Search Results - "van der Westhuyzen, Deneys R"

Scavenger receptor CD36 expression contributes to adipose tissue inflammation and cell death in diet-induced obesity by Cai, Lei, Wang, Zhen, Ji, Ailing, Meyer, Jason M, van der Westhuyzen, Deneys R

“…The enlarged adipose tissue in obesity is characterized by inflammation, including the recruitment and infiltration of macrophages and lymphocytes. The…”
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SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance by Cai, Lei, Ji, Ailing, de Beer, Frederick C, Tannock, Lisa R, van der Westhuyzen, Deneys R

“…Septic shock results from an uncontrolled inflammatory response, mediated primarily by LPS. Cholesterol transport plays an important role in the host response…”
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Adiponectin Reduces Plasma Triglyceride by Increasing VLDL Triglyceride Catabolism by Qiao, Liping, Zou, Chenhui, van der Westhuyzen, Deneys R, Shao, Jianhua

“…Adiponectin Reduces Plasma Triglyceride by Increasing VLDL Triglyceride Catabolism Liping Qiao 1 , Chenhui Zou 1 , Deneys R. van der Westhuyzen 1 2 and Jianhua…”
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Macrophage SR-BI regulates LPS-induced pro-inflammatory signaling in mice and isolated macrophages by Cai, Lei, Wang, Zhen, Meyer, Jason M., Ji, Ailing, van der Westhuyzen, Deneys R.

“…Scavenger receptor BI (SR-BI), an HDL receptor, plays a key role in reverse cholesterol transport. In mice, disruption of SR-BI results in hypersensitivity to…”
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Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI by Ji, Ailing, Wroblewski, Joanne M., Cai, Lei, de Beer, Maria C., Webb, Nancy R., van der Westhuyzen, Deneys R.

“…To study the mechanisms of hepatic HDL formation, we investigated the roles of ABCA1, ABCG1, and SR-BI in nascent HDL formation in primary hepatocytes isolated…”
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HDL Remodeling During the Acute Phase Response by Jahangiri, Anisa, de Beer, Maria C, Noffsinger, Victoria, Tannock, Lisa R, Ramaiah, Chandrashekar, Webb, Nancy R, van der Westhuyzen, Deneys R, de Beer, Frederick C

“…OBJECTIVE—The purpose of this study was to examine the interactive action of serum amyloid A (SAA), group IIA secretory phospholipase A2 (sPLA2-IIA), and…”
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The ABCG5 ABCG8 Sterol Transporter Opposes the Development of Fatty Liver Disease and Loss of Glycemic Control Independently of Phytosterol Accumulation by Su, Kai, Sabeva, Nadezhda S., Liu, Jingjing, Wang, Yuhuan, Bhatnagar, Saloni, van der Westhuyzen, Deneys R., Graf, Gregory A.

“…ABCG5 and ABCG8 form a complex (G5G8) that opposes the absorption of plant sterols but is also expressed in liver where it promotes the excretion of…”
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Impact of individual acute phase serum amyloid A isoforms on HDL metabolism in mice[S] by Kim, Myung-Hee, de Beer, Maria C., Wroblewski, Joanne M., Charnigo, Richard J., Ji, Ailing, Webb, Nancy R., de Beer, Frederick C., van der Westhuyzen, Deneys R.

“…The acute phase (AP) reactant serum amyloid A (SAA), an HDL apolipoprotein, exhibits pro-inflammatory activities, but its physiological function(s) are poorly…”
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Minimally oxidized LDL inhibits macrophage selective cholesteryl ester uptake and native LDL-induced foam cell formation[S] by Meyer, Jason M., Ji, Ailing, Cai, Lei, van der Westhuyzen, Deneys R.

“…Scavenger receptor-mediated uptake of oxidized LDL (oxLDL) is thought to be the major mechanism of foam cell generation in atherosclerotic lesions. Recent data…”
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Mammalian Wnt3a is Released on Lipoprotein Particles by Neumann, Sylvia, Coudreuse, Damien Y.M, van der Westhuyzen, Deneys R, Eckhardt, Erik R.M, Korswagen, Hendrik C, Schmitz, Gerd, Sprong, Hein

“…Little is known about the release and intercellular transport of Wnt proteins from mammalian cells. Lipoproteins may act as carriers for the intercellular…”
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Impact of serum amyloid A on high density lipoprotein composition and levels by de Beer, Maria C., Webb, Nancy R., Wroblewski, Joanne M., Noffsinger, Victoria P., Rateri, Debra L., Ji, Ailing, van der Westhuyzen, Deneys R., de Beer, Frederick C.

“…Serum amyloid A (SAA) is an acute-phase protein mainly associated with HDL. To study the role of SAA in mediating changes in HDL composition and metabolism…”
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Serum Amyloid A Promotes Cholesterol Efflux Mediated by Scavenger Receptor B-I by van der Westhuyzen, Deneys R., Cai, Lei, de Beer, Maria C., de Beer, Frederick C.

“…Serum amyloid A (SAA) is an acute phase protein whose expression is markedly up-regulated during inflammation and infection. The physiological function of SAA…”
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Syndecan-4 mediates macrophage uptake of group V secretory phospholipase A2-modified LDL by Boyanovsky, Boris B., Shridas, Preetha, Simons, Michael, van der Westhuyzen, Deneys R., Webb, Nancy R.

“…We previously reported that LDL modified by group V secretory phospholipase A2 (GV-LDL) promotes macrophage foam cell formation through a mechanism independent…”
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High-capacity selective uptake of cholesteryl ester from native LDL during macrophage foam cell formation by Meyer, Jason M., Ji, Ailing, Cai, Lei, van der Westhuyzen, Deneys R.

“…Macrophage foam cells are a defining pathologic feature of atherosclerotic lesions. Recent studies have demonstrated that at high concentrations associated…”
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Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI by Sun, Bing, Boyanovsky, Boris B., Connelly, Margery A., Shridas, Preetha, van der Westhuyzen, Deneys R., Webb, Nancy R.

“…Modified forms of LDL, including oxidized low density lipoprotein (OxLDL), contribute to macrophage lipid accumulation in the vessel wall. Despite the…”
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Nascent HDL formation by hepatocytes is reduced by the concerted action of serum amyloid A and endothelial lipase by Wroblewski, Joanne M., Jahangiri, Anisa, Ji, Ailing, de Beer, Frederick C., van der Westhuyzen, Deneys R., Webb, Nancy R.

“…Inflammation is associated with significant decreases in plasma HDL-cholesterol (HDL-C) and apoA-I levels. Endothelial lipase (EL) is known to be an important…”
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SR-BI-mediated High Density Lipoprotein (HDL) Endocytosis Leads to HDL Resecretion Facilitating Cholesterol Efflux by Pagler, Tamara A., Rhode, Sebastian, Neuhofer, Angelika, Laggner, Hildegard, Strobl, Wolfgang, Hinterndorfer, Claudia, Volf, Ivo, Pavelka, Margit, Eckhardt, Erik R.M., van der Westhuyzen, Deneys R., Schütz, Gerhard J., Stangl, Herbert

“…The high density lipoprotein (HDL) receptor, scavenger receptor class B, type I (SR-BI), mediates selective cholesteryl ester uptake from lipoproteins into…”
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Human Serum Amyloid A Protein Inhibits Hepatitis C Virus Entry into Cells by ZHAOHUI CAI, LEI CAN, JIEYUN JIANG, CHANG, Kyung-Soo, VAN DER WESTHUYZEN, Deneys R, GUANGXIANG LUO

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Group V Secretory Phospholipase A2-modified Low Density Lipoprotein Promotes Foam Cell Formation by a SR-A- and CD36-independent Process That Involves Cellular Proteoglycans by Boyanovsky, Boris B., van der Westhuyzen, Deneys R., Webb, Nancy R.

“…Accumulating evidence indicates that secretory phospholipase A2 (sPLA2) enzymes promote atherogenic processes. We have previously showed the presence of Group…”
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High Density Lipoprotein Uptake by Scavenger Receptor SR-BII by Eckhardt, Erik R M, Cai, Lei, Sun, Bing, Webb, Nancy R, van der Westhuyzen, Deneys R

“…Scavenger receptor class B, type I (SR-BI) mediates selective uptake of high density lipoprotein (HDL) lipids. It is unclear whether this process occurs at the…”
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