Search Results - "van der Leest, Douwe"

Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS by van Belzen, Ianthe A E M, Cai, Casey, van Tuil, Marc, Badloe, Shashi, Strengman, Eric, Janse, Alex, Verwiel, Eugène T P, van der Leest, Douwe F M, Kester, Lennart, Molenaar, Jan J, Meijerink, Jules, Drost, Jarno, Peng, Weng Chuan, Kerstens, Hindrik H D, Tops, Bastiaan B J, Holstege, Frank C P, Kemmeren, Patrick, Hehir-Kwa, Jayne Y

“…Gene fusions are important cancer drivers in pediatric cancer and their accurate detection is essential for diagnosis and treatment. Clinical decision-making…”
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Molecular Characterization Reveals Subclasses of 1q Gain in Intermediate Risk Wilms Tumors by van Belzen, Ianthe A E M, van Tuil, Marc, Badloe, Shashi, Strengman, Eric, Janse, Alex, Verwiel, Eugène T P, van der Leest, Douwe F M, de Vos, Sam, Baker-Hernandez, John, Groenendijk, Alissa, de Krijger, Ronald, Kerstens, Hindrik H D, Drost, Jarno, van den Heuvel-Eibrink, Marry M, Tops, Bastiaan B J, Holstege, Frank C P, Kemmeren, Patrick, Hehir-Kwa, Jayne Y

“…Chromosomal alterations have recurrently been identified in Wilms tumors (WTs) and some are associated with poor prognosis. Gain of 1q (1q+) is of special…”
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Trecode: A FAIR Eco-System for the Analysis and Archiving of Omics Data in a Combined Diagnostic and Research Setting by Kerstens, Hindrik HD, Hehir-Kwa, Jayne Y, van de Geer, Ellen, van Run, Chris, Badloe, Shashi, Janse, Alex, Baker-Hernandez, John, de Vos, Sam, van der Leest, Douwe, Verwiel, Eugène TP, Tops, Bastiaan BJ, Kemmeren, Patrick

“…The increase in speed, reliability, and cost-effectiveness of high-throughput sequencing has led to the widespread clinical application of genome (WGS), exome…”
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RNA-Sequencing Improves Diagnostics and Treatment of Pediatric Hematological Malignancies by Koudijs, Marco J., Kester, Lennart A., Hehir-Kwa, Jayne Y., Verwiel, Eugene T.P., Strengman, Erik, van Tuil, Marc, van der Leest, Douwe, Sonneveld, Edwin, Kemmeren, Patrick, Haas, Valerie De, Vormoor, Josef, Tops, Bas B.J.

“…Abstract Background Diagnosis and treatment of hematological malignancies relies increasingly on the detection of underlying genetic abnormalities. Various…”
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