Search Results - "von Baby, Becca"
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Impact of novel pan-RAS inhibitors on efficacy and resistance to AMG-510 and MRTX-1133 in pancreatic cancer cell lines
Published in Journal of clinical oncology (01-06-2023)“…4155 Background: Mutant-activated RAS genes are the most frequently mutated gene family associated with cancer (almost 30% of all cancers contain a mutant RAS…”
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Abstract 3930: Chemoprevention of metastatic colon cancer by a novel small molecule
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Introduction: Colon cancer is a one of the leading cause of death in both men and women. Metastatic colon cancer is responsible for mortality due to…”
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Abstract 3097: Chemo prevention effect of Withaferin A, a natural compound, on mouse models of colorectal carcinogenesis
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Introduction: Colorectal cancer (CRC) is the most common cancer and one of the leading causes of cancer-related deaths in United States as well as…”
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Abstract 4894: Identification of small molecules for the prevention and treatment of colon cancer
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Metastatic colon cancer or colorectal cancer (CRC) is associated with poor survival rate which is less than 5% due to chemo resistance. We previously…”
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Abstract 2598: Developing small molecule inhibitors that target androgen receptor signaling in castration-resistant prostate cancer
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract The transcription factor, androgen receptor (AR) is a key driver and plays an important role in prostate cancer. Androgen ablation therapy and…”
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Abstract B005: RAS inhibitors to treat luminal B breast cancer
Published in Molecular cancer research (01-05-2023)“…Abstract Since RAS mutations are rare in Breast Cancer, RAS has not traditionally been considered as an important driver of this disease. However, RAS…”
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Abstract B006: Novel direct RAS inhibitors for pancreatic cancer
Published in Molecular cancer research (01-05-2023)“…Abstract RAS oncogenes are frequently activated by mutations in pancreatic and lung cancer, where they appear to act as driving mutations. This study examines…”
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Targeted delivery of microbial metabolite, urolithin A protects from chemically (DSS or TNBS) induced colitis in pre-clinical models
Published in The Journal of immunology (1950) (01-05-2017)“…Abstract Epidemiological data suggests that consumption of diets rich in phytochemicals are protective in inflammatory bowel diseases (IBDs). However, the…”
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