Search Results - "van der Linden, Paul D."
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Current evidence on hospital antimicrobial stewardship objectives: a systematic review and meta-analysis
Published in The Lancet infectious diseases (01-07-2016)“…Summary Background Antimicrobial stewardship is advocated to improve the quality of antimicrobial use. We did a systematic review and meta-analysis to assess…”
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Women on diuretics have a higher risk of hospital admission because of hyponatremia than men
Published in Pharmacoepidemiology and drug safety (01-06-2023)“…Purpose Recent studies suggest that women are more susceptible to diuretic‐induced hyponatremia resulting in hospital admission than men. The aim of this study…”
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Confounding by indication of the safety of de-escalation in community-acquired pneumonia: A simulation study embedded in a prospective cohort
Published in PloS one (27-09-2019)“…Observational studies have demonstrated that de-escalation of antimicrobial therapy is independently associated with lower mortality. This most probably…”
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Performance of ChatGPT on Factual Knowledge Questions Regarding Clinical Pharmacy
Published in Journal of clinical pharmacology (01-09-2024)“…ChatGPT is a language model that was trained on a large dataset including medical literature. Several studies have described the performance of ChatGPT on…”
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Sepsis calculator implementation reduces empiric antibiotics for suspected early-onset sepsis
Published in European journal of pediatrics (01-05-2018)“…Significant overtreatment with antibiotics for suspected early onset sepsis (EOS) constitutes a persisting clinical problem, generating unnecessary risks,…”
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Ciprofloxacin Pharmacokinetics After Oral and Intravenous Administration in (Morbidly) Obese and Non-obese Individuals: A Prospective Clinical Study
Published in Clinical pharmacokinetics (01-08-2022)“…Background and Objective Ciprofloxacin is a fluoroquinolone used for empirical and targeted therapy of a wide range of infections. Despite the increase in…”
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Narrow-spectrum antibiotics for community-acquired pneumonia in Dutch adults (CAP-PACT): a cross-sectional, stepped-wedge, cluster-randomised, non-inferiority, antimicrobial stewardship intervention trial
Published in The Lancet infectious diseases (01-02-2022)“…Adults hospitalised to a non-intensive care unit (ICU) ward with moderately severe community-acquired pneumonia are frequently treated with broad-spectrum…”
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Pooled Population Pharmacokinetic Analysis and Dose Recommendations for Ciprofloxacin in Intensive Care Unit Patients with Obesity
Published in Journal of clinical pharmacology (01-09-2024)“…Recent studies have explored the influence of obesity and critical illness on ciprofloxacin pharmacokinetics. However, variation across the subpopulation of…”
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Diabetes and Glucose Dysregulation and Transition to Delirium in ICU Patients
Published in Critical care medicine (01-09-2018)“…OBJECTIVES:To investigate whether diabetes and glucose dysregulation (hyperglycemia and/or hypoglycemia) are associated with ICU delirium. DESIGN:Prospective…”
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Assessment of drug-related problems at the emergency department in older patients living with frailty: pharmacist-led medication reviews within a geriatric care team
Published in BMC geriatrics (05-04-2023)“…Older patients are vulnerable to experiencing drug related problems (DRPs), which may result in emergency department (ED) visits. However, it is not standard…”
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Women are started on a lower daily dose of metoprolol than men irrespective of dose recommendations: A potential source of confounding by contraindication in pharmacoepidemiology
Published in Pharmacoepidemiology and drug safety (01-07-2021)“…Purpose Current guidelines have no sex‐specific dosage advice for metoprolol. To evaluate whether women and men are prescribed the same dose a cohort analysis…”
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Glucose variability during delirium in diabetic and non-diabetic intensive care unit patients: A prospective cohort study
Published in PloS one (15-11-2018)“…To determine whether glucose variability is altered during delirium days compared to non-delirious days in critically ill patients with and without diabetes in…”
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The 2021 Dutch Working Party on Antibiotic Policy (SWAB) guidelines for empirical antibacterial therapy of sepsis in adults
Published in BMC infectious diseases (11-08-2022)“…Abstract Background The Dutch Working Party on Antibiotic Policy (SWAB) in collaboration with relevant professional societies, has updated their evidence-based…”
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Assessing accuracy of ChatGPT in response to questions from day to day pharmaceutical care in hospitals
Published in Exploratory research in clinical and social pharmacy (01-09-2024)“…The advent of Large Language Models (LLMs) such as ChatGPT introduces opportunities within the medical field. Nonetheless, use of LLM poses a risk when…”
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Severe epistaxis related to intravitreal bevacizumab
Published in Acta ophthalmologica (Oxford, England) (01-02-2020)Get full text
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Consecutive antibiotic use in the outpatient setting: an extensive, longitudinal descriptive analysis of antibiotic dispensing data in the Netherlands
Published in BMC infectious diseases (24-01-2019)“…Taking consecutive antibiotic use into account is of importance to obtain insight in treatment within disease episodes, use of 2nd- and 3rd-choice antibiotics,…”
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Risk of Hospitalization for Hypoglycemia in Older Patients with Diabetes Using Antipsychotic Drugs
Published in The American journal of geriatric psychiatry (01-11-2015)“…Objective Antipsychotics may disrupt metabolic regulation in patients with diabetes mellitus. The risk of hypoglycemia in older users of antipsychotics with…”
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Antibiotic prescribing on admission to patients with pneumonia and prior outpatient antibiotic treatment: a cohort study on clinical outcome
Published in BMJ open (12-02-2015)“…Objective Most pneumonia treatment guidelines recommend that prior outpatient antibiotic treatment should be considered when planning inpatient antibiotic…”
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Diagnosis-linked antibiotic prescribing quality indicators: demonstrating feasibility using practice-based routine primary care data, reliability, validity and their potential in antimicrobial stewardship
Published in Journal of antimicrobial chemotherapy (02-04-2024)“…Quality indicators (QIs) can be used to obtain valuable insights into prescribing quality. Five quantitative and nine diagnosis-linked QIs, aiming to provide…”
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Poor performance of ChatGPT in clinical rule-guided dose interventions in hospitalized patients with renal dysfunction
Published in European journal of clinical pharmacology (01-08-2024)“…Purpose Clinical decision support systems (CDSS) are used to identify drugs with potential need for dose modification in patients with renal impairment…”
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