Search Results - "von Beck, Troy"
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Analysis of rare genetic variants in All of Us cohort patients with common variable immunodeficiency
Published in Frontiers in genetics (02-10-2024)“…Common variable immunodeficiency (CVID) is a group of genetic disorders involving more than a dozen genetic loci and characterized by a deficiency in specific…”
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Atovaquone and Pibrentasvir Inhibit the SARS-CoV-2 Endoribonuclease and Restrict Infection In Vitro but Not In Vivo
Published in Viruses (30-08-2023)“…The emergence of SARS-CoV-1 in 2003 followed by MERS-CoV and now SARS-CoV-2 has proven the latent threat these viruses pose to humanity. While the SARS-CoV-2…”
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A wild boar cathelicidin peptide derivative inhibits severe acute respiratory syndrome coronavirus-2 and its drifted variants
Published in Scientific reports (05-09-2023)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a clear threat to humanity. It has infected over 200 million and killed 4 million people…”
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Lymphoid clonal hematopoiesis: implications for malignancy, immunity, and treatment
Published in Blood cancer journal (New York) (04-01-2023)“…Clonal hematopoiesis (CH) is the age-related expansion of hematopoietic stem cell clones caused by the acquisition of somatic point mutations or mosaic…”
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Early AID expression in developing B cells marks a population with a restricted IgH repertoire favoring D-proximal VH gene usage
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Activation-induced cytidine deaminase (AID) is well characterized in germinal center reactions as a driver of secondary antibody diversification…”
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Repurposed antibiotic and antiviral drugs inhibit the immune evasive endoribonuclease of SARS-CoV-2 and restrict coronavirus infection in vitro
Published in The Journal of immunology (1950) (01-05-2022)“…Abstract Despite the success of SARS-CoV-2 vaccines in curbing viral transmission and severe disease, infections in unvaccinated and immune deficient patients…”
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