CHEVILLOTTE, Meike, SCHUBERT, Axel, MERTENS, Thomas, VON EINEM, Jens

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Quantitative Electron Microscopy to Study HCMV Morphogenesis by Read, Clarissa, Walther, Paul, von Einem, Jens

“…The generation and release of mature virions from human cytomegalovirus (HCMV) infected cells is a multistep process, involving a profound reorganization of…”
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Editorial: Herpesvirus Maturation by Tandon, Ritesh, von Einem, Jens

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Regulatory Interaction between the Cellular Restriction Factor IFI16 and Viral pp65 (pUL83) Modulates Viral Gene Expression and IFI16 Protein Stability by Biolatti, Matteo, Dell'Oste, Valentina, Pautasso, Sara, von Einem, Jens, Marschall, Manfred, Plachter, Bodo, Gariglio, Marisa, De Andrea, Marco, Landolfo, Santo

“…A key player in the intrinsic resistance against human cytomegalovirus (HCMV) is the interferon-γ-inducible protein 16 (IFI16), which behaves as a viral DNA…”
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A Tyrosine-Based Trafficking Motif of the Tegument Protein pUL71 Is Crucial for Human Cytomegalovirus Secondary Envelopment by Dietz, Andrea N, Villinger, Clarissa, Becker, Stefan, Frick, Manfred, von Einem, Jens

“…The human cytomegalovirus (HCMV) tegument protein pUL71 is required for efficient secondary envelopment and accumulates at the Golgi compartment-derived viral…”
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Human Monocytes Are Suitable Carriers for the Delivery of Oncolytic Herpes Simplex Virus Type 1 In Vitro and in a Chicken Embryo Chorioallantoic Membrane Model of Cancer by Reale, Alberto, Krutzke, Lea, Cadamuro, Massimiliano, Vitiello, Adriana, von Einem, Jens, Kochanek, Stefan, Palù, Giorgio, Parolin, Cristina, Calistri, Arianna

“…Oncolytic viruses (OVs) are promising therapeutics for tumors with a poor prognosis. An OV based on herpes simplex virus type 1 (oHSV-1), talimogene…”
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Two-step red-mediated recombination for versatile high-efficiency markerless DNA manipulation in Escherichia coli by Tischer, B Karsten, von Einem, Jens, Kaufer, Benedikt, Osterrieder, Nikolaus

“…Red recombination using PCR-amplified selectable markers is a well-established technique for mutagenesis of large DNA molecules in Escherichia coli. The system…”
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Impact of ETIF Deletion on Safety and Immunogenicity of Equine Herpesvirus Type 1-Vectored Vaccines by Helga Hofmann-Sieber, Jens Wild, Nicole Fiedler, Karsten Tischer, Jens von Einem, Nikolaus Osterrieder, Heike Hofmann, Josef Köstler, Ralf Wagner

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Human cytomegalovirus deploys molecular mimicry to recruit VPS4A to sites of virus assembly by Butt, Benjamin G, Fischer, Daniela, Rep, Alison R, Schauflinger, Martin, Read, Clarissa, Böck, Thomas, Hirner, Manuel, Wienen, Frederik, Graham, Stephen C, von Einem, Jens

“…The AAA-type ATPase VPS4 is recruited by proteins of the endosomal sorting complex required for transport III (ESCRT-III) to catalyse membrane constriction and…”
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Human Cytomegalovirus Uses a Host Stress Response To Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very-Long-Chain Fatty Acids by Xi, Yuecheng, Lindenmayer, Lena, Kline, Ian, von Einem, Jens, Purdy, John G

“…Stress and virus infection regulate lipid metabolism. Human cytomegalovirus (HCMV) infection induces fatty acid (FA) elongation and increases the abundance of…”
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Improved automatic detection of herpesvirus secondary envelopment stages in electron microscopy by augmenting training data with synthetic labelled images generated by a generative adversarial network by Shaga Devan, Kavitha, Walther, Paul, von Einem, Jens, Ropinski, Timo, Kestler, Hans, Read, Clarissa

“…Detailed analysis of secondary envelopment of the herpesvirus human cytomegalovirus (HCMV) by transmission electron microscopy (TEM) is crucial for…”
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Secondary Envelopment of Human Cytomegalovirus Is a Fast Process Utilizing the Endocytic Compartment as a Major Membrane Source by Bergner, Tim, Cortez Rayas, Laura, Freimann, Gesa, Read, Clarissa, von Einem, Jens

“…Secondary envelopment of the human cytomegalovirus (HCMV) is a critical but not well-understood process that takes place at the cytoplasmic viral assembly…”
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Dynamic monitoring of viral gene expression reveals rapid antiviral effects of CD8 T cells recognizing the HCMV-pp65 antigen by Khan, Fawad, Müller, Thomas R, Kasmapour, Bahram, Ynga-Durand, Mario Alberto, Eiz-Vesper, Britta, von Einem, Jens, Busch, Dirk H, Cicin-Sain, Luka

“…Human Cytomegalovirus (HCMV) is a betaherpesvirus that causes severe disease in immunocompromised transplant recipients. Immunotherapy with CD8 T cells…”
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