Search Results - "von, Scheidt M"

Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes by Li, Ling, Chen, Zhifen, von Scheidt, Moritz, Li, Shuangyue, Steiner, Andrea, Güldener, Ulrich, Koplev, Simon, Ma, Angela, Hao, Ke, Pan, Calvin, Lusis, Aldons J., Pang, Shichao, Kessler, Thorsten, Ermel, Raili, Sukhavasi, Katyayani, Ruusalepp, Arno, Gagneur, Julien, Erdmann, Jeanette, Kovacic, Jason C., Björkegren, Johan L. M., Schunkert, Heribert

“…The majority of risk loci identified by genome-wide association studies (GWAS) are in non-coding regions, hampering their functional interpretation. Instead,…”
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ADAMTS-7 Modulates Atherosclerotic Plaque Formation by Degradation of TIMP-1 by Sharifi, M. Amin, Wierer, Michael, Dang, Tan An, Milic, Jelena, Moggio, Aldo, Sachs, Nadja, von Scheidt, Moritz, Hinterdobler, Julia, Müller, Philipp, Werner, Julia, Stiller, Barbara, Aherrahrou, Zouhair, Erdmann, Jeanette, Zaliani, Andrea, Graettinger, Mira, Reinshagen, Jeanette, Gul, Sheraz, Gribbon, Philip, Maegdefessel, Lars, Bernhagen, Jürgen, Sager, Hendrik B., Mann, Matthias, Schunkert, Heribert, Kessler, Thorsten

“…BACKGROUND: The ADAMTS7 locus was genome-wide significantly associated with coronary artery disease. Lack of the ECM (extracellular matrix) protease ADAMTS-7…”
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Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism by von Scheidt, Moritz, Zhao, Yuqi, de Aguiar Vallim, Thomas Q., Che, Nam, Wierer, Michael, Seldin, Marcus M., Franzén, Oscar, Kurt, Zeyneb, Pang, Shichao, Bongiovanni, Dario, Yamamoto, Masayuki, Edwards, Peter A., Ruusalepp, Arno, Kovacic, Jason C., Mann, Matthias, Björkegren, Johan L.M., Lusis, Aldons J., Yang, Xia, Schunkert, Heribert

“…Coronary artery disease (CAD) is a multifactorial condition with both genetic and exogenous causes. The contribution of tissue-specific functional networks to…”
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Vascular tissue specific miRNA profiles reveal novel correlations with risk factors in coronary artery disease by Bauer, S., Vilne, B., Neiburga, K.D., Schunkert, H., Von Scheidt, M.

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Identification of the transcription factor ATF3 as a new regulator of the LDLR by Eigenmann, J., Bauer, S., Fleig, J., Zhao, Y., Schunkert, H., Von Scheidt, M.

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Comparative outcomes of drug-coated balloon angioplasty versus second-generation drug-eluting stent for in-stent restenosis: a real-world data analysis by Krefting, J, Krueger, N, Graesser, C, Schmieder, R, Starnecker, F, Kufner, S, Cassese, S, Kastrati, A, Schunkert, H, Von Scheidt, M, Wiebe, J

“…Abstract Background Coronary in-stent restenosis (ISR) poses a significant challenge in interventional cardiology, with optimal treatment strategies being the…”
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From bench to bedside and back to bench: investigating the role of platelet heterogeneity in coronary artery disease by Bongiovanni, D, Kirmes, K, Han, J, Bloxham, C, Klug, M, Viggiani, G, Kuehne, S, List, M, Chiarito, M, Von Scheidt, M, Condorelli, G, Raake, P, Bernlochner, I

“…Abstract Background/Introduction Platelets exhibit considerable heterogeneity in RNA content, size, and thrombogenicity. Our preliminary investigation of the…”
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The orchestration of coding and non-coding genes at the CDH13 locus in coronary artery disease by Chen, Z, Li, S, Li, L, Diagel, A, Moggio, A, Li, Z, Song, X, Sager, H, Boon, R, Maegdefessel, L, Kessler, T, Von Scheidt, M, Bjorkegren, J L M, Maliheh, N J, Schunkert, H

“…Abstract Background The CDH13 locus was associated with coronary artery disease (CAD) by genome-wide association studies (GWAS). However, the causal gene(s)…”
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Man-machine interaction-based phenotyping preprocedurally identifies patients with severe aortic stenosis, who will not recover from cardiac damage following transcatheter aortic valve replacement by Rippen, E, Lachmann, M, Schuster, T, Xhepa, E, Von Scheidt, M, Harmsen, G, Yuasa, S, Kupatt, C, Joner, M, Laugwitz, K L

“…Abstract Background Severe aortic stenosis (AS) can lead to left heart dysfunction, pulmonary hypertension (PH), and eventually right heart failure. Clinical…”
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Sub-phenotyping of patients with severe aortic stenosis undergoing transcatheter aortic valve replacement by unsupervised agglomerative clustering of echocardiographic and hemodynamic data by Lachmann, M, Rippen, E, Schuster, T, Xhepa, E, Von Scheidt, M, Harmsen, G, Yuasa, S, Laugwitz, K L, Kupatt, C, Joner, M

“…Abstract Background Severe aortic stenosis (AS) can trigger a deleterious cascade of impairments including left heart dysfunction, pulmonary hypertension (PH),…”
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Reticulated platelet mass cytometry reveals unexplored therapeutic targets in patients with chronic coronary syndrome by Bongiovanni, D, Klug, M, Lazareva, O, Kirmes, K, Biasi, M, Okrojek, R, Gosetti, R, Manz, Q, Arend, L, Bernett, J, Von Scheidt, M, Condorelli, G, Laugwitz, K L, List, M, Bernlochner, I

“…Abstract Background Reticulated platelets (RPs) are young, hyper-reactive thrombocytes that contain more RNA compared with mature platelets (MPs). The…”
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Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes (vol 117, 6, 2022) by Li, L, Chen, Z, von, Scheidt M, Li, S, Steiner, A, Gueldener, U, Koplev, S, Ma, A, Hao, K, Pan, C

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P1844The transcription factor MAFF regulates an atherosclerosis relevant gene network by Von Scheidt, M, Zhao, Y, De Aguiar Vallim, T Q, Che, N, Franzen, O, Kurt, Z, Yamamoto, M, Edwards, P A, Ruusalepp, A, Kovacic, J, Bjorkegren, J L M, Lusis, A J, Yang, X, Schunkert, H

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Publisher Correction: Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes by Li, Ling, Chen, Zhifen, von Scheidt, Moritz, Li, Shuangyue, Steiner, Andrea, Güldener, Ulrich, Koplev, Simon, Ma, Angela, Hao, Ke, Pan, Calvin, Lusis, Aldons J., Pang, Shichao, Kessler, Thorsten, Ermel, Raili, Sukhavasi, Katyayani, Ruusalepp, Arno, Gagneur, Julien, Erdmann, Jeanette, Kovacic, Jason C., Björkegren, Johan L. M., Schunkert, Heribert

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Vascular Tissue Specific miRNA Profiles Reveal Novel Correlations with Risk Factors in Coronary Artery Disease by Neiburga, Katrīna D, Vilne, Baiba, Bauer, Sabine, Bongiovanni, Dario, Ziegler, Tilman, Lachmann, Mark, Wengert, Simon, Hawe, Johann S, Güldener, Ulrich, Westerlund, Annie M, Li, Ling, Pang, Shichao, Yang, Chuhua, Saar, Kathrin, Huebner, Norbert, Maegdefessel, Lars, DigiMed Bayern Consortium, Lange, Rüdiger, Krane, Markus, Schunkert, Heribert, von Scheidt, Moritz

“…Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Non-coding RNAs have already been linked to CVD development and…”
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Identification of the Transcription Factor ATF3 as a Direct and Indirect Regulator of the LDLR by Bauer, Sabine, Eigenmann, Jana, Zhao, Yuqi, Fleig, Julia, Hawe, Johann S, Pan, Calvin, Bongiovanni, Dario, Wengert, Simon, Ma, Angela, Lusis, Aldons J, Kovacic, Jason C, Björkegren, Johan L M, Maegdefessel, Lars, Schunkert, Heribert, von Scheidt, Moritz

“…Coronary artery disease (CAD) is a complex, multifactorial disease caused, in particular, by inflammation and cholesterol metabolism. At the molecular level,…”
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The transcription factor MAFF regulates an atherosclerosis relevant gene network by Von Scheidt, M, Zhao, Y, Vallim, TQD, Che, N, Franzen, O, Kurt, Z, Yamamoto, M, Edwards, PA, Ruusalepp, A, Kovacic, J, Bjorkegren, JLM, Lusis, AJ, Yang, X, Schunkert, H

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D-Dimer Predicts Disease Severity but Not Long-Term Prognosis in Acute Pulmonary Embolism by Geissenberger, Fabian, Schwarz, Florian, Probst, Michael, Haberl, Sabine, Gruetzner, Stefanie, Kroencke, Thomas, von Scheidt, Wolfgang, Berghaus, Thomas M.

“…D-dimer might be correlated with prognosis in pulmonary embolism (PE). The predictive value of plasma D-dimer for disease severity and survival was…”
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Usefulness of Iron Deficiency Correction in Management of Patients with Heart Failure (From the RAID-HF Registry) by Wienbergen, Harm, MD, Pfister, Otmar, MD, Hochadel, Matthias, PhD, Michel, Stephan, Bruder, Oliver, MD, Remppis, Björn Andrew, MD, Maeder, Micha, MD, Strasser, Ruth, MD, von Scheidt, Wolfgang, MD, Pauschinger, Matthias, MD, Senges, Jochen, MD, Hambrecht, Rainer, MD

“…Abstract Iron deficiency (ID) has been identified as an important comorbidity in patients with heart failure (HF). Intravenous iron therapy reduced symptoms…”
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Presenting symptoms of myocardial infarction predict short- and long-term mortality: The MONICA/KORA Myocardial Infarction Registry by Kirchberger, Inge, PhD, MPH, Heier, Margit, MD, Kuch, Bernhard, MD, von Scheidt, Wolfgang, MD, Meisinger, Christa, MD, MPH

“…Background It is unknown whether clinical outcomes differ with specific symptoms of an acute myocardial infarction (AMI). The objective of this study was to…”
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