Search Results - "van der Spek, P. J."

The complement system in glioblastoma multiforme by Bouwens van der Vlis, T A M, Kros, J M, Mustafa, D A M, van Wijck, R T A, Ackermans, L, van Hagen, P M, van der Spek, P J

“…The human complement system is represents the main effector arm of innate immunity and its ambivalent function in cancer has been subject of ongoing dispute…”
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A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A by Ranish, Jeffrey A, Egly, Jean-Marc, Raams, Anja, van der Spek, P J, Aebersold, Ruedi, Hoeijmakers, Jan H J, Vermeulen, Wim, Jaspers, Nicolaas G J, Coin, Frederic, Theil, Arjan, Wijgers, Nils, Hoogstraten, Deborah, Argentini, Manuela, Stefanini, Miria, Giglia-Mari, Giuseppina, Botta, Elena

“…DNA repair-deficient trichothiodystrophy (TTD) results from mutations in the XPD and XPB subunits of the DNA repair and transcription factor TFIIH. In a third…”
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High-throughput microRNAome analysis in human germ cell tumours by Gillis, AJM, Stoop, HJ, Hersmus, R, Oosterhuis, JW, Sun, Y, Chen, C, Guenther, S, Sherlock, J, Veltman, I, Baeten, J, van der Spek, PJ, de Alarcon, P, Looijenga, LHJ

“…Testicular germ cell tumours (GCTs) of adolescents and adults can be subdivided into seminomas (referred to as dysgerminomas of the ovary) and non-seminomas,…”
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First-Trimester Crown-Rump Length and Embryonic Volume of Fetuses with Structural Congenital Abnormalities Measured in Virtual Reality: An Observational Study by Steegers, E. A. P., van der Spek, P. J., Koning, A. H. J., Benoit, B., Baken, L., Exalto, Niek

“…Background. With the introduction of three-dimensional (3D) ultrasound it has become possible to measure volumes. The relative increase in embryonic volume…”
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The maternal Mediterranean dietary pattern is associated with a reduced risk of spina bifida in the offspring by Vujkovic, M, Steegers, EA, Looman, CW, Ocké, MC, van der Spek, PJ, Steegers‐Theunissen, RP

“…Objective  The objective of this study was to test the hypothesis whether a maternal dietary pattern is associated with the risk of spina bifida (SB) in the…”
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First‐trimester crown–rump length and embryonic volume of aneuploid fetuses measured in virtual reality by Baken, L., van Heesch, P. N. A. C. M., Wildschut, H. I. J., Koning, A. H. J., van der Spek, P. J., Steegers, E. A. P., Exalto, N.

“…ABSTRACT Objectives To examine whether embryonic volume (EV), as measured using three‐dimensional (3D) ultrasound and a virtual reality approach, is a better…”
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Ustekinumab improves psoriasis-related gene expression in noninvolved psoriatic skin without inhibition of the antimicrobial response by Baerveldt, E.M., Onderdijk, A.J., Kurek, D., Kant, M., Florencia, E.F., Ijpma, A.S., van der Spek, P.J., Bastiaans, J., Jansen, P.A., van Kilsdonk, J.W.J., Laman, J.D., Prens, E.P.

“…Summary Background  Ustekinumab is a fully human anti‐p40 monoclonal antibody which neutralizes interleukin (IL)‐12 and IL‐23, thereby interfering with…”
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Associations between dietary patterns and semen quality in men undergoing IVF/ICSI treatment by Vujkovic, M., de Vries, J.H., Dohle, G.R., Bonsel, G.J., Lindemans, J., Macklon, N.S., van der Spek, P.J., Steegers, E.A.P., Steegers-Theunissen, R.P.M.

“…BACKGROUND This study investigates whether dietary patterns, substantiated by biomarkers, are associated with semen quality. METHODS In 161 men of subfertile…”
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An innovative virtual reality technique for automated human embryonic volume measurements by Rousian, M., Koning, A.H.J., van Oppenraaij, R.H.F., Hop, W.C., Verwoerd-Dikkeboom, C.M., van der Spek, P.J., Exalto, N., Steegers, E.A.P.

“…BACKGROUND The recent introduction of virtual reality (VR) enables us to use all three dimensions in a three-dimensional (3D) image. The aim of this…”
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First trimester brain ventricle fluid and embryonic volumes measured by three-dimensional ultrasound with the use of I-Space virtual reality by Rousian, M., Hop, W.C., Koning, A.H.J., van der Spek, P.J., Exalto, N., Steegers, E.A.P.

“…STUDY QUESTION Is it possible to evaluate first trimester brain ventricle development in human pregnancies using an innovative virtual reality (VR) application…”
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Reliability of three‐dimensional sonographic measurements in early pregnancy using virtual reality by Verwoerd‐Dikkeboom, C. M., Koning, A. H. J., Hop, W. C., Rousian, M., Van Der Spek, P. J., Exalto, N., Steegers, E. A. P.

“…Objective To establish the reliability of three‐dimensional (3D) ultrasound measurements in early pregnancy using a virtual reality system (the Barco I‐Space)…”
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The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7 by Hsu, S Y, Kudo, M, Chen, T, Nakabayashi, K, Bhalla, A, van der Spek, P J, van Duin, M, Hsueh, A J

“…Glycoprotein hormone receptors, including LH receptor, FSH receptor, and TSH receptor, belong to the large G protein-coupled receptor (GPCR) superfamily but…”
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Megalencephaly and perisylvian polymicrogyria with postaxial polydactyly and hydrocephalus (MPPH): report of a new case by Garavelli, L, Guareschi, E, Errico, S, Simoni, A, Bergonzini, P, Zollino, M, Gurrieri, F, Mancini, G M, Schot, R, Van Der Spek, P J, Frigieri, G, Zonari, P, Albertini, E, Giustina, E Della, Amarri, S, Banchini, G, Dobyns, W B, Neri, G

“…Megalencephaly (MEG), or enlargement of the brain, can either represent a familial variant with normal cerebral structure, or a rare brain malformation…”
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A virtual reality rendition of a fetal meningomyelocele at 32 weeks of gestation by Groenenberg, I. A. L., Koning, A. H. J., Galjaard, R. J., Steegers, E. A. P., Brezinka, C., van der Spek, P. J.

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Early pregnancy volume measurements: validation of ultrasound techniques and new perspectives by Rousian, M, Verwoerd‐Dikkeboom, CM, Koning, AHJ, Hop, WC, van der Spek, PJ, Exalto, N, Steegers, EAP

“…Objective  To investigate accuracy and reliability of four different ultrasound‐related volume‐measuring methods. Design  Observational study. Setting  Both in…”
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Gestational sac fluid volume measurements in virtual reality by Rousian, M., Koning, A. H. J., Hop, W. C., van der Spek, P. J., Exalto, N., Steegers, E. A. P.

“…Objectives To evaluate a virtual reality (VR) application for gestational sac fluid volume (GSFV) measurements in first‐trimester pregnancies and to study the…”
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Innovative virtual reality measurements for embryonic growth and development by Verwoerd-Dikkeboom, C.M., Koning, A.H.J., Hop, W.C., van der Spek, P.J., Exalto, N., Steegers, E.A.P.

“…BACKGROUND Innovative imaging techniques, using up-to-date ultrasonic equipment, necessitate specific biometry. The aim of our study was to test the…”
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Agreement and reliability of pelvic floor measurements during contraction using three‐dimensional pelvic floor ultrasound and virtual reality by Speksnijder, L., Rousian, M., Steegers, E. A. P., Van Der Spek, P. J., Koning, A. H. J., Steensma, A. B.

“…Objectives Virtual reality is a novel method of visualizing ultrasound data with the perception of depth and offers possibilities for measuring non‐planar…”
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The effect of smoking on early chorionic villous vascularisation by van Oppenraaij, R.H.F, Koning, A.H.J, van den Hoff, M.J.B, van der Spek, P.J, Steegers, E.A.P, Exalto, N

“…Abstract The aim of the study was to investigate whether first trimester chorionic villous vascularisation is different in women who smoked cigarettes before…”
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Human embryonic growth and development of the cerebellum using 3-dimensional ultrasound and virtual reality by Rousian, M, Groenenberg, I A L, Hop, W C, Koning, A H J, van der Spek, P J, Exalto, N, Steegers, E A P

“…The aim of our study was to evaluate the first trimester cerebellar growth and development using 2 different measuring techniques: 3-dimensional (3D) and…”
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