Search Results - "van der Kolk, Birgitta W."

Metabolic profiling of tissue-specific insulin resistance in human obesity: results from the Diogenes study and the Maastricht Study by Vogelzangs, Nicole, van der Kallen, Carla J. H., van Greevenbroek, Marleen M. J., van der Kolk, Birgitta W., Jocken, Johan W. E., Goossens, Gijs H., Schaper, Nicolaas C., Henry, Ronald M. A., Eussen, Simone J. P. M., Valsesia, Armand, Hankemeier, Thomas, Astrup, Arne, Saris, Wim H. M., Stehouwer, Coen D. A., Blaak, Ellen E., Arts, Ilja C. W.

“…Background Recent evidence indicates that insulin resistance (IR) in obesity may develop independently in different organs, representing different etiologies…”
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Differential Mitochondrial Gene Expression in Adipose Tissue Following Weight Loss Induced by Diet or Bariatric Surgery by van der Kolk, Birgitta W, Muniandy, Maheswary, Kaminska, Dorota, Alvarez, Marcus, Ko, Arthur, Miao, Zong, Valsesia, Armand, Langin, Dominique, Vaittinen, Maija, Pääkkönen, Mirva, Jokinen, Riikka, Kaye, Sanna, Heinonen, Sini, Virtanen, Kirsi A, Andersson, Daniel P, Männistö, Ville, Saris, Wim H, Astrup, Arne, Rydén, Mikael, Blaak, Ellen E, Pajukanta, Päivi, Pihlajamäki, Jussi, Pietiläinen, Kirsi H

“…Abstract Context Mitochondria are essential for cellular energy homeostasis, yet their role in subcutaneous adipose tissue (SAT) during different types of…”
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Plasma lipid profiling of tissue-specific insulin resistance in human obesity by van der Kolk, Birgitta W., Vogelzangs, Nicole, Jocken, Johan W. E., Valsesia, Armand, Hankemeier, Thomas, Astrup, Arne, Saris, Wim H. M., Arts, Ilja C. W., van Greevenbroek, Marleen M. J., Blaak, Ellen E.

“…Background/Objectives Obesity-associated insulin resistance (IR) may develop in multiple organs, representing different aetiologies towards cardiometabolic…”
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Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study by Lapatto, Helena A K, Kuusela, Minna, Heikkinen, Aino, Muniandy, Maheswary, van der Kolk, Birgitta W, Gopalakrishnan, Swetha, Pöllänen, Noora, Sandvik, Martin, Schmidt, Mark S, Heinonen, Sini, Saari, Sina, Kuula, Juho, Hakkarainen, Antti, Tampio, Janne, Saarinen, Tuure, Taskinen, Marja-Riitta, Lundbom, Nina, Groop, Per-Henrik, Tiirola, Marja, Katajisto, Pekka, Lehtonen, Marko, Brenner, Charles, Kaprio, Jaakko, Pekkala, Satu, Ollikainen, Miina, Pietiläinen, Kirsi H, Pirinen, Eija

“…Nicotinamide adenine dinucleotide (NAD ) precursor nicotinamide riboside (NR) has emerged as a promising compound to improve obesity-associated mitochondrial…”
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Angiopoietin-Like Protein 4 and Postprandial Skeletal Muscle Lipid Metabolism in Overweight and Obese Prediabetics by van der Kolk, Birgitta W, Goossens, Gijs H, Jocken, Johan W, Kersten, Sander, Blaak, Ellen E

“…Context: Angiopoietin-like protein 4 (ANGPTL4) decreases plasma triacylglycerol (TAG) clearance by inhibiting lipoprotein lipase (LPL) and may contribute to…”
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Adipose Tissue Meal‐Derived Fatty Acid Uptake Before and After Diet‐Induced Weight Loss in Adults with Overweight and Obesity by Vink, Roel G., Roumans, Nadia J., van der Kolk, Birgitta W., Fazelzadeh, Parastoo, Boekschoten, Mark V., Mariman, Edwin C., van Baak, Marleen A.

“…Objective This study investigated whether diet‐induced weight loss alters indices of in vivo postprandial fat uptake in adipose tissue (AT) and whether these…”
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Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI by van der Kolk, Birgitta W., Saari, Sina, Lovric, Alen, Arif, Muhammad, Alvarez, Marcus, Ko, Arthur, Miao, Zong, Sahebekhtiari, Navid, Muniandy, Maheswary, Heinonen, Sini, Oghabian, Ali, Jokinen, Riikka, Jukarainen, Sakari, Hakkarainen, Antti, Lundbom, Jesper, Kuula, Juho, Groop, Per-Henrik, Tukiainen, Taru, Lundbom, Nina, Rissanen, Aila, Kaprio, Jaakko, Williams, Evan G., Zamboni, Nicola, Mardinoglu, Adil, Pajukanta, Päivi, Pietiläinen, Kirsi H.

“…Tissue-specific mechanisms prompting obesity-related development complications in humans remain unclear. We apply multiomics analyses of subcutaneous adipose…”
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Baseline gene expression in subcutaneous adipose tissue predicts diet-induced weight loss in individuals with obesity by Oghabian, Ali, van der Kolk, Birgitta W, Marttinen, Pekka, Valsesia, Armand, Langin, Dominique, Saris, W H, Astrup, Arne, Blaak, Ellen E, Pietiläinen, Kirsi H

“…Weight loss effectively reduces cardiometabolic health risks among people with overweight and obesity, but inter-individual variability in weight loss…”
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Subcutaneous adipose tissue and skeletal muscle mitochondria following weight loss by van der Kolk, Birgitta W., Pirinen, Eija, Nicoll, Rachel, Pietiläinen, Kirsi H., Heinonen, Sini

“…Bariatric surgery and dieting have distinct effects on mitochondrial metabolism in adipose tissue and skeletal muscle.In adipose tissue, bariatric surgery may…”
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Effect of diet‐induced weight loss on angiopoietin‐like protein 4 and adipose tissue lipid metabolism in overweight and obese humans by Kolk, Birgitta W., Vink, Roel G., Jocken, Johan W. E., Roumans, Nadia J. T., Goossens, Gijs H., Mariman, Edwin C. M., Baak, Marleen A., Blaak, Ellen E.

“…Angiopoietin‐like protein 4 (ANGPTL4) plays a role in lipid partitioning by inhibiting lipoprotein lipase (LPL)‐dependent plasma clearance of triacylglycerol…”
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Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits by Brotman, Sarah M, Oravilahti, Anniina, Rosen, Jonathan D, Alvarez, Marcus, Heinonen, Sini, van der Kolk, Birgitta W, Fernandes Silva, Lilian, Perrin, Hannah J, Vadlamudi, Swarooparani, Pylant, Cortney, Deochand, Sonia, Basta, Patricia V, Valone, Jordan M, Narain, Morgan N, Stringham, Heather M, Boehnke, Michael, Kuusisto, Johanna, Love, Michael I, Pietiläinen, Kirsi H, Pajukanta, Päivi, Laakso, Markku, Mohlke, Karen L

“…Understanding differences in adipose gene expression between individuals with different levels of clinical traits may reveal the genes and mechanisms leading…”
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Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans by van der Kolk, Birgitta W, Kalafati, Marianthi, Adriaens, Michiel, van Greevenbroek, Marleen M J, Vogelzangs, Nicole, Saris, Wim H M, Astrup, Arne, Valsesia, Armand, Langin, Dominique, van der Kallen, Carla J H, Eussen, Simone J P M, Schalkwijk, Casper G, Stehouwer, Coen D A, Goossens, Gijs H, Arts, Ilja C W, Jocken, Johan W E, Evelo, Chris T, Blaak, Ellen E

“…Obesity-related insulin resistance (IR) may develop in multiple organs, representing various etiologies for cardiometabolic diseases. We identified abdominal…”
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Altered skeletal muscle fatty acid handling is associated with the degree of insulin resistance in overweight and obese humans by van der Kolk, Birgitta W., Goossens, Gijs H., Jocken, Johan W., Blaak, Ellen E.

“…Introduction/hypothesis Disturbances in skeletal muscle fatty acid (FA) handling may contribute to the development and progression of whole-body insulin…”
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