Search Results - "van der Reijden, Bert"

Successful Transfer of Umbilical Cord Blood CD34 + Hematopoietic Stem and Progenitor-derived NK Cells in Older Acute Myeloid Leukemia Patients by Dolstra, Harry, Roeven, Mieke W H, Spanholtz, Jan, Hangalapura, Basav N, Tordoir, Marleen, Maas, Frans, Leenders, Marij, Bohme, Fenna, Kok, Nina, Trilsbeek, Carel, Paardekooper, Jos, van der Waart, Anniek B, Westerweel, Peter E, Snijders, Tjeerd J F, Cornelissen, Jan, Bos, Gerard, Pruijt, Hans F M, de Graaf, Aniek O, van der Reijden, Bert A, Jansen, Joop H, van der Meer, Arnold, Huls, Gerwin, Cany, Jeannette, Preijers, Frank, Blijlevens, Nicole M A, Schaap, Nicolaas M

“…Older acute myeloid leukemia (AML) patients have a poor prognosis; therefore, novel therapies are needed. Allogeneic natural killer (NK) cells have been…”
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Transcription factor 4 ( TCF4 ) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia by In't Hout, Florentien E M, Gerritsen, Mylène, Bullinger, Lars, Van der Reijden, Bert A, Huls, Gerwin, Vellenga, Edo, Jansen, Joop H

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Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party by Schuurhuis, Gerrit J., Heuser, Michael, Freeman, Sylvie, Béné, Marie-Christine, Buccisano, Francesco, Cloos, Jacqueline, Grimwade, David, Haferlach, Torsten, Hills, Robert K., Hourigan, Christopher S., Jorgensen, Jeffrey L., Kern, Wolfgang, Lacombe, Francis, Maurillo, Luca, Preudhomme, Claude, van der Reijden, Bert A., Thiede, Christian, Venditti, Adriano, Vyas, Paresh, Wood, Brent L., Walter, Roland B., Döhner, Konstanze, Roboz, Gail J., Ossenkoppele, Gert J.

“…Measurable residual disease (MRD; previously termed minimal residual disease) is an independent, postdiagnosis, prognostic indicator in acute myeloid leukemia…”
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Sex Differences in the Spectrum of Clonal Hematopoiesis by Kamphuis, Priscilla, Zeventer, Isabelle A., Graaf, Aniek O., Salzbrunn, Jonas B., Bergen, Maaike G. J. M., Dinmohamed, Avinash G., Reijden, Bert A., Schuringa, Jan Jacob, Jansen, Joop H., Huls, Gerwin

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BCR::ABL1 kinase domain mutation testing and clinical outcome in a nationwide chronic myeloid leukemia patient population by Kockerols, Camille, Valk, Peter J. M., Blijlevens, Nicole M. A., Cornelissen, Jan J., Dinmohamed, Avinash G., Geelen, Inge, Hoogendoorn, Mels, Janssen, Jeroen J. W. M., Daenen, Laura G. M., Reijden, Bert A. van der, Westerweel, Peter E.

“…ObjectivesAcquired missense mutations in the BCR::ABL1 kinase domain (KD) may cause tyrosine kinase inhibitor (TKI) treatment failure. Based on…”
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Inducible MLL-AF9 Expression Drives an AML Program during Human Pluripotent Stem Cell-Derived Hematopoietic Differentiation by Heuts, Branco M H, Arza-Apalategi, Saioa, Alkema, Sinne G, Tijchon, Esther, Jussen, Laura, Bergevoet, Saskia M, van der Reijden, Bert A, Martens, Joost H A

“…A t(9;11)(p22;q23) translocation produces the MLL-AF9 fusion protein, which is found in up to 25% of de novo AML cases in children. Despite major advances,…”
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Mutations in epigenetic regulators in myelodysplastic syndromes by Nikoloski, Gorica, van der Reijden, Bert A., Jansen, Joop H.

“…Until recently, the genetic aberrations that are causally linked to the pathogenesis of myelodysplastic syndromes (MDS) and myeloproliferative neoplasms were…”
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The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice by Khandanpour, Cyrus, Krongold, Joseph, Schɒtte, Judith, Bouwman, Frederique, Vassen, Lothar, Gaudreau, Marie-Claude, Chen, Riyan, Calero-Nieto, Fernando J., Diamanti, Evangelia, Hannah, Rebecca, Meyer, Sara E., Grimes, H. Leighton, van der Reijden, Bert A., Jansen, Joop H., Patel, Chandrashekhar V., Peeters, Justine K., Löwenberg, Bob, Dɒhrsen, Ulrich, Göttgens, Bertie, Möröy, Tarik

“…The coding single nucleotide polymorphism GFI136N in the human gene growth factor independence 1 (GFI1) is present in 37-77 of whites and increases the risk…”
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The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension by Smit, Judith J, Monteferrario, Davide, Noordermeer, Sylvie M, van Dijk, Willem J, van der Reijden, Bert A, Sixma, Titia K

“…Activation of the NF‐κB pathway requires the formation of Met1‐linked ‘linear’ ubiquitin chains on NEMO, which is catalysed by the Linear Ubiquitin Chain…”
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Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals by van Zeventer, Isabelle A., de Graaf, Aniek O., Wouters, Hanneke J.C.M., van der Reijden, Bert A., van der Klauw, Melanie M., de Witte, Theo, Jonker, Marianne A., Malcovati, Luca, Jansen, Joop H., Huls, Gerwin

“…Anemia is a major and currently poorly understood clinical manifestation of hematopoietic aging. Upon aging, hematopoietic clones harboring acquired…”
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A Dominant-Negative GFI1B Mutation in the Gray Platelet Syndrome by Monteferrario, Davide, Bolar, Nikhita A, Marneth, Anna E, Hebeda, Konnie M, Bergevoet, Saskia M, Veenstra, Hans, Laros-van Gorkom, Britta A.P, MacKenzie, Marius A, Khandanpour, Cyrus, Botezatu, Lacramiora, Fransen, Erik, Van Camp, Guy, Duijnhouwer, Anthonie L, Salemink, Simone, Willemsen, Brigith, Huls, Gerwin, Preijers, Frank, Van Heerde, Waander, Jansen, Joop H, Kempers, Marlies J.E, Loeys, Bart L, Van Laer, Lut, Van der Reijden, Bert A

“…A large family is described with gray platelet syndrome due to an autosomal dominant inheritance pattern related to a dominant-negative mutation in GFI1B . The…”
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Clonal evolution in myelodysplastic syndromes by da Silva-Coelho, Pedro, Kroeze, Leonie I., Yoshida, Kenichi, Koorenhof-Scheele, Theresia N., Knops, Ruth, van de Locht, Louis T., de Graaf, Aniek O., Massop, Marion, Sandmann, Sarah, Dugas, Martin, Stevens-Kroef, Marian J., Cermak, Jaroslav, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, de Witte, Theo, Blijlevens, Nicole M. A., Muus, Petra, Huls, Gerwin, van der Reijden, Bert A., Ogawa, Seishi, Jansen, Joop H.

“…Cancer development is a dynamic process during which the successive accumulation of mutations results in cells with increasingly malignant characteristics…”
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Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes by Jansen, Joop H, Nikoloski, Gorica, Langemeijer, Saskia M C, Kuiper, Roland P, Knops, Ruth, Massop, Marion, Tönnissen, Evelyn R L T M, van der Heijden, Adrian, Scheele, Theresia N, Vandenberghe, Peter, de Witte, Theo, van der Reijden, Bert A

“…In myelodysplastic syndromes (MDS), deletions of chromosome 7 or 7q are common and correlate with a poor prognosis. The relevant genes on chromosome 7 are…”
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Acquired mutations in TET2 are common in myelodysplastic syndromes by Jansen, Joop H, Langemeijer, Saskia M C, Kuiper, Roland P, Berends, Marieke, Knops, Ruth, Aslanyan, Mariam G, Massop, Marion, Stevens-Linders, Ellen, van Hoogen, Patricia, van Kessel, Ad Geurts, Raymakers, Reinier A P, Kamping, Eveline J, Verhoef, Gregor E, Verburgh, Estelle, Hagemeijer, Anne, Vandenberghe, Peter, de Witte, Theo, van der Reijden, Bert A

“…Myelodysplastic syndromes (MDS) represent a heterogeneous group of neoplastic hematopoietic disorders. Several recurrent chromosomal aberrations have been…”
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Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia by Vassen, Lothar, Khandanpour, Cyrus, Ebeling, Peter, van der Reijden, Bert A., Jansen, Joop H., Mahlmann, Stefan, Dührsen, Ulrich, Möröy, Tarik

“…Gfi1b is a transcriptional repressor that is essential for erythroid cells and megakaryocytes, but is also expressed in hematopoietic stem cells and early…”
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Introducing high-throughput sequencing into mainstream genetic diagnosis practice in inherited platelet disorders by Bastida, José M, Lozano, María L, Benito, Rocío, Janusz, Kamila, Palma-Barqueros, Verónica, Del Rey, Mónica, Hernández-Sánchez, Jesús M, Riesco, Susana, Bermejo, Nuria, González-García, Hermenegildo, Rodriguez-Alén, Agustín, Aguilar, Carlos, Sevivas, Teresa, López-Fernández, María F, Marneth, Anna E, van der Reijden, Bert A, Morgan, Neil V, Watson, Steve P, Vicente, Vicente, Hernández-Rivas, Jesús M, Rivera, José, González-Porras, José R

“…Inherited platelet disorders are a heterogeneous group of rare diseases, caused by inherited defects in platelet production and/or function. Their genetic…”
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Real-Time Quantitative Polymerase Chain Reaction Detection of Minimal Residual Disease by Standardized WT1 Assay to Enhance Risk Stratification in Acute Myeloid Leukemia: A European LeukemiaNet Study by CILLONI, Daniela, RENNEVILLE, Aline, IZZO, Barbara, NOMDEDEU, Josep, VAN DER HEIJDEN, Adrian, VAN DER REIJDEN, BertA, JANSEN, Joop H, VAN DER VELDEN, Vincent H. J, OMMEN, Hans, PREUDHOMME, Claude, SAGLIO, Giuseppe, GRIMWADE, David, HERMITTE, Fabienne, HILLS, Robert K, DALY, Sarah, JOVANOVIC, Jelena V, GOTTARDI, Enrico, FAVA, Milena, SCHNITTGER, Susanne, WEISS, Tamara

“…Risk stratification in acute myeloid leukemia (AML) is currently based on pretreatment characteristics. It remains to be established whether relapse risk can…”
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Human mitochondrial ATP-binding cassette transporter ABCB10 is required for efficient red blood cell development by Tang, Leilei, Bergevoet, Saskia M., Bakker-Verweij, Greet, Harteveld, Cornelis L., Giordano, Piero C., Nijtmans, Leo, de Witte, Theo, Jansen, Joop H., Raymakers, Reinier A. P., van der Reijden, Bert A.

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Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCT by Berger, Gerbrig, Kroeze, Leonie I., Koorenhof-Scheele, Theresia N., de Graaf, Aniek O., Yoshida, Kenichi, Ueno, Hiroo, Shiraishi, Yuichi, Miyano, Satoru, van den Berg, Eva, Schepers, Hein, van der Reijden, Bert A., Ogawa, Seishi, Vellenga, Edo, Jansen, Joop H.

“…Therapy-related myeloid neoplasms (tMNs) are severe adverse events that can occur after treatment with autologous hematopoietic stem cell transplantation…”
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Clonal hematopoiesis and myeloid skewing in older population‐based individuals by Bergen, Maaike G. J. M., Kamphuis, Priscilla, Graaf, Aniek O., Salzbrunn, Jonas B., Koorenhof‐Scheele, Theresia N., Zeventer, Isabelle A., Dinmohamed, Avinash G., Schuringa, Jan Jacob, Reijden, Bert A., Huls, Gerwin, Jansen, Joop H.

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