Search Results - "van der Staay, F.J"

Pharmacological and toxicological assessment of a potential GnRH vaccine in young-adult male pigs by Turkstra, J.A, van der Staay, F.J, Stockhofe-Zurwieden, N, Woelders, H, Meloen, R.H, Schuurman, T

“…Abstract Active immunization against gonadotrophin-releasing hormone (GnRH) is successfully applied to prevent boar taint in pork. In men, GnRH immunization…”
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Animal welfare: At the interface between science and society by Ohl, F., van der Staay, F.J.

“…The general concept of animal welfare embraces a continuum between negative/bad welfare and positive/good welfare. Early approaches to defining animal welfare…”
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Repeated social defeat in female pigs does not induce neuroendocrine symptoms of depression, but behavioral adaptation by van der Staay, F.J, de Groot, J, Schuurman, T, Korte, S.M

“…Abstract The aim of this study was to develop an animal model of major depression. Since two thirds of depressive patients are women, it is important to…”
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Testing post-weaning food motivation in low and normal birth weight pigs in a runway and operant conditioning task by van Eck, L.M., Antonides, A., Nordquist, R.E., van der Staay, F.J.

“…•We compared the motivation to obtain food rewards between low birth weight and normal birth weight pigs, using variable numbers of rewards in two separate…”
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No role for vitamin D or a moderate fat diet in aging induced cognitive decline and emotional reactivity in C57BL/6 mice by Brouwer-Brolsma, E.M., Schuurman, T., de Groot, L.C.P.M.G., Feskens, E.J.M., Lute, C., Naninck, E.F.G., Arndt, S.S., van der Staay, F.J., Bravenboer, N., Korosi, A., Steegenga, W.T.

“…•Aging significantly affects behavioral parameters related to emotion and cognition in mice.•Vitamin D deficiency or impaired glucose homeostasis did not…”
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Dissociable effects of acetylcholinesterase inhibitors and phosphodiesterase type 5 inhibitors on object recognition memory: acquisition versus consolidation by Prickaerts, L, Sik, A, Staay, F.J. van der, Vente, J. de, Blokland, A

“…Phosphodiesterase enzyme type 5 (PDE5) inhibitors and acetylcholinesterase (AChE) inhibitors have cognition-enhancing properties. However, it is not known…”
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Effects of two selective phosphodiesterase type 5 inhibitors, sildenafil and vardenafil, on object recognition memory and hippocampal cyclic GMP levels in the rat by Prickaerts, J, van Staveren, W.C.G, Şik, A, Markerink-van Ittersum, M, Niewöhner, U, van der Staay, F.J, Blokland, A, de Vente, J

“…The present study investigated the effects of two cyclic GMP-specific phosphodiesterase enzyme type 5 inhibitors, sildenafil and vardenafil, on the memory…”
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The d-amphetamine-treated Göttingen miniature pig: an animal model for assessing behavioral effects of antipsychotics by Staay, F.J. van der, Pouzet, B, Mahieu, M, Nordquist, R.E, Schuurman, T

“…Rationale Rodents are usually used to assess the ability of antipsychotic drugs to antagonize hyperlocomotion induced by dopamine agonists, such as the…”
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Emotional reactivity and cognitive performance in aversively motivated tasks: a comparison between four rat strains by Staay, F.J. van der, Schuurman, T, Reenen, C.G. van, Korte, S.M

“…Cognitive function might be affected by the subjects' emotional reactivity. We assessed whether behavior in different tests of emotional reactivity is…”
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Effects of surplus dietary L-tryptophan on stress, immunology, behavior, and nitrogen retention in endotoxemic pigs by Koopmans, S. J, van der Staay, F. J, Le Floc’h, N, Dekker, R, van Diepen, J. Th. M, Jansman, A. J. M

“…The possible beneficial effects of surplus dietary Trp (+5 g of Trp/kg of diet) on factors related to stress, immunology, behavior, and N retention were…”
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Recurrent long-lasting tethering reduces BDNF protein levels in the dorsal hippocampus and frontal cortex in pigs by De Vry, J., Prickaerts, J., Jetten, M., Hulst, M., Steinbusch, H.W.M., van den Hove, D.L.A., Schuurman, T., van der Staay, F.J.

“…Brain-derived neurotrophic factor (BDNF) signaling has been implicated in the onset of depression and in antidepressant efficacy, although the exact role of…”
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Spatial discrimination deficits by excitotoxic lesions in the Morris water escape task by Spowart-Manning, L., van der Staay, F.J.

“…The effects of the cholinesterase inhibitors (ChEI) metrifonate and donepezil were assessed on spatial performance of rats with bilateral lesions of the…”
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Effects of Butafosfan on salivary cortisol and behavioral response to social stress in piglets by VAN DER STAAY, F.J, DE GROOT, J, VAN REENEN, C.G, HOVING-BOLINK, A.H, SCHUURMAN, T, SCHMIDT, B.H

“…We assessed the efficacy of Butafosfan, a component of Catosal®, in the metaphylactic treatment of stress in pigs. Four 6-week-old female littermates were…”
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Absence of long-term behavioral effects after sub-chronic administration of low doses of methamidophos in male and female rats by Temerowski, M., van der Staay, F.J.

“…Putative long-term learning and memory effects of low-dose exposure to the cholinesterase inhibitor organophosphate methamidophos (Tamaron®) early in life were…”
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Object recognition testing: Rodent species, strains, housing conditions, and estrous cycle by van Goethem, Nick P., Rutten, Kris, van der Staay, Franz Josef, Jans, Linda A.W., Akkerman, Sven, Steinbusch, Harry W.M., Blokland, Arjan, van’t Klooster, José, Prickaerts, Jos

“…► This study investigated aspects in rodent object recognition testing related to generality and intervening variables. ► Object recognition appears to be a…”
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Effects of environmental enrichment on cognitive performance of pigs in a spatial holeboard discrimination task by Grimberg-Henrici, Charlotte G. E., Vermaak, Paul, Elizabeth Bolhuis, J., Nordquist, Rebecca E., van der Staay, F. Josef

“…This study investigated the effects of environmental enrichment on the cognitive performance of female conventional farm (growing) pigs in a spatial holeboard…”
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Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance by Boess, Frank G., Hendrix, Martin, van der Staay, Franz-Josef, Erb, Christina, Schreiber, Rudy, van Staveren, Wilma, de Vente, Jan, Prickaerts, Jos, Blokland, Arjan, Koenig, Gerhard

“…An essential element of the signalling cascade leading to synaptic plasticity is the intracellular second messenger molecule guanosine 3′,5′-cyclic…”
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Pathological anxiety in animals by Ohl, Frauke, Arndt, Saskia S., van der Staay, F. Josef

“…Selective breeding programmes in domestic and laboratory animals generally focus on physiological and/or anatomical characteristics. However, selection may…”
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Effects of maternal care and selection for low mortality on tyrosine hydroxylase concentrations and cell soma size in hippocampus and nidopallium caudolaterale in adult laying hen by Nordquist, R E, Zeinstra, E C, Rodenburg, T B, van der Staay, F J

“…Feather pecking and cannibalism in farm-kept laying hens are damaging behaviors both in terms of animal welfare and economic loss, and a major challenge in…”
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Two months make a difference in spatial orientation learning in very old hybrid Fischer 344 X Brown Norway (FBNF1) rats by Staay, F.J., van der

“…Age-related changes in cognitive performance may be more pronounced in the period near or exceeding the median life span. Therefore, we compared the…”
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