Search Results - "von Arnim, C."

Efficacy and safety of pharmacotherapy for Alzheimer’s disease and for behavioural and psychological symptoms of dementia in older patients with moderate and severe functional impairments: a systematic review of controlled trials by Seibert, M, Mühlbauer, V, Holbrook, J, Voigt-Radloff, S, Brefka, S, Dallmeier, D, Denkinger, M, Schönfeldt-Lecuona, C, Klöppel, S, von Arnim, C. A. F

“…Background Many patients with Alzheimer's disease (AD) are physically frail or have substantial functional impairments. There is growing evidence that such…”
Get full text

Association of lung function with overall mortality is independent of inflammatory, cardiac, and functional biomarkers in older adults: the ActiFE-study by Weinmayr, Gudrun, Schulz, Holger, Klenk, Jochen, Denkinger, Michael, Duran-Tauleria, Enric, Koenig, Wolfgang, Dallmeier, Dhayana, Rothenbacher, Dietrich

“…Reduced lung function is associated with overall and cardiovascular mortality. Chronic low grade systemic inflammation is linked to impaired lung function and…”
Get full text

Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease by WATABE-RUDOLPH, M, SONG, Z, ATTEMS, J, JELLINGER, K. A, KESTLER, H. A, ARNIM, C. A. F. Von, RUDOLPH, K. L, LAUSSER, L, SCHNACK, C, BEGUS-NAHRMANN, Y, SCHEITHAUER, M.-O, RETTINGER, G, OTTO, M, TUMANI, H, THAI, D. R

“…DNA damage accumulation in brain is associated with the development of Alzheimer disease (AD), but newly identified protein markers of DNA damage have not been…”
Get full text

A novel presenilin1 mutation (Q223R) associated with early onset Alzheimer's disease, dysarthria and spastic paraparesis and decreased Abeta levels in CSF by Uttner, I., Kirchheiner, J., Tumani, H., Mottaghy, F. M., Lebedeva, E., Özer, E., Ludolph, A. C., Huber, R., Von Arnim, C. A. F.

“…Background and purpose:  A novel presenilin1 (PSEN1) mutation associated with dementia and spastic paraplegia in a family with five affected individuals is…”
Get full text

An unbiased, staged, multicentre, validation strategy for Alzheimer's disease CSF tau levels by Petzold, A., Chapman, M.D., Schraen, S., Verwey, N.A., Pasquier, F., Bombois, S., Brettschneider, J., Fox, N.C., von Arnim, C.A.F., Teunissen, C., Pijnenburg, Y., Riepe, M.W., Otto, M., Tumani, H., Scheltens, P., Buee, L., Rossor, M.N.

“…Newly proposed diagnostic criteria for Alzheimer's disease include cerebrospinal fluid (CSF) tau levels as one core supportive criterion. The published high…”
Get full text

Multimorbidity as a predictor for inpatient admission in clinical emergency and acute medicine : Single-center cluster analysis by Grüneberg, E, Fliedner, R, Beißbarth, T, von Arnim, C A F, Blaschke, S

“…Parallel to demographic trends, an increase of multimorbid patients in emergency and acute medicine is prominent. To define easily applicable criteria for the…”
Get full text

Objectively measured physical activity and vitamin D status in older people from Germany by Klenk, Jochen, Rapp, Kilian, Denkinger, Michael, Nagel, Gabriele, Nikolaus, Thorsten, Peter, Richard, Boehm, Bernhard O, Koenig, Wolfgang, Rothenbacher, Dietrich

“…Background To analyse the seasonal relationship of objectively measured physical activity with vitamin D status in older persons from Southern Germany…”
Get full text

Regional selectivity of amyloid mRNA expression and neurotrophins on repetitive inhibition of oxidative phosphorylation by von Arnim, C A F, Hellweg, R, Büchner, M, Huber, R, Riepe, M W

“…Previously we showed that repetitive inhibition of oxidative phosphorylation impairs synaptic transmission and induces overexpression of amyloid precursor…”
Get full text

Strain dependence of receptor regulation on chemical preconditioning in mice hippocampus by von Arnim, C.A.F, Verstege, E, Riepe, M.W

“…While one current focus for studying mechanisms of disease is investigation of transgenic mice confounding effects of the background strain often are…”
Get full text

Lazy Sundays: role of day of the week and reactivity on objectively measured physical activity in older people by Klenk, Jochen, Peter, Raphael Simon, Rapp, Kilian, Dallmeier, Dhayana, Rothenbacher, Dietrich, Denkinger, Michael, Büchele, Gisela, Becker, T, Böhm, B, Scharffetter-Kochanek, K, Stingl, J, Koenig, W, Riepe, M, Peter, R, Geiger, H, Ludolph, A, von Arnim, C, Nagel, G, Weinmayr, G, Steinacker, J M, Laszlo, R

“…The aim of this study was to assess the effect of day of the week and wearing a device (reactivity) on objectively measured physical activity (PA) in older…”
Get full text

Radiosynthesis and evaluation of [11C]BTA-1 and [11C]3'-Me-BTA-1 as potential radiotracers for in vivo imaging of beta-amyloid plaques by Neumaier, B, Deisenhofer, S, Fürst, D, von Arnim, C A F, Thees, S, Buck, A K, Glatting, G, Landwehrmeyer, G B, Krause, B J, Müller, H D, Sommer, C, Reske, S N, Mottaghy, F M

“…To evaluate the in vitro and in vivo characteristics of [N-methyl-(11)C]2-(4'-(methylaminophenyl)-benzothiazole ([(11)C]BTA-1) as well as…”
Get more information

Neuroprotection and neuronal dysfunction upon repetitive inhibition of oxidative phosphorylation by Hellweg, R, Arnim, C.A.F.von, Büchner, M, Huber, R, Riepe, M.W

“…Repetitive inhibition of oxidative phosphorylation is an established model of neurodegeneration. In contrast, a single mild treatment can be…”
Get full text

Short and simple is not always better: limitations of cognitive screening tests by Uttner, I, Wittig, S, von Arnim, C A F, Jäger, M

“…The increasing prevalence of Alzheimer's dementia (AD) and limited resources in outpatient care have encouraged the distribution of cognitive screening tests,…”
Get more information

Maintenance of health and relief for caregivers of elderly with dementia by using "initial case management": experiences from the Lighthouse Project on Dementia, Ulm, ULTDEM-study by Lukas, A, Kilian, R, Hay, B, Muche, R, von Arnim, C A F, Otto, M, Riepe, M, Jamour, M, Denkinger, M D, Nikolaus, T

“…When facing the well-known demographic development with an increasing number of people suffering from dementia, there is a need of programmes to support…”
Get full text

Radiation dosimetry and biodistribution of the beta-amyloid plaque imaging tracer 11C-BTA-1 in humans by Thees, S, Neumaier, B, Glatting, G, Deisenhofer, S, von Arnim, C A F, Reske, S N, Mottaghy, F M

“…[N-methyl-(11)C]2-(4'-(methylaminophenyl)-benzothiazole ((11)C-BTA-1) is a thioflavin-T derivative that has been one of the promising PET tracers for imaging…”
Get more information

Polyneuropathy and monoclonal IgG/IgA gammopathy--differential neurography on the basis of two patient cases by Abler, B, Gdynia, H-J, von Arnim, C A F

“…With higher age, monoclonal gammopathies are more frequently diagnosed as the underlying cause of polyneuropathies. Whereas in approximately one-third of the…”
Get more information

Granulomatous myositis mimicking slowly progressive lower motor neuron disease by Gdynia, Hans-Jürgen, Osterfeld, N, Dorst, J, Ludolph, A C, von Arnim, C A, Sperfeld, A-D

“…Here we illustrate a 74-year-old patient presenting with clinical signs of slowly progressive motor neuron disease. After electromyography demonstrated…”
Get more information

Diagnosis and differential diagnosis of granulomatous myositis by Gdynia, H-J, Mogel, H, Kühnlein, P, Dorst, J, Osterfeld, N, von Arnim, C A, Sperfeld, A-D

“…Granulomatous myositis is a rare neuromuscular disorder histologically characterized by the development of endomyseal and/or perimyseal granulomas. Clinical…”
Get full text

Mechanisms of hypoxic tolerance in presymptomatic APP23 transgenic mice by von Arnim, C.A.F., Verstege, E., Etrich, S.M., Riepe, M.W.

“…In the B6-Tg (ThylAPP)23Sdz (APP23tg) transgenic mouse model of Alzheimer's disease hypoxic tolerance is impaired prior to amyloid deposition. We therefore…”
Get full text

Gender-dependent hypoxic tolerance mediated via gender-specific mechanisms by von Arnim, C.A.F., Etrich, S.M., Timmler, M., Riepe, M.W.

“…Primary hypoxic tolerance and preconditioning are gender dependent and modulated in females during the estrus cycle. The underlying mechanisms, however, remain…”
Get full text