Search Results - "van der Linden, Michael P M"

Baseline serum adipokine levels predict radiographic progression in early rheumatoid arthritis by Klein‐Wieringa, Inge R., van der Linden, Michael P. M., Knevel, Rachel, Kwekkeboom, Joanneke C., van Beelen, Els, Huizinga, Tom W. J., van der Helm‐van Mil, Annette, Kloppenburg, Margreet, Toes, René E. M., Ioan‐Facsinay, Andreea

“…Objective Adipose tissue can secrete soluble mediators (adipokines) with potent immune regulatory functions. Some adipokines have been previously associated…”
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Long‐term impact of delay in assessment of patients with early arthritis by van der Linden, Michael P. M., le Cessie, Saskia, Raza, Karim, van der Woude, Diane, Knevel, Rachel, Huizinga, Tom W. J., van der Helm‐van Mil, Annette H. M.

“…Objective During the last decade, rheumatologists have learned to initiate disease‐modifying antirheumatic drugs (DMARDs) early to improve the outcome of…”
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Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis by Scherer, Hans Ulrich, van der Woude, Diane, Willemze, Annemiek, Trouw, Leendert A, Knevel, Rachel, Syversen, Silje W, van der Linden, Michael P M, Lie, Benedicte, Huizinga, Tom W J, van der Heijde, Désirée M F M, van der Helm-van Mil, Annette H M, Kvien, Tore K, Toes, René E M

“…Human leucocyte antigen shared epitope (SE) alleles are associated with joint destruction, the presence of anticitrullinated protein antibodies (ACPA) and the…”
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The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis by van der Woude, Diane, Syversen, Silje W, van der Voort, Ellen I H, Verpoort, Kirsten N, Goll, Guro L, van der Linden, Michael P M, van der Helm-van Mil, Annette H M, van der Heijde, Désirée M F M, Huizinga, Tom W J, Kvien, Tore K, Toes, René E M

“…The presence of anti-citrullinated protein antibodies (ACPA) is a powerful predictive factor for the development and progression of rheumatoid arthritis (RA)…”
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Repair of joint erosions in rheumatoid arthritis: prevalence and patient characteristics in a large inception cohort by van der Linden, Michael P M, Boja, Ramona, Klarenbeek, Naomi B, Huizinga, Tom W J, van der Heijde, Désirée M, van der Helm-van Mil, Annette H M

“…Joint destruction in rheumatoid arthritis (RA) was until recently seen as an irreversible state. Lately, it was found that repair of bone erosions occurs;…”
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Association of the 6q23 region with the rate of joint destruction in rheumatoid arthritis by Scherer, Hans Ulrich, van der Linden, Michael P M, Kurreeman, Fina A S, Stoeken-Rijsbergen, Gerrie, Cessie, Saskia le, Huizinga, Tom W J, van der Helm-van Mil, Annette H, Toes, René E M

“…Two novel genetic polymorphisms on chromosome 6q23 are associated with susceptibility to rheumatoid arthritis (RA). Both polymorphisms (rs6920220 and…”
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The window of opportunity in ACPA-positive rheumatoid arthritis is not explained by ACPA characteristics by Willemze, Annemiek, van der Linden, Michael P M, le Cessie, Saskia, Trouw, Leendert A, Toes, Rene E M, Huizinga, Tom W J, van der Helm-van Mil, Annette H M

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Predicting arthritis outcomes--what can be learned from the Leiden Early Arthritis Clinic? by de Rooy, Diederik P C, van der Linden, Michael P M, Knevel, Rachel, Huizinga, Tom W J, van der Helm-van Mil, Annette H M

“…In order to allow personalized medicine, adequate prediction of disease outcome is required. In early undifferentiated arthritis (UA), prediction of the…”
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Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis by Knevel, Rachel, Klein, Kerstin, Somers, Klaartje, Ospelt, Caroline, Houwing-Duistermaat, Jeanine J, van Nies, Jessica A B, de Rooy, Diederik P C, de Bock, Laura, Kurreeman, Fina A S, Schonkeren, Joris, Stoeken-Rijsbergen, Gerrie, Helmer, Quinta, van der Linden, Michael P M, Kern, Marlena, Manjarrez-Orduno, Nataly, Rodriguez-Rodriquez, Luis, Stinissen, Piet, Huizinga, Tom W J, Toes, Rene E M, Gay, Steffen, Gregersen, Peter K, Somers, Veerle, van der Helm-van Mil, Annette H M

“…Joint destruction is a hallmark of autoantibody-positive rheumatoid arthritis (RA), though the severity is highly variable between patients. The processes…”
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Value of anti–modified citrullinated vimentin and third‐generation anti–cyclic citrullinated peptide compared with second‐generation anti–cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis and rheumatoid arthritis by van der Linden, Michael P. M., van der Woude, Diane, Ioan‐Facsinay, Andreea, Levarht, E. W. Nivine, Stoeken‐Rijsbergen, Gerrie, Huizinga, Tom W. J., Toes, René E. M., van der Helm‐van Mil, Annette H. M.

“…Objective Autoantibodies such as rheumatoid factor (RF) and anti–citrullinated protein autoantibodies (ACPAs) determined by testing with second‐generation…”
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Association of a single‐nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis by van der Linden, Michael P. M., Feitsma, Anouk L., le Cessie, Saskia, Kern, Marlena, Olsson, Lina M., Raychaudhuri, Soumya, Begovich, Ann B., Chang, Monica, Catanese, Joseph J., Kurreeman, Fina A. S., van Nies, Jessica, van der Heijde, Désirée M., Gregersen, Peter K., Huizinga, Tom W. J., Toes, René E. M., van der Helm‐Van Mil, Annette H. M.

“…Objective The severity of joint destruction in rheumatoid arthritis (RA) is highly variable from patient to patient and is influenced by genetic factors…”
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Predicting arthritis outcomes-what can be learned from the Leiden Early Arthritis Clinic?: Registries in Rheumatological and Musculoskeletal Conditions by DE ROOY, Diederik P. C, VAN DER LINDEN, Michael P. M, KNEVEL, Rachel, HUIZINGA, Tom W. J, VAN DER HELM-VAN MIL, Annette H. M

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