Search Results - "van der Velden, J"

Do participants in a physical activity program from a Care Sport Connector become healthier? An explorative study from the Netherlands by Smit, E, Leenaars, K E F, Wagemakers, M A E, Bakker, E J, Velden, J van der, Molleman, G R M

“…Care Sport Connectors (CSCs) have been appointed to create a connection between the primary care and physical activity (PA) sectors to stimulate residents who…”
Get full text

The Evolving Landscape of Flowcytometric Minimal Residual Disease Monitoring in B-Cell Precursor Acute Lymphoblastic Leukemia by Verbeek, Martijn W C, van der Velden, Vincent H J

“…Detection of minimal residual disease (MRD) is a major independent prognostic marker in the clinical management of pediatric and adult B-cell precursor Acute…”
Get full text

Variants in the L12 linker domain of KRT10 are causal to atypical epidermolytic ichthyosis by Velden, J. J. A. J., Gisbergen, M. W., Kamps, M. A. F., Janssen, R., Diercks, G. F. H., Steijlen, P. M., Geel, M., Bolling, M. C.

“…Epidermolytic ichthyosis (EI) is a type of congenital ichthyosis, characterized by erythema and blistering at birth followed by hyperkeratosis. EI is caused by…”
Get full text

Paediatric focal intracranial suppurative infection: a UK single-centre retrospective cohort study by van der Velden, Fabian J S, Battersby, Alexandra, Pareja-Cebrian, Lucia, Ross, Nicholas, Ball, Stephen L, Emonts, Marieke

“…Paediatric focal intracranial suppurative infections are uncommon but cause significant mortality and morbidity. There are no uniform guidelines regarding…”
Get full text

Mutations in the CDSN gene cause peeling skin disease and hypotrichosis simplex of the scalp by Velden, Jaap J. A. J., Geel, Michel, Engelhart, Jans J., Jonkman, Marcel F., Steijlen, Peter M.

“…Peeling skin disease is a rare genodermatosis characterized by superficial exfoliation or peeling of the skin. Peeling skin disease is caused by biallelic…”
Get full text

Severe COVID-19 Is Characterised by Perturbations in Plasma Amines Correlated with Immune Response Markers, and Linked to Inflammation and Oxidative Stress by Karu, Naama, Kindt, Alida, van Gammeren, Adriaan J, Ermens, Anton A M, Harms, Amy C, Portengen, Lutzen, Vermeulen, Roel C H, Dik, Willem A, Langerak, Anton W, van der Velden, Vincent H J, Hankemeier, Thomas

“…The COVID-19 pandemic raised a need to characterise the biochemical response to SARS-CoV-2 infection and find biological markers to identify therapeutic…”
Get full text

Analysis of minimal residual disease by Ig TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data by VAN DER VELDEN, V. H. J, CAZZANIGA, G, CAYUELA, J. M, TRKA, J, ECKERT, C, FORONI, L, ZUR STADT, U, BELDJORD, K, RAFF, T, VAN DER SCHOOT, C. E, VAN DONGEN, J. J. M, SCHRAUDER, A, HANCOCK, J, BADER, P, PANZER-GRUMAYER, E. R, FLOHR, T, SUTTON, R, CAVE, H, MADSEN, H. O

“…Most modern treatment protocols for acute lymphoblastic leukaemia (ALL) include the analysis of minimal residual disease (MRD). To ensure comparable MRD…”
Get full text

Plasma Oxylipins and Their Precursors Are Strongly Associated with COVID-19 Severity and with Immune Response Markers by Karu, Naama, Kindt, Alida, Lamont, Lieke, van Gammeren, Adriaan J, Ermens, Anton A M, Harms, Amy C, Portengen, Lutzen, Vermeulen, Roel C H, Dik, Willem A, Langerak, Anton W, van der Velden, Vincent H J, Hankemeier, Thomas

“…COVID-19 is characterised by a dysregulated immune response, that involves signalling lipids acting as mediators of the inflammatory process along the innate…”
Get full text

Stereotactic Body radiotherapy and pedicLE screw fixatioN During one hospital visit for patients with symptomatic unstable spinal metastases: a randomized trial (BLEND RCT) using the Trials within Cohorts (TwiCs) design by Huele, E H, van der Velden, J M, Kasperts, N, Eppinga, W S C, Grutters, J P C, Suelmann, B B M, Weening, A A, Delawi, D, Teunissen, S C C M, Verkooijen, H M, Verlaan, J J, Gal, R

“…Spinal metastases can lead to unremitting pain and neurological deficits, which substantially impair daily functioning and quality of life. Patients with…”
Get full text

Association of Altered Plasma Lipidome with Disease Severity in COVID-19 Patients by Zhang, Zhengzheng, Karu, Naama, Kindt, Alida, Singh, Madhulika, Lamont, Lieke, van Gammeren, Adriaan J, Ermens, Anton A M, Harms, Amy C, Portengen, Lutzen, Vermeulen, Roel C H, Dik, Willem A, Langerak, Anton W, van der Velden, Vincent H J, Hankemeier, Thomas

“…The severity of COVID-19 is linked to an imbalanced immune response. The dysregulated metabolism of small molecules and bioactive lipids has also been…”
Get full text

Reduced PTLD-related mortality in patients experiencing EBV infection following allo-SCT after the introduction of a protocol incorporating pre-emptive rituximab by van der Velden, W J F M, Mori, T, Stevens, W B C, de Haan, A F J, Stelma, F F, Blijlevens, N M A, Donnelly, J P

“…The mortality associated with post-transplant lymphoproliferative disorder (PTLD) induced by EBV infection can be reduced by monitoring EBV by…”
Get full text

The systemic treatment of recurrent ovarian cancer revisited by Baert, T., Ferrero, A., Sehouli, J., O'Donnell, D.M., González-Martín, A., Joly, F., van der Velden, J., Blecharz, P., Tan, D.S.P., Querleu, D., Colombo, N., du Bois, A., Ledermann, J.A.

“…Treatment approaches for relapsed ovarian cancer have evolved over the past decade from a calendar-based decision tree to a patient-oriented biologically…”
Get full text

Using Team-Based Learning to Teach Pharmacology within the Medical Curriculum by Luitjes, Nora L D, van der Velden, Gisela J, Pandit, Rahul

“…The primary goal of pharmacology teaching is to prepare medical students to prescribe medications both safely and efficiently. At the Utrecht University…”
Get full text

Intestinal damage determines the inflammatory response and early complications in patients receiving conditioning for a stem cell transplantation by van der Velden, Walter J F M, Herbers, Alexandra H E, Feuth, Ton, Schaap, Nicolaas P M, Donnelly, J Peter, Blijlevens, Nicole M A

“…Stem cell transplantation (SCT) is still complicated by the occurrence of fever and inflammatory complications attributed to neutropenia and subsequent…”
Get full text

Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia by Schotte, D, Chau, J C K, Sylvester, G, Liu, G, Chen, C, van der Velden, V H J, Broekhuis, M J C, Peters, T C J M, Pieters, R, Boer, M L den

“…MicroRNAs (miRNAs) control the expression of protein-coding genes in normal hematopoietic cells and, consequently, aberrant expression may contribute to…”
Get full text

Clinical significance of flowcytometric minimal residual disease detection in pediatric acute myeloid leukemia patients treated according to the DCOG ANLL97 MRC AML12 protocol by van der Velden, V H J, van der Sluijs-Geling, A, Gibson, B E S, te Marvelde, J G, Hoogeveen, P G, Hop, W C J, Wheatley, K, Bierings, M B, Schuurhuis, G J, de Graaf, S S N, van Wering, E R, van Dongen, J J M

“…Analysis of minimal residual disease (MRD) in childhood acute myeloid leukemia (AML) may predict for clinical outcome. MRD levels were assessed by…”
Get full text

Targeted drug delivery by gemtuzumab ozogamicin: mechanism-based mathematical model for treatment strategy improvement and therapy individualization by Jager, Eva, van der Velden, Vincent H J, te Marvelde, Jeroen G, Walter, Roland B, Agur, Zvia, Vainstein, Vladimir

“…Gemtuzumab ozogamicin (GO) is a chemotherapy-conjugated anti-CD33 monoclonal antibody effective in some patients with acute myeloid leukemia (AML). The optimal…”
Get full text

Segregation of myoblast fusion and muscle-specific gene expression by distinct ligand-dependent inactivation of GSK-3β by Pansters, N. A. M, van der Velden, J. L. J, Kelders, M. C. J. M, Laeremans, H, Schols, A. M. W. J, Langen, R. C. J

“…Myogenic differentiation involves myoblast fusion and induction of muscle-specific gene expression, which are both stimulated by pharmacological (LiCl),…”
Get full text

Unraveling allostery within the angiotensin II type 1 receptor for Gα q and β-arrestin coupling by Cao, Yubo, van der Velden, Wijnand J C, Namkung, Yoon, Nivedha, Anita K, Cho, Aaron, Sedki, Dana, Holleran, Brian, Lee, Nicholas, Leduc, Richard, Muk, Sanychen, Le, Keith, Bhattacharya, Supriyo, Vaidehi, Nagarajan, Laporte, Stéphane A

“…G protein-coupled receptors engage both G proteins and β-arrestins, and their coupling can be biased by ligands and mutations. Here, to resolve structural…”
Get more information

Citrulline and albumin as biomarkers for gastrointestinal mucositis in recipients of hematopoietic SCT by van der Velden, W J F M, Herbers, A H E, Brüggemann, R J M, Feuth, T, Peter Donnelly, J, Blijlevens, N M A

“…Gastrointestinal (GI) mucositis is a common side effect of intense chemotherapy to prepare patients for hematopoietic SCT. Measuring intestinal damage…”
Get full text