Search Results - "van der Hee, Bart"
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Impact of Fermentable Protein, by Feeding High Protein Diets, on Microbial Composition, Microbial Catabolic Activity, Gut Health and beyond in Pigs
Published in Microorganisms (Basel) (05-11-2020)“…In pigs, high protein diets have been related to post-weaning diarrhoea, which may be due to the production of protein fermentation metabolites that were shown…”
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Microbial Regulation of Host Physiology by Short-chain Fatty Acids
Published in Trends in microbiology (Regular ed.) (01-08-2021)“…Our ancestral diet consisted of much more nondigestible fiber than that of many societies today. Thus, from an evolutionary perspective the human genome and…”
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Identification of plasminogen-binding sites in Streptococcus suis enolase that contribute to bacterial translocation across the blood-brain barrier
Published in Frontiers in cellular and infection microbiology (22-02-2024)“…is an emerging zoonotic pathogen that can cause invasive disease commonly associated with meningitis in pigs and humans. To cause meningitis, must cross the…”
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Congruence of Transcription Programs in Adult Stem Cell-Derived Jejunum Organoids and Original Tissue During Long-Term Culture
Published in Frontiers in cell and developmental biology (02-07-2020)“…The emergence of intestinal organoids, as a stem cell-based self-renewable model system, has led to many studies on intestinal development and cell-cell…”
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Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet
Published in Molecular nutrition & food research (01-08-2017)“…Scope Metabolic flexibility is the ability to switch metabolism between carbohydrate oxidation (CHO) and fatty acid oxidation (FAO) and is a biomarker for…”
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High-level integration of murine intestinal transcriptomics data highlights the importance of the complement system in mucosal homeostasis
Published in BMC genomics (30-12-2019)“…The mammalian intestine is a complex biological system that exhibits functional plasticity in its response to diverse stimuli to maintain homeostasis. To…”
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Effects of undigested protein-rich ingredients on polarised small intestinal organoid monolayers
Published in Journal of animal science and biotechnology (18-05-2020)“…Here, we describe the use of monolayers of intestinal epithelial cells derived from intestinal organoids and transcriptomics to investigate the direct effects…”
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Assessing seromuscular layer and serosa removal on intestinal permeability measurements in weaned piglet everted sac segments
Published in Journal of animal science (03-01-2024)“…The integrity of the intestinal barrier is crucial for regulating the passage of pathogens and toxins, while facilitating nutrient absorption. The everted gut…”
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Organoid Based Models to Study the Role of Gut Microbiota Metabolites in Post-Weaning Diarrhea
Published 01-01-2023“…This project was part of a larger consortium funded by the Dutch Research Council (NWO) and DSM, investigating the contribution of protein fermentation in farm…”
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Dissertation -
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Transport of perfluoroalkyl substances across human induced pluripotent stem cell-derived intestinal epithelial cells in comparison with primary human intestinal epithelial cells and Caco-2 cells
Published in Archives of toxicology (01-11-2024)“…Humans can be exposed to per- and polyfluoroalkyl substances (PFASs) via many exposure routes, including diet, which may lead to several adverse health…”
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Multi-country metabolic signature discovery for chicken health classification
Published in Metabolomics (02-02-2023)“…Introduction To decrease antibiotic resistance, their use as growth promoters in the agricultural sector has been largely abandoned. This may lead to decreased…”
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Effects of undigested protein-rich ingredients on polarised small intestinal organoid monolayers
Published in 畜牧与生物技术杂志(英文版) (2020)“…Here, we describe the use of monolayers of intestinal epithelial cells derived from intestinal organoids and transcriptomics to investigate the direct effects…”
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Journal Article