Search Results - "van der Leeuw, S."
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Sustainability, culture and personal responsibility
Published in Sustainability science (01-04-2014)Get full text
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Using real-world data to dynamically predict flares during tapering of biological DMARDs in rheumatoid arthritis: development, validation, and potential impact of prediction-aided decisions
Published in Arthritis research & therapy (23-03-2022)“…Biological disease-modifying antirheumatic drugs (bDMARDs) are effective in the treatment of rheumatoid arthritis. However, as bDMARDs may also lead to adverse…”
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Prediction Aided Tapering In rheumatoid arthritis patients treated with biOlogicals (PATIO): protocol for a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (16-06-2022)“…Background Biological disease-modifying anti-rheumatic drugs (bDMARDs) are effective in the treatment of rheumatoid arthritis (RA) but are expensive and…”
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Concomitant prednisone may alleviate methotrexate side-effects in rheumatoid arthritis patients
Published in BMC rheumatology (17-05-2023)“…To evaluate whether addition of low-moderate dose prednisone to methotrexate (MTX) treatment can alleviate common MTX side-effects in rheumatoid arthritis (RA)…”
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Effectiveness of TOcilizumab in comparison to Prednisone In Rheumatoid Arthritis patients with insufficient response to disease-modifying antirheumatic drugs (TOPIRA): study protocol for a pragmatic trial
Published in Current controlled trials in cardiovascular medicine (05-04-2020)“…Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease, predominantly affecting joints, which is initially treated with conventional synthetic…”
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Urbanization in and for the Anthropocene
Published in npj Urban Sustainability (23-02-2021)“…Key insights on needs in urban regional governance - Global urbanization (the increasing concentration in urban settlements of the increasing world…”
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WHY MODEL?
Published in Cybernetics and systems (01-03-2004)“…I discuss the utility of modeling in the social sciences, with emphasis on the long-term study of the coevolution between society and nature. I emphasize the…”
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Mapping the biosphere: exploring species to understand the origin, organization and sustainability of biodiversity
Published in Systematics and biodiversity (01-03-2012)“…The time is ripe for a comprehensive mission to explore and document Earth's species. This calls for a campaign to educate and inspire the next generation of…”
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262 (PB250): High-throughput fluorescence-based screening assay for indoleamine 2,3-dioxygenase 2 (IDO2)
Published in European journal of cancer (1990) (01-10-2024)Get full text
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Plausible and desirable futures in the Anthropocene: A new research agenda
Published in Global environmental change (01-07-2016)“…•The Anthropocene encapsulates a world of intertwined drivers, complex dynamic structures, emergent phenomena, and unintended consequences.•Much of the debate…”
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Antioxidant activity in raspberry, currant and gooseberry accessions of the Canadian clonal genebank
Published in Acta horticulturae (01-01-2007)Get full text
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Urban Transitions: On Urban Resilience and Human-Dominated Ecosystems
Published in Ambio (01-12-2010)“…Urbanization is a global multidimensional process paired with increasing uncertainty due to climate change, migration of people, and changes in the capacity to…”
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Resilience and Vulnerability: Complementary or Conflicting Concepts?
Published in Ecology and society (01-01-2010)“…Resilience and vulnerability represent two related yet different approaches to understanding the response of systems and actors to change; to shocks and…”
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The globalization of socio-ecological systems: An agenda for scientific research
Published in Global environmental change (01-08-2006)“…We argue that globalization is a central feature of coupled human–environment systems or, as we call them, socio-ecological systems (SESs). In this article, we…”
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Complex Land Systems: the Need for Long Time Perspectives to Assess their Future
Published in Ecology and society (2010)“…The growing awareness about the need to anticipate the future of land systems focuses on how well we understand the interactions between society and…”
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Toward an Integrated History to Guide the Future
Published in Ecology and society (01-01-2011)“…Many contemporary societal challenges manifest themselves in the domain of human–environment interactions. There is a growing recognition that responses to…”
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Placing Archaeology at the Center of Socio-Natural Studies
Published in American antiquity (01-10-2002)“…Changing patterns of university and government research and training in this country and abroad force us, as archaeologists, to regularly reevaluate our…”
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Planetary Boundaries: Exploring the Safe Operating Space for Humanity
Published in Ecology and society (01-12-2009)“…Anthropogenic pressures on the Earth System have reached a scale where abrupt global environmental change can no longer be excluded. We propose a new approach…”
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Resilience, vulnerability, and adaptation: a cross-cutting theme of the human dimensions of global environmental change program
Published in Global environmental change (01-08-2006)Get full text
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