Search Results - "von Deimling, Andreas"
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EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood
Published in Nature reviews. Clinical oncology (01-03-2021)“…In response to major changes in diagnostic algorithms and the publication of mature results from various large clinical trials, the European Association of…”
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2
EANO guidelines for the diagnosis and treatment of meningiomas
Published in The lancet oncology (01-09-2016)“…Summary Although meningiomas are the most common intracranial tumours, the level of evidence to provide recommendations for the diagnosis and treatment of…”
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3
Tumor cell plasticity, heterogeneity, and resistance in crucial microenvironmental niches in glioma
Published in Nature communications (12-02-2021)“…Both the perivascular niche (PVN) and the integration into multicellular networks by tumor microtubes (TMs) have been associated with progression and…”
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4
Fibroblast Activation Protein-Specific PET/CT Imaging in Fibrotic Interstitial Lung Diseases and Lung Cancer: A Translational Exploratory Study
Published in Journal of Nuclear Medicine (01-01-2022)“…Interstitial lung diseases (ILDs) comprise over 200 parenchymal lung disorders. Among them, fibrosing ILDs, especially idiopathic pulmonary fibrosis, are…”
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Machine learning workflows to estimate class probabilities for precision cancer diagnostics on DNA methylation microarray data
Published in Nature protocols (01-02-2020)“…DNA methylation data-based precision cancer diagnostics is emerging as the state of the art for molecular tumor classification. Standards for choosing…”
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Epidermal Growth Factor Receptor Variant III (EGFRvIII) Positivity in EGFR -Amplified Glioblastomas: Prognostic Role and Comparison between Primary and Recurrent Tumors
Published in Clinical cancer research (15-11-2017)“…Approximately 40% of all glioblastomas have amplified the gene, and about half of these tumors express the EGFRvIII variant. The prognostic role of EGFRvIII in…”
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IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO
Published in Acta neuropathologica (01-06-2015)“…The WHO 2007 classification of tumors of the CNS distinguishes between diffuse astrocytoma WHO grade II (A II WHO2007 ) and anaplastic astrocytoma WHO grade…”
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CIC protein instability contributes to tumorigenesis in glioblastoma
Published in Nature communications (08-02-2019)“…Capicua (CIC) is a transcriptional repressor that counteracts activation of genes downstream of receptor tyrosine kinase (RTK)/Ras/ERK signaling. It is…”
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9
Delineation of Two Clinically and Molecularly Distinct Subgroups of Posterior Fossa Ependymoma
Published in Cancer cell (16-08-2011)“…Despite the histological similarity of ependymomas from throughout the neuroaxis, the disease likely comprises multiple independent entities, each with a…”
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Long-Term Outcome After Radiotherapy in Patients With Atypical and Malignant Meningiomas—Clinical Results in 85 Patients Treated in a Single Institution Leading to Optimized Guidelines for Early Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-07-2012)“…Purpose Previously, we could show that the new World Health Organization (WHO) classification of meningiomas significantly correlated with outcome in patients…”
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11
Primary CNS Alveolar Rhabdomyosarcoma: Importance of Epigenetic and Transcriptomic Assays for Accurate Diagnosis
Published in Journal of neuropathology and experimental neurology (01-11-2019)“…Abstract We present the case of a 22-year-old woman who developed increasing headaches, nausea, and vomiting. Imaging identified a 3 × 3 cm heterogeneously…”
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Intimal sarcomas and undifferentiated cardiac sarcomas carry mutually exclusive MDM2, MDM4, and CDK6 amplifications and share a common DNA methylation signature
Published in Modern pathology (01-12-2021)“…Undifferentiated mesenchymal tumors arising from the inner lining (intima) of large arteries are classified as intimal sarcomas (ISA) with MDM2 amplification…”
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Increased Radiation-Associated T-Cell Infiltration in Recurrent IDH-Mutant Glioma
Published in International journal of molecular sciences (21-10-2020)“…Most gliomas are associated with a fatal prognosis and remain incurable because of their infiltrative growth. Consequently, the addition of immunotherapy to…”
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14
2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size
Published in International journal of cancer (01-08-2012)“…IDH1/2 mutations occur at high frequency in diffusely infiltrating gliomas of the WHO grades II and III and were identified as a strong prognostic marker in…”
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15
Frame-based stereotactic biopsies using an intraoperative MR-scanner are as safe and effective as conventional stereotactic procedures
Published in PloS one (23-10-2018)“…Frame-based stereotactic biopsy (FBSB) is a minimally-invasive and effective procedure for the diagnosis of brain lesions and will likely gain clinical…”
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16
The age of adult pilocytic astrocytoma cells
Published in Oncogene (22-04-2021)“…Adult pilocytic astrocytomas (PAs) have been regarded as indistinguishable from pediatric PAs in terms of genome-wide expression and methylation patterns. It…”
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Extent of Resection, MGMT Promoter Methylation Status and Tumor Location Independently Predict Progression-Free Survival in Adult Sporadic Pilocytic Astrocytoma
Published in Cancers (29-07-2019)“…In adults, pilocytic astrocytomas (PA) account for less than 2% of gliomas, resulting in uncertainty regarding the clinical course and optimal treatment,…”
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18
Sclerosing epithelioid mesenchymal neoplasm of the pancreas – a proposed new entity
Published in Modern pathology (01-03-2020)“…We have encountered pancreatic tumors with unique histologic features, which do not conform to any of the known tumors of the pancreas or other anatomical…”
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Improved Correlation of the Neuropathologic Classification According to Adapted World Health Organization Classification and Outcome After Radiotherapy in Patients With Atypical and Anaplastic Meningiomas
Published in International journal of radiation oncology, biology, physics (01-12-2011)“…Purpose To evaluate the correlation between the 1993 and 2000/2007 World Health Organization (WHO) classification with the outcome in patients with high-grade…”
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Detection of BRAF V600E mutations in skin metastases of malignant melanoma by monoclonal antibody VE1
Published in Journal of the American Academy of Dermatology (01-09-2012)Get full text
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