Search Results - "von Hofsten, Jonas"
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Flagella-mediated secretion of a novel Vibrio cholerae cytotoxin affecting both vertebrate and invertebrate hosts
Published in Communications biology (01-01-2018)“…Using Caenorhabditis elegans as an infection host model for Vibrio cholerae predator interactions, we discovered a bacterial cytotoxin, MakA, whose function as…”
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Generating transparent zebrafish: a refined method to improve detection of gene expression during embryonic development
Published in Marine biotechnology (New York, N.Y.) (01-11-2001)“…In zebrafish (Danio rerio) pigmentation is initiated during embryogenesis and begins in the retinal epithelium and in the melanophores. The pigment cells…”
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Pax7 is required for establishment of the xanthophore lineage in zebrafish embryos
Published in Molecular biology of the cell (01-06-2016)“…The pigment pattern of many animal species is a result of the arrangement of different types of pigment-producing chromatophores. The zebrafish has three…”
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Genetic compensation between Pax3 and Pax7 in zebrafish appendicular muscle formation
Published in Developmental dynamics (01-09-2022)“…Background Migrating muscle progenitors delaminate from the somite and subsequently form muscle tissue in distant anatomical regions such as the paired…”
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Molecular cloning and characterization of a nuclear androgen receptor activated by 11-ketotestosterone
Published in Reproductive biology and endocrinology (17-08-2005)“…Although 11-ketotestosterone is a potent androgen and induces male secondary sex characteristics in many teleosts, androgen receptors with high binding…”
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The zebrafish HGF receptor met controls migration of myogenic progenitor cells in appendicular development
Published in PloS one (09-07-2019)“…The hepatocyte growth factor receptor C-met plays an important role in cellular migration, which is crucial for many developmental processes as well as for…”
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A new G-quadruplex-specific photosensitizer inducing genome instability in cancer cells by triggering oxidative DNA damage and impeding replication fork progression
Published in Nucleic acids research (07-07-2023)“…Abstract Photodynamic therapy (PDT) ideally relies on the administration, selective accumulation and photoactivation of a photosensitizer (PS) into diseased…”
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fhl2b mediates extraocular muscle protection in zebrafish models of muscular dystrophies and its ectopic expression ameliorates affected body muscles
Published in Nature communications (02-03-2024)“…In muscular dystrophies, muscle fibers loose integrity and die, causing significant suffering and premature death. Strikingly, the extraocular muscles (EOMs)…”
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Desmin gene expression is not ubiquitous in all upper airway myofibers and the pattern differs between healthy and sleep apnea subjects
Published in European journal of medical research (03-04-2024)“…Desmin is a major cytoskeletal protein considered ubiquitous in mature muscle fibers. However, we earlier reported that a subgroup of muscle fibers in the soft…”
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10
Differential regulation of myosin heavy chains defines new muscle domains in zebrafish
Published in Molecular biology of the cell (15-04-2014)“…Numerous muscle lineages are formed during myogenesis within both slow- and fast-specific cell groups. In this study, we show that six fast muscle-specific…”
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A balance of BMP and notch activity regulates neurogenesis and olfactory nerve formation
Published in PloS one (23-02-2011)“…Although the function of the adult olfactory system has been thoroughly studied, the molecular mechanisms regulating the initial formation of the olfactory…”
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Zebrafish sex determination and differentiation: involvement of FTZ-F1 genes
Published in Reproductive biology and endocrinology (10-11-2005)“…Sex determination is the process deciding the sex of a developing embryo. This is usually determined genetically; however it is a delicate process, which in…”
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Absence of Desmin in Myofibers of the Zebrafish Extraocular Muscles
Published in Translational vision science & technology (01-09-2020)“…To study the medial rectus (MR) muscle of zebrafish ( ) with respect to the pattern of distribution of desmin and its correlation to distinct types of…”
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Six1 regulates proliferation of Pax7+ muscle progenitors in zebrafish
Published in Journal of cell science (01-01-2013)“…In the embryonic zebrafish, skeletal muscle fibres are formed from muscle progenitors in the paraxial mesoderm. The embryonic myotome is mostly constituted of…”
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Opposing Fgf and Bmp activities regulate the specification of olfactory sensory and respiratory epithelial cell fates
Published in Development (Cambridge) (15-05-2010)“…The olfactory sensory epithelium and the respiratory epithelium are derived from the olfactory placode. However, the molecular mechanisms regulating the…”
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P53 mediated regulation of metallothionein transcription in breast cancer cells
Published in Journal of cellular biochemistry (15-12-2007)“…Recent studies have shown that only breast cancer epithelial cells with intact p53 can induce metallothionein (MT) synthesis after exposure to metals. In this…”
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Expression and Regulation of Fushi Tarazu Factor-1 and Steroidogenic Genes During Reproduction in Arctic Char (Salvelinus alpinus)
Published in Biology of reproduction (01-10-2002)“…Teleost fushi tarazu factor-1 (FTZ-F1) is a potential regulator of steroidogenesis. The present study shows sex-specific regulation of Arctic char fushi tarazu…”
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Molecular Characterization and Expression Pattern of Zona Pellucida Proteins in Gilthead Seabream (Sparus aurata)1
Published in Biology of reproduction (01-11-2006)“…The developing oocyte is surrounded by an acellular envelope that is composed of 2–4 isoforms of zona pellucida (ZP) proteins. The ZP proteins comprise the…”
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Expression and Regulation of Fushi Tarazu Factor-1 and Steroidogenic Genes During Reproduction in Arctic Char (Salvelinus alpinus)1
Published in Biology of reproduction (01-10-2002)“…Teleost fushi tarazu factor-1 (FTZ-F1) is a potential regulator of steroidogenesis. The present study shows sex-specific regulation of Arctic char fushi tarazu…”
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Obscurin Maintains Myofiber Identity in Extraocular Muscles
Published in Investigative ophthalmology & visual science (01-02-2024)“…The cytoskeleton of the extraocular muscles (EOMs) is significantly different from that of other muscles. We aimed to investigate the role of obscurin, a…”
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