Search Results - "van der Veen, Elly L"
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Clinical-grade N-(4-[18F]fluorobenzoyl)-interleukin-2 for PET imaging of activated T-cells in humans
Published in EJNMMI radiopharmacy and chemistry (17-07-2019)“…Background Molecular imaging of immune cells might be a potential tool for response prediction, treatment evaluation and patient selection in inflammatory…”
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Interleukin-2 PET imaging in patients with metastatic melanoma before and during immune checkpoint inhibitor therapy
Published in European journal of nuclear medicine and molecular imaging (01-12-2021)“…Purpose Immune checkpoint inhibitors can induce a T cell–mediated anti-tumor immune response in patients with melanoma. Visualizing T cell activity using…”
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3
PET/CT Imaging of 89Zr-N-sucDf-Pembrolizumab in Healthy Cynomolgus Monkeys
Published in Molecular imaging and biology (01-04-2021)“…Purpose Programmed cell death-1 receptor (PD-1) and its ligand (PD-L1) are the targets for immunotherapy in many cancer types. Although PD-1 blockade has…”
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4
89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer
Published in Nature medicine (01-12-2018)“…Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) blockade is effective in a subset of patients with several tumor types, but predicting patient benefit…”
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5
Development and Evaluation of Interleukin-2-Derived Radiotracers for PET Imaging of T Cells in Mice
Published in Journal of Nuclear Medicine (01-09-2020)“…Recently, -(4- F-fluorobenzoyl)-interleukin-2 ( F-FB-IL2) was introduced as a PET tracer for T cell imaging. However, production is complex and time-consuming…”
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Molecular imaging to enlighten cancer immunotherapies and underlying involved processes
Published in Cancer treatment reviews (01-11-2018)“…•Molecular imaging enables visualization of important components involved in immunotherapy.•Radiopharmaceuticals can target tumor cells, immune cells and…”
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89 Zr-pembrolizumab biodistribution is influenced by PD-1-mediated uptake in lymphoid organs
Published in Journal for immunotherapy of cancer (01-10-2020)“…To better predict response to immune checkpoint therapy and toxicity in healthy tissues, insight in the in vivo behavior of immune checkpoint targeting…”
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Molecular Imaging of PD-L1 Expression and Dynamics with the Adnectin-Based PET Tracer 18 F-BMS-986192
Published in Journal of Nuclear Medicine (01-12-2020)“…F-BMS-986192, an adnectin-based human programmed cell death ligand 1 (PD-L1) tracer, was developed to noninvasively determine whole-body PD-L1 expression by…”
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Abstract 4208: Development of 18F-IL2: a PET radiotracer for imaging activated T-cells
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Introduction: Activation of T-cells is accompanied by a strong up-regulation of interleukin-2 (IL2) receptor (CD25). Therefore PET imaging of IL2…”
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89Zr-pembrolizumab biodistribution is influenced by PD-1-mediated uptake in lymphoid organs
Published in Journal for immunotherapy of cancer (01-10-2020)“…BackgroundTo better predict response to immune checkpoint therapy and toxicity in healthy tissues, insight in the in vivo behavior of immune checkpoint…”
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89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer
Published in Nature medicine (26-11-2018)Get full text
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sup.89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer
Published in Nature medicine (01-12-2018)“…Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) blockade is effective in a subset of patients with several tumor types, but predicting patient benefit…”
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Journal Article -
13
Molecular Imaging of PD-L1 Expression and Dynamics with the Adnectin-Based PET Tracer 18F-BMS-986192
Published in The Journal of nuclear medicine (1978) (01-12-2020)“…18F-BMS-986192, an adnectin-based human programmed cell death ligand 1 (PD-L1) tracer, was developed to noninvasively determine whole-body PD-L1 expression by…”
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Journal Article -
14
PET/CT Imaging of 89 Zr-N-sucDf-Pembrolizumab in Healthy Cynomolgus Monkeys
Published in Molecular imaging and biology (01-04-2021)“…Programmed cell death-1 receptor (PD-1) and its ligand (PD-L1) are the targets for immunotherapy in many cancer types. Although PD-1 blockade has therapeutic…”
Get full text
Journal Article -
15
89 Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer
Published in Nature medicine (01-12-2018)“…Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) blockade is effective in a subset of patients with several tumor types, but predicting patient benefit…”
Get full text
Journal Article