Search Results - "van der Zanden, Esmerij P"

Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway by de Jonge, Wouter J, van der Zanden, Esmerij P, The, Frans O, Bijlsma, Maarten F, van Westerloo, David J, Bennink, Roelof J, Berthoud, Hans-Rudolf, Uematsu, Satoshi, Akira, Shizuo, van den Wijngaard, Rene M, Boeckxstaens, Guy E

“…Acetylcholine released by efferent vagus nerves inhibits macrophage activation. Here we show that the anti-inflammatory action of nicotinic receptor activation…”
Get full text

Unphosphorylated STAT3 modulates alpha7 nicotinic receptor signaling and cytokine production in sepsis by Peña, Geber, Cai, Bolin, Liu, Jun, van der Zanden, Esmerij P., Deitch, Edwin A., de Jonge, Wouter J., Ulloa, Luis

“…The role of STAT3 in infectious diseases remains undetermined, in part because unphosphorylated STAT3 has been considered an inactive protein. Here, we report…”
Get full text

Vagus Nerve Activity Augments Intestinal Macrophage Phagocytosis via Nicotinic Acetylcholine Receptor α4β2 by van der Zanden, Esmerij P, Snoek, Susanne A, Heinsbroek, Sigrid E, Stanisor, Oana I, Verseijden, Caroline, Boeckxstaens, Guy E, Peppelenbosch, Maikel P, Greaves, David R, Gordon, Siamon, De Jonge, Wouter J

“…Background & Aims The vagus nerve negatively regulates macrophage cytokine production via the release of acetylcholine (ACh) and activation of nicotinic…”
Get full text

Selective α7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis by Snoek, Susanne A, Verstege, Marleen I, van der Zanden, Esmerij P, Deeks, Nigel, Bulmer, David C, Skynner, Michael, Lee, Kevin, te Velde, Anje A, Boeckxstaens, Guy E, de Jonge, Wouter J

“…Background and purpose:  In various models vagus nerve activation has been shown to ameliorate intestinal inflammation, via nicotinic acetylcholine receptors…”
Get full text

Nicotinic acetylcholine receptor expression and susceptibility to cholinergic immunomodulation in human monocytes of smoking individuals by van der Zanden, Esmerij P, Hilbers, Francisca W, Verseijden, Caroline, van den Wijngaard, Rene M, Skynner, Mike, Lee, Kevin, Ulloa, Luis, Boeckxstaens, Guy E, de Jonge, Wouter J

“…Smoking is generally accepted as a factor that affects the disease course in inflammatory bowel disease patients. Whether these effects can be contributed to…”
Get more information

The α7 nicotinic acetylcholine receptor on fibroblast‐like synoviocytes and in synovial tissue from rheumatoid arthritis patients: A possible role for a key neurotransmitter in synovial inflammation by Maanen, Marjolein A. Van, Stoof, Susanne P., Zanden, Esmerij P. Van Der, Jonge, Wouter J. De, Janssen, Richard A., Fischer, David F., Vandeghinste, Nick, Brys, Reginald, Vervoordeldonk, Margriet J., Tak, Paul P.

“…Objective Recent studies have suggested an important role for neurotransmitters as modulators of inflammation. Therefore, we undertook this study to…”
Get full text

Comparison of Adalimumab Serum Drug Levels When Delivered by Pen Versus Syringe in Patients With Inflammatory Bowel Disease. An International, Multicentre Cohort Analysis by Little, Robert D, Chu, Isabel E, van der Zanden, Esmerij P, Flanagan, Emma, Bell, Sally J, Gibson, Peter R, Sparrow, Miles P, Shelton, Edward, Connor, Susan J, Roblin, Xavier, Ward, Mark G

“…Abstract Background Adalimumab is administered via a pre-filled syringe or spring-loaded pen. In a previous study in Crohn’s disease, higher drug levels were…”
Get full text

725 Cholinergic Agonists Attenuate Inflammation in Macrophages via Interaction With Neuropeptides by van der Zanden, Esmerij P, Michel, Klaus, Schemann, Michael, Boeckxstaens, Guy E, de Jonge, Wouter

Get full text

T2044 Vagus Nerve Released Acetylcholine Can Inhibit Intestinal Inflammation via Cross Talk With Vasoactive Intestinal Peptide by van der Zanden, Esmerij P, Cailotto, Cathy, Nijhuis, Laurens, Boeckxstaens, Guy E, de Jonge, Wouter

Get full text

W1687 Nicotine Enhances Phagocytosis in Macrophages via Recruitment of Dynamin-2 to the Phagocytic Cup by van der Zanden, Esmerij P, Boeckxstaens, Guy E, de Jonge, Wouter

Get full text

M1631 Acetylcholine Enhances Macrophage Phagocytosis and Induces Inflammatory Anergy via Distinct nAChR Subunits by van der Zanden, Esmerij P, Boeckxstaens, Guy E, Lee, Kevin, de Jonge, Wouter

Get full text

W1375 Nicotine Reduces TLR2 and NOD2, But Not TLR4- Induced NF-KappaB Activation in Mouse Spleen Macrophages by van der Zanden, Esmerij P, Boeckxstaens, Guy E, de Jonge, Wouter

Get full text

864 Which Clinical Symptoms Reflect Postoperative Recovery of Gastrointestinal Motility? by van Bree, Sjoerd, Nijhuis, Laurens, Vlug, Malaika, Bemelman, Willem, de Jonge, Wouter, Snoek, Susanne A, van der Zanden, Esmerij P, The, Frans O, Hollmann, Markus W, Bennink, Roelof J, Boeckxstaens, Guy E

Get full text

S1018 The Effect of Laparoscopy and/or Fast Track Multimodal Management on Postoperative Gastrointestinal Motility After Colonic Surgery by van Bree, Sjoerd, Vlug, Malaika, Bemelman, Willem, Hollmann, Markus W, de Jonge, Wouter, Snoek, Susanne A, van der Zanden, Esmerij P, The, Frans O, Bennink, Roelof J, Boeckxstaens, Guy E

Get full text

139 The Mechanism of Intestinal Barrier Dysfunction Induced by Bowel Manipulation in a Model for Postoperative Ileus by Snoek, Susanne A, Stanisor, Oana I, Hilbers, Francisca W, van Bree, Sjoerd, van der Zanden, Esmerij P, Verseyden, Caroline, Koeman, Anneke, van den Wijngaard, Rene M, Zuurbier, Coert J, Boeckxstaens, Guy E, de Jonge, Wouter

Get full text

45 Vagal Nerve Activity Stimulates Endo- and Phagocytosis in Intestinal and Peritoneal Macrophages Via Nicotinic Acetylcholine Receptor Alpha4/Beta2 in Mice by de Jonge, Wouter, Heinsbroek, Sigrid, van der Zanden, Esmerij P, Snoek, Susanne A, Cailotto, Cathy, Boeckxstaens, Guy E, Greaves, David, Gordon, Siamon

Get full text

Inflammation and Gut Motility; Neural Control of Intestinal Immune Cell Activation by De Jonge, Wouter J, The, Frans O, Zanden, Esmerij P, Wijngaard, René M, Boeckxstaens, Guy E

Get full text

Erratum: Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway by de Jonge, Wouter J, van der Zanden, Esmerij P, The, Frans O, Bijlsma, Maarten F, van Westerloo, David J, Bennink, Roelof J, Berthoud, Hans-Rudolf, Uematsu, Satoshi, Akira, Shizuo, van den Wijngaard, Rene M, Boeckxstaens, Guy E

Get full text

Faster Recovery of Gastrointestinal Transit After Laparoscopy and Fast-Track Care in Patients Undergoing Colonic Surgery by van Bree, Sjoerd, Vlug, Malaika, Bemelman, Willem, Hollmann, Markus, Ubbink, Dirk, Zwinderman, Koos, de Jonge, Wouter, Snoek, Susanne, Bolhuis, Karen, van der Zanden, Esmerij, The, Frans, Bennink, Roel, Boeckxstaens, Guy

“…Background & Aims Postoperative ileus is characterized by delayed gastrointestinal (GI) transit and is a major determinant of recovery after colorectal…”
Get full text

Selective [alpha]7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis by Snoek, Susanne A, Verstege, Marleen I, van der Zanden, Esmerij P, Deeks, Nigel, Bulmer, David C, Skynner, Michael, Lee, Kevin, te Velde, Anje A, Boeckxstaens, Guy E, de Jonge, Wouter J

“…Background and purpose: In various models vagus nerve activation has been shown to ameliorate intestinal inflammation, via nicotinic acetylcholine receptors…”
Get full text