Search Results - "von der Grün, Jens"

Patient recruitment into clinical studies of solid malignancies during the COVID-19 pandemic in a tertiary cancer center by der Grün, Jens von, Ahmadsei, Maiwand, Breyer, Isabel, Britschgi, Christian, Eberli, Daniel, Hermanns, Thomas, Mangana, Joanna, Petrowsky, Henrik, Ramelyte, Egle, Roth, Patrick, Schär, Gabriel, Opitz, Isabelle, Weller, Michael, Wicki, Andreas, Witzel, Isabell, Balermpas, Panagiotis, Guckenberger, Matthias

“…•Assessment of clinical trial activities during the COVID-19 pandemic•No differences between the organ specific subunits and study characteristics•Data showed…”
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Chemoradiotherapy as Definitive Treatment for Elderly Patients with Head and Neck Cancer by Rödel, Claus, Ghanaati, Shahram, Stöver, Timo, Martin, Daniel, Müller von der Grün, Jens, Balermpas, Panagiotis

“…Background. With the aging population and a rising incidence of squamous cell carcinoma of the head and neck (SCCHN), there is an emerging need for developing…”
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A Novel 2-Metagene Signature to Identify High-Risk HNSCC Patients amongst Those Who Are Clinically at Intermediate Risk and Are Treated with PORT by Patil, Shivaprasad, Linge, Annett, Hiepe, Hannah, Grosser, Marianne, Lohaus, Fabian, Gudziol, Volker, Kemper, Max, Nowak, Alexander, Haim, Dominik, Tinhofer, Inge, Budach, Volker, Guberina, Maja, Stuschke, Martin, Balermpas, Panagiotis, Grün, Jens von der, Schäfer, Henning, Grosu, Anca-Ligia, Abdollahi, Amir, Debus, Jürgen, Ganswindt, Ute, Belka, Claus, Pigorsch, Steffi, Combs, Stephanie E, Boeke, Simon, Zips, Daniel, Jöhrens, Korinna, Baretton, Gustavo B, Baumann, Michael, Krause, Mechthild, Löck, Steffen, On Behalf Of The Dktk-Rog

“…(1) Background: Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) who are biologically at high risk for the development of…”
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Repeated in-field radiosurgery for locally recurrent brain metastases: Feasibility, results and survival in a heavily treated patient cohort by Balermpas, Panagiotis, Stera, Susanne, Müller von der Grün, Jens, Loutfi-Krauss, Britta, Forster, Marie-Thérèse, Wagner, Marlies, Keller, Christian, Rödel, Claus, Seifert, Volker, Blanck, Oliver, Wolff, Robert

“…Stereotactic radiosurgery (SRS) is an established primary treatment for newly diagnosed brain metastases with high local control rates. However, data about…”
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Risk stratification by anamnesis increases SARS-CoV-2 test efficiency in cancer patients by Arnold, Christian Cornelius, von der Grün, Jens, Brekner, Mark Christoph, Licher, Jörg, Fokas, Emmanouil, Rödel, Claus, Fleischmann, Maximilian

“…Purpose To evaluate the impact of testing asymptomatic cancer patients, we analyzed all tests for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)…”
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Multitask Learning with Convolutional Neural Networks and Vision Transformers Can Improve Outcome Prediction for Head and Neck Cancer Patients by Starke, Sebastian, Zwanenburg, Alex, Leger, Karoline, Lohaus, Fabian, Linge, Annett, Kalinauskaite, Goda, Tinhofer, Inge, Guberina, Nika, Guberina, Maja, Balermpas, Panagiotis, Grün, Jens von der, Ganswindt, Ute, Belka, Claus, Peeken, Jan C, Combs, Stephanie E, Boeke, Simon, Zips, Daniel, Richter, Christian, Troost, Esther G. C, Krause, Mechthild, Baumann, Michael, Löck, Steffen

“…Neural-network-based outcome predictions may enable further treatment personalization of patients with head and neck cancer. The development of neural networks…”
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Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in locally advanced head and neck cancer by Hecht, Markus, Eckstein, Markus, Rutzner, Sandra, von der Grün, Jens, Illmer, Thomas, Klautke, Gunther, Laban, Simon, Hautmann, Matthias G, Brunner, Thomas B, Tamaskovics, Bálint, Hinke, Axel, Zhou, Jian-Guo, Frey, Benjamin, Donaubauer, Anna-Jasmina, Becker, Ina, Semrau, Sabine, Hartmann, Arndt, Balermpas, Panagiotis, Budach, Wilfried, Gaipl, Udo S, Iro, Heinrich, Gostian, Antoniu-Oreste, Fietkau, Rainer

“…PurposeThe first aim of the trial is to study feasibility of combined programmed death protein ligand 1/cytotoxic T-lymphocyte-associated protein 4 inhibition…”
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Comprehensive Analysis of Tumour Sub-Volumes for Radiomic Risk Modelling in Locally Advanced HNSCC by Leger, Stefan, Zwanenburg, Alex, Leger, Karoline, Lohaus, Fabian, Linge, Annett, Schreiber, Andreas, Kalinauskaite, Goda, Tinhofer, Inge, Guberina, Nika, Guberina, Maja, Balermpas, Panagiotis, von der Grün, Jens, Ganswindt, Ute, Belka, Claus, Peeken, Jan C., Combs, Stephanie E., Boeke, Simon, Zips, Daniel, Richter, Christian, Krause, Mechthild, Baumann, Michael, Troost, Esther G.C., Löck, Steffen

“…Imaging features for radiomic analyses are commonly calculated from the entire gross tumour volume (GTVentire). However, tumours are biologically complex and…”
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Implementation of Double Immune Checkpoint Blockade Increases Response Rate to Induction Chemotherapy in Head and Neck Cancer by Semrau, Sabine, Gostian, Antoniu-Oreste, Traxdorf, Maximilian, Eckstein, Markus, Rutzner, Sandra, von der Grün, Jens, Illmer, Thomas, Hautmann, Matthias, Klautke, Gunther, Laban, Simon, Brunner, Thomas, Tamaskovics, Bálint, Frey, Benjamin, Zhou, Jian-Guo, Geppert, Carol-Immanuel, Hartmann, Arndt, Balermpas, Panagiotis, Budach, Wilfried, Gaipl, Udo, Iro, Heinrich, Fietkau, Rainer, Hecht, Markus

“…To determine whether a single dose of double immune checkpoint blockade (induction chemoimmunotherapy (ICIT)) adds benefit to induction single-cycle platinum…”
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Diagnostic and treatment modalities for patients with cervical lymph node metastases of unknown primary site - current status and challenges by Müller von der Grün, Jens, Tahtali, Aykut, Ghanaati, Shahram, Rödel, Claus, Balermpas, Panagiotis

“…This review aims to provide a comprehensive overview of the literature and elucidate open questions for future clinical trials concerning diagnostics and…”
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2D and 3D convolutional neural networks for outcome modelling of locally advanced head and neck squamous cell carcinoma by Starke, Sebastian, Leger, Stefan, Zwanenburg, Alex, Leger, Karoline, Lohaus, Fabian, Linge, Annett, Schreiber, Andreas, Kalinauskaite, Goda, Tinhofer, Inge, Guberina, Nika, Guberina, Maja, Balermpas, Panagiotis, von der Grün, Jens, Ganswindt, Ute, Belka, Claus, Peeken, Jan C., Combs, Stephanie E., Boeke, Simon, Zips, Daniel, Richter, Christian, Troost, Esther G. C., Krause, Mechthild, Baumann, Michael, Löck, Steffen

“…For treatment individualisation of patients with locally advanced head and neck squamous cell carcinoma (HNSCC) treated with primary radiochemotherapy, we…”
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MRI-based radiomics for predicting histology in malignant salivary gland tumors: methodology and “proof of principle” by Khodabakhshi, Zahra, Motisi, Laura, Bink, Andrea, Broglie, Martina A., Rupp, Niels J., Fleischmann, Maximilian, von der Grün, Jens, Guckenberger, Matthias, Tanadini-Lang, Stephanie, Balermpas, Panagiotis

“…Defining the exact histological features of salivary gland malignancies before treatment remains an unsolved problem that compromises the ability to tailor…”
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Targeted Therapies and Immune-Checkpoint Inhibition in Head and Neck Squamous Cell Carcinoma: Where Do We Stand Today and Where to Go? by von der Grün, Jens, Rödel, Franz, Brandts, Christian, Fokas, Emmanouil, Guckenberger, Matthias, Rödel, Claus, Balermpas, Panagiotis

“…With an increased understanding of the tumor biology of squamous cell carcinoma of the head and neck (SCCHN), targeted therapies have found their way into the…”
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Patterns of care analysis for salivary gland cancer: a survey within the German Society of Radiation Oncology (DEGRO) and recommendations for daily practice by von der Grün, Jens, Rödel, Claus, Semrau, Sabine, Balermpas, Panagiotis, Martin, Daniel, Fietkau, Rainer, Haderlein, Marlen

“…Background Salivary gland cancer (SGC) is rare and a heterogeneous type of cancer. Prospective randomized trials are lacking. No guideline focusing on standard…”
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Association between spatial distribution of leukocyte subsets and clinical presentation of head and neck squamous cell carcinoma by Netzer, Christoph, von Arps-Aubert, Vanessa, Mačinković, Igor, von der Grün, Jens, Küffer, Stefan, Ströbel, Philipp, von Knethen, Andreas, Weigert, Andreas, Beutner, Dirk

“…Interactions between tumor cells and cells in the microenvironment contribute to tumor development and metastasis. The spatial arrangement of individual cells…”
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Leukocytosis and neutrophilia as independent prognostic immunological biomarkers for clinical outcome in the CAO/ARO/AIO‐04 randomized phase 3 rectal cancer trial by Diefenhardt, Markus, Hofheinz, Ralf‐Dieter, Martin, Daniel, Beißbarth, Tim, Arnold, Dirk, Hartmann, Arndt, Grün, Jens, Grützmann, Robert, Liersch, Torsten, Ströbel, Philipp, Grabenbauer, Gerhard G., Rieger, Michael, Fietkau, Rainer, Graeven, Ullrich, Weitz, Jürgen, Folprecht, Gunar, Ghadimi, Michael, Rödel, Franz, Rödel, Claus, Fokas, Emmanouil

“…Peripheral blood leukocytosis and neutrophilia reflect cancer inflammation and have been proposed as prognostic immunological biomarkers in various…”
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Sarcopenia Is Associated With Hematologic Toxicity During Chemoradiotherapy in Patients With Anal Carcinoma by Martin, Daniel, von der Grün, Jens, Rödel, Claus, Fokas, Emmanouil

“…Sarcopenia, defined as a loss of muscle mass and quality, has been associated with impaired oncological outcome and treatment toxicities in several…”
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Management of anal cancer patients - a pattern of care analysis in German-speaking countries by Martin, Daniel, von der Grün, Jens, Rödel, Claus, Fokas, Emmanouil

“…Radiotherapy dose and target volume prescriptions for anal squamous cell carcinoma (ASCC) vary considerably in daily practice and guidelines, including those…”
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Safety and efficacy of single cycle induction treatment with cisplatin/docetaxel/ durvalumab/tremelimumab in locally advanced HNSCC: first results of CheckRad-CD8 by Hecht, Markus, Gostian, Antoniu Oreste, Eckstein, Markus, Rutzner, Sandra, von der Grün, Jens, Illmer, Thomas, Hautmann, Matthias G, Klautke, Gunther, Laban, Simon, Brunner, Thomas, Hinke, Axel, Becker, Ina, Frey, Benjamin, Semrau, Sabine, Geppert, Carol I, Hartmann, Arndt, Balermpas, Panagiotis, Budach, Wilfried, Gaipl, Udo S, Iro, Heinrich, Fietkau, Rainer

“…BackgroundTo determine safety and efficacy of single cycle induction treatment with cisplatin/docetaxel and durvalumab/tremelimumab in stage III-IVB head and…”
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Integrated radiogenomics analyses allow for subtype classification and improved outcome prognosis of patients with locally advanced HNSCC by Rabasco Meneghetti, Asier, Zwanenburg, Alex, Linge, Annett, Lohaus, Fabian, Grosser, Marianne, Baretton, Gustavo B., Kalinauskaite, Goda, Tinhofer, Ingeborg, Guberina, Maja, Stuschke, Martin, Balermpas, Panagiotis, von der Grün, Jens, Ganswindt, Ute, Belka, Claus, Peeken, Jan C., Combs, Stephanie E., Böke, Simon, Zips, Daniel, Troost, Esther G. C., Krause, Mechthild, Baumann, Michael, Löck, Steffen

“…Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) may benefit from personalised treatment, requiring biomarkers that characterize…”
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