Search Results - "van der Hoek, Steven A."
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Engineering precursor supply for the high-level production of ergothioneine in Saccharomyces cerevisiae
Published in Metabolic engineering (01-03-2022)“…Ergothioneine (ERG) is an unusual sulfur-containing amino acid. It is a potent antioxidant, which shows great potential for ameliorating neurodegenerative and…”
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The biology of ergothioneine, an antioxidant nutraceutical
Published in Nutrition research reviews (01-12-2020)“…Ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent antioxidant activities. It is synthesised by a variety of microbes,…”
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Engineering ergothioneine production in Yarrowia lipolytica
Published in FEBS letters (01-05-2022)“…Ergothioneine is a naturally occurring antioxidant that has shown potential in ameliorating neurodegenerative and cardiovascular diseases. In this study, we…”
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Deorphanizing solute carriers in Saccharomyces cerevisiae for secondary uptake of xenobiotic compounds
Published in Frontiers in microbiology (2024)“…The exchange of small molecules between the cell and the environment happens through transporter proteins. Besides nutrients and native metabolic products,…”
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Engineering the Yeast Saccharomyces cerevisiae for the Production of L-(+)-Ergothioneine
Published in Frontiers in bioengineering and biotechnology (11-10-2019)“…L-(+)-Ergothioneine (ERG) is an unusual, naturally occurring antioxidant nutraceutical that has been shown to help reduce cellular oxidative damage. Humans do…”
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Transporter engineering in microbial cell factories: the ins, the outs, and the in-betweens
Published in Current opinion in biotechnology (01-12-2020)“…[Display omitted] •Transporter proteins are essential for substrate uptake, product export, and intercompartmental metabolite exchange.•Transporter activity of…”
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