Search Results - "van der Klein, Pieter A. M"

5‘-O-Alkyl Ethers of N,2-Substituted Adenosine Derivatives:  Partial Agonists for the Adenosine A1 and A3 Receptors by van Tilburg, Erica W, van der Klein, Pieter A. M, von Frijtag Drabbe Künzel, Jacobien, de Groote, Miriam, Stannek, Christina, Lorenzen, Anna, IJzerman, Ad P

“…New N,5‘-di- and N,2,5‘-trisubstituted adenosine derivatives were synthesized in good overall yields. Appropriate 5-O-alkyl-substituted ribose moieties were…”
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Allosteric Modulation of the Adenosine A1 Receptor. Synthesis and Biological Evaluation of Novel 2-Amino-3-benzoylthiophenes as Allosteric Enhancers of Agonist Binding by van der Klein, Pieter A. M, Kourounakis, Angeliki P, IJzerman, Ad P

“…Novel allosteric enhancers of agonist binding to the rat adenosine A1 receptor are described. The lead compound for the new series was PD 81,723…”
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Synthesis and biological evaluation of disubstituted N6-cyclopentyladenine analogues: the search for a neutral antagonist with high affinity for the adenosine A1 receptor by de Ligt, Rianne A.F., van der Klein, Pieter A.M., von Frijtag Drabbe Künzel, Jacobien K., Lorenzen, Anna, Ait El Maate, Fatna, Fujikawa, Shelly, van Westhoven, Rosemarijn, van den Hoven, Thijs, Brussee, Johannes, IJzerman, Ad P.

“…Novel 3,8- and 8,9-disubstituted N6-cyclopentyladenine derivatives were synthesised in moderate overall yield from 6-chloropurine. The derivatives were made in…”
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Allosteric Modulation of the Adenosine A 1 Receptor. Synthesis and Biological Evaluation of Novel 2-Amino-3-benzoylthiophenes as Allosteric Enhancers of Agonist Binding by van der Klein, Pieter A. M., Kourounakis, Angeliki P., IJzerman, Ad P.

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5‘- O -Alkyl Ethers of N ,2-Substituted Adenosine Derivatives:  Partial Agonists for the Adenosine A 1 and A 3 Receptors by van Tilburg, Erica W., van der Klein, Pieter A. M., von Frijtag Drabbe Künzel, Jacobien, de Groote, Miriam, Stannek, Christina, Lorenzen, Anna, IJzerman, Ad P.

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