Search Results - "van der Korput, H A"

Characterization of the human androgen receptor transcription unit by FABER, P. W, VAN ROOIJ, H. C. J, VAN DER KORPUT, H. A. G. M, BAARENDS, W. M, BRINKMANN, A. O, GROOTEGOED, J. A, TRAPMAN, J

“…A full length human androgen receptor (hAR) cDNA was constructed from cDNA and genomic clones. Structurally the 10.6-kilobase (kb) hAR cDNA consists of a long…”
Get full text

Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species by Riegman, P H, Vlietstra, R J, van der Korput, H A, Romijn, J C, Trapman, J

“…The screening of an oligo(dT)-primed prostate cDNA library with a human glandular kallikrein-1 (hGK-1) genomic DNA fragment resulted in the isolation of two…”
Get more information

An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter by Cleutjens, K B, van der Korput, H A, van Eekelen, C C, van Rooij, H C, Faber, P W, Trapman, J

“…Prostate-specific antigen (PSA) is expressed at a high level in the luminal epithelial cells of the prostate and is absent or expressed at very low levels in…”
Get full text

Targeted biallelic inactivation of pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis by XIAOQIAN MA, ZIEL-VAN DER MADE, Angelique C, VAN DER KWAST, Theo H, TRAPMAN, Jan, AUTAR, Binha, VAN DER KORPUT, Hetty A, VERMEIJ, Marcel, VAN DUIJN, Petra, CLEUTJENS, Kitty B, DE KRIJGER, Ronald, KRIMPENFORT, Paul, BERNS, Anton

“…The PTEN tumor suppressor gene is frequently inactivated in human tumors, including prostate cancer. Based on the Cre/loxP system, we generated a novel mouse…”
Get full text

Two Androgen Response Regions Cooperate in Steroid Hormone Regulated Activity of the Prostate-specific Antigen Promoter by Cleutjens, K B, van Eekelen, C C, van der Korput, H A, Brinkmann, A O, Trapman, J

“…Transcription of the prostate-specific antigen (PSA) gene is androgen regulated. The PSA promoter contains at position −170 the sequence AGAACAgcaAGTGCT,…”
Get full text

Identification of Two Transcription Activation Units in the N-terminal Domain of the Human Androgen Receptor (∗) by Jenster, Guido, van der Korput, Hetty A.G.M., Trapman, Jan, Brinkmann, Albert O.

“…To locate in detail the regions in the human androgen receptor (AR) involved in transcription activation, a series of N-terminal deletions was introduced in…”
Get full text

A 6-kb promoter fragment mimics in transgenic mice the prostate-specific and androgen-regulated expression of the endogenous prostate-specific antigen gene in humans by Cleutjens, K B, van der Korput, H A, Ehren-van Eekelen, C C, Sikes, R A, Fasciana, C, Chung, L W, Trapman, J

“…Prostate-specific antigen (PSA) is a kallikrein-like serine protease, which is almost exclusively synthesized in the luminal epithelial cells of the human…”
Get full text

Characterization of monoclonal antibodies raised against the prostatic cancer cell line PC-82 by Gallee, M P, van Vroonhoven, C C, van der Korput, H A, van der Kwast, T H, ten Kate, F J, Romijn, J C, Trapman, J

“…For production of monoclonal antibodies (McAbs), hybrid cells were prepared by fusion of spleen cells of BALB/c mice immunized with the human prostatic cancer…”
Get more information

Domains of the human androgen receptor involved in steroid binding, transcriptional activation, and subcellular localization by Jenster, G, van der Korput, H A, van Vroonhoven, C, van der Kwast, T H, Trapman, J, Brinkmann, A O

“…A series of human androgen receptor (AR) deletion mutants was constructed to study the relationship between the structural domains and their different…”
Get more information

Changes in the Abundance of Androgen Receptor Isotypes: Effects of Ligand Treatment, Glutamine-Stretch Variation, and Mutation of Putative Phosphorylation Sites by Jenster, Guido, de Ruiter, Petra E, van der Korput, Hetty A. G. M, Kuiper, George G. J. M, Trapman, Jan, Brinkmann, Albert O

“…The SDS-polyacrylamide gel electrophoresis (SDS-PAGE) migration pattern of wild-type and mutated human androgen receptors (ARs) expressed in COS-1 cells was…”
Get full text

An Sp1 binding site is essential for basal activity of the human prostate-specific transglutaminase gene ( TGM4) promoter by Dubbink, Hendrikus J., Cleutjens, Kitty B.J.M., van der Korput, Hetty A.G.M., Trapman, Jan, Romijn, Johannes C.

“…Human prostate-specific transglutaminase (hTG P) is a cross-linking enzyme encoded by the TGM4 gene. The TGM4 gene promoter was characterized by deletion…”
Get full text

Dog MHC class I antigens contain beta 2-microglobulin by van der Feltz, M J, van der Korput, H A, Giphart, M J, Westbroek, D L

“…Detergent-solubilized DLA class I antigens have been isolated by immunoprecipitation from peripheral blood lymphocytes with an anti-beta 2-microglobulin serum…”
Get more information