Search Results - "van der Kooi, Elvera J."

Human IgE does not bind to human FcRn by Brinkhaus, Maximilian, van der Kooi, Elvera J., Bentlage, Arthur E. H., Ooijevaar-de Heer, Pleuni, Derksen, Ninotska I. L., Rispens, Theo, Vidarsson, Gestur

“…The neonatal Fc receptor (FcRn) is known to mediate placental transfer of IgG from mother to unborn. IgE is widely known for triggering immune responses to…”
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The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement by Brinkhaus, Maximilian, Pannecoucke, Erwin, van der Kooi, Elvera J., Bentlage, Arthur E. H., Derksen, Ninotska I. L., Andries, Julie, Balbino, Bianca, Sips, Magdalena, Ulrichts, Peter, Verheesen, Peter, de Haard, Hans, Rispens, Theo, Savvides, Savvas N., Vidarsson, Gestur

“…Binding to the neonatal Fc receptor (FcRn) extends serum half-life of IgG, and antagonizing this interaction is a promising therapeutic approach in…”
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Extracellular Vesicles: A New Source of Biomarkers in Pediatric Solid Tumors? A Systematic Review by Lak, Nathalie S M, van der Kooi, Elvera J, Enciso-Martinez, Agustin, Lozano-Andrés, Estefanía, Otto, Cees, Wauben, Marca H M, Tytgat, Godelieve A M

“…Virtually every cell in the body releases extracellular vesicles (EVs), the contents of which can provide a "fingerprint" of their cellular origin. EVs are…”
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IgG Fab Glycans Hinder FcRn-Mediated Placental Transport by Volkov, Mikhail, Brinkhaus, Maximilian, van Schie, Karin A, Bondt, Albert, Kissel, Theresa, van der Kooi, Elvera J, Bentlage, Arthur E H, Koeleman, Carolien A M, de Taeye, Steven W, Derksen, Ninotska I, Dolhain, Radboud J E M, Braig-Scherer, Ute, Huizinga, Tom W J, Wuhrer, Manfred, Toes, René E M, Vidarsson, Gestur, van der Woude, Diane

“…Abs can be glycosylated in both their Fc and Fab regions with marked effects on Ab function and binding. High levels of IgG Fab glycosylation are associated…”
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