Search Results - "van der Meulen, P."
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1
Controlling forward and backward rotary molecular motion on demand
Published in Nature communications (19-04-2022)“…Synthetic molecular machines hold tremendous potential to revolutionize chemical and materials sciences. Their autonomous motion controlled by external stimuli…”
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2
Terbium-161 for PSMA-targeted radionuclide therapy of prostate cancer
Published in European journal of nuclear medicine and molecular imaging (01-08-2019)“…Purpose The prostate-specific membrane antigen (PSMA) has emerged as an interesting target for radionuclide therapy of metastasized castration-resistant…”
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3
New Radionuclides and Technological Advances in SPECT and PET Scanners
Published in Cancers (08-12-2021)“…Developments throughout the history of nuclear medicine have involved improvements in both instrumentation and radionuclides, which have been intertwined…”
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4
Radiometals for imaging and theranostics, current production, and future perspectives
Published in Journal of labelled compounds & radiopharmaceuticals (01-08-2019)“…The aim of this review is to make the reader familiar with currently available radiometals, their production modes, capacities, and quality concerns related to…”
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5
Chelation of Theranostic Copper Radioisotopes with S-Rich Macrocycles: From Radiolabelling of Copper-64 to In Vivo Investigation
Published in Molecules (Basel, Switzerland) (28-06-2022)“…Copper radioisotopes are generally employed for cancer imaging and therapy when firmly coordinated via a chelating agent coupled to a tumor-seeking vector…”
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6
Activity Measurement of 44Sc and Calibration of Activity Measurement Instruments on Production Sites and Clinics
Published in Molecules (Basel, Switzerland) (31-01-2023)“…44Sc is a promising radionuclide for positron emission tomography (PET) in nuclear medicine. As a part of the implementation of a production site for 44Sc,…”
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7
Terbium-149 production: a focus on yield and quality improvement towards preclinical application
Published in Scientific reports (08-02-2024)“…Terbium-149 (T 1/2 = 4.1 h, E α = 3.98 MeV (16.7%), 28 µm range in tissue) is a radionuclide with potential for targeted alpha therapy. Due to the negligible…”
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8
A multi-technique approach to understanding delithiation damage in LiCoO2 thin films
Published in Scientific reports (08-06-2021)“…We report on the delithiation of LiCoO 2 thin films using oxalic acid (C 2 H 2 O 4 ) with the goal of understanding the structural degradation of an insertion…”
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9
Synthesis and Preclinical Evaluation of Radiolabeled [103Ru]BOLD-100
Published in Pharmaceutics (01-11-2023)“…The first-in-class ruthenium-based chemotherapeutic agent BOLD-100 (formerly IT-139, NKP-1339, KP1339) is currently the subject of clinical evaluation for the…”
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10
Developments toward the Implementation of 44Sc Production at a Medical Cyclotron
Published in Molecules (Basel, Switzerland) (14-10-2020)“…44Sc has favorable properties for cancer diagnosis using Positron Emission Tomography (PET) making it a promising candidate for application in nuclear…”
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11
Combination of Proton Therapy and Radionuclide Therapy in Mice: Preclinical Pilot Study at the Paul Scherrer Institute
Published in Pharmaceutics (02-09-2019)“…Proton therapy (PT) is a treatment with high dose conformality that delivers a highly-focused radiation dose to solid tumors. Targeted radionuclide therapy…”
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12
A Step-by-Step Guide for the Novel Radiometal Production for Medical Applications: Case Studies with 68Ga, 44Sc, 177Lu and 161Tb
Published in Molecules (Basel, Switzerland) (20-02-2020)“…The production of novel radionuclides is the first step towards the development of new effective radiopharmaceuticals, and the quality thereof directly affects…”
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13
Blue-to-green single photons from InGaN/GaN dot-in-a-nanowire ordered arrays
Published in Europhysics letters (01-07-2015)“…Single-photon emitters (SPEs) are at the basis of many applications for quantum information management. Semiconductor-based SPEs are best suited for practical…”
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14
Fifty Shades of Scandium: Comparative Study of PET Capabilities Using Sc-43 and Sc-44 with Respect to Conventional Clinical Radionuclides
Published in Diagnostics (Basel) (03-10-2021)“…Scandium-44 has been proposed as a valuable radionuclide for Positron Emission Tomography (PET). Recently, scandium-43 was introduced as a more favorable…”
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15
Cyclotron production and radiochemical purification of terbium-155 for SPECT imaging
Published in EJNMMI radiopharmacy and chemistry (14-11-2021)“…Background Terbium-155 [T 1/2 = 5.32 d, Eγ = 87 keV (32%) 105 keV (25%)] is an interesting radionuclide suitable for single photon emission computed…”
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16
A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides
Published in EJNMMI research (19-04-2023)“…Purpose The angiotensin converting enzyme-2 (ACE2)—entry receptor of SARS-CoV-2—and its homologue, the angiotensin-converting enzyme (ACE), play a pivotal role…”
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Simultaneous Visualization of 161Tb- and 177Lu-Labeled Somatostatin Analogues Using Dual-Isotope SPECT Imaging
Published in Pharmaceutics (12-04-2021)“…The decay of terbium-161 results in the emission of β¯-particles as well as conversion and Auger electrons, which makes terbium-161 interesting for therapeutic…”
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18
Establishment of a clinical SPECT/CT protocol for imaging of 161Tb
Published in EJNMMI physics (01-07-2020)“…Background It has been proposed, and preclinically demonstrated, that 161 Tb is a better alternative to 177 Lu for the treatment of small prostate cancer…”
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19
Precise activity measurements of medical radionuclides using an ionization chamber: a case study with Terbium-161
Published in EJNMMI physics (14-03-2022)“…Background 161 Tb draws an increasing interest in nuclear medicine for therapeutic applications. More than 99% of the emitted gamma and X-rays of 161 Tb have…”
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20
Experimental verification of the chemical sensitivity of two-site double core-hole states formed by an x-ray free-electron laser
Published in Physical review letters (13-04-2012)“…We have performed x-ray two-photon photoelectron spectroscopy using the Linac Coherent Light Source x-ray free-electron laser in order to study double…”
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