Search Results - "van der Gun, J."

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    Decreased sensitivity to diphtheria toxin of Vero cells cultured in serum-free medium by Piersma, S.J., van der Gun, J.W., Hendriksen, C.F.M., Thalen, M.

    Published in Biologicals (01-06-2005)
    “…Vero cell cultures are used in the quality control of Diphtheria vaccines: to estimate vaccine potency and to determine residual toxicity and reversion to…”
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    Journal Article
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    The use of the in vitro toxin binding inhibition (ToBI) test for the estimation of the potency of tetanus toxoid by Hendriksen, C F, van der Gun, J W, Marsman, F R, Kreeftenberg, J G

    Published in Biologicals (01-01-1991)
    “…The in vitro toxin binding inhibition (ToBI) test was used to determine antitoxin responses in mice immunized with tetanus toxoid. The ToBI test showed good…”
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    Journal Article
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    Validation of the combined toxin-binding inhibition test for determination of neutralizing antibodies against tetanus and diphtheria toxins in a vaccine field study in Viet Nam by HONG, H. A, KE, N. T, NHON, T. N, THINH, N. D, VAN DER GUN, J. W, HENDRIKS, J. T, KREEFTENBERG, J. G

    Published in Bulletin of the World Health Organization (01-05-1996)
    “…Determination of seroconversion and measurement of protective antibody levels in children against vaccine components are essential for gauging and monitoring…”
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    Combined estimation of tetanus and diphtheria antitoxin in human sera by the in vitro Toxin-Binding Inhibition (ToBI) test by Hendriksen, C F, van der Gun, J W, Kreeftenberg, J G

    “…The use of the principle of inhibition of toxin binding to an antitoxin coated immunoassay plate as described in a previous paper for tetanus antitoxin…”
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    Journal Article
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    Interlaboratory validation of in vitro serological assay systems to assess the potency of tetanus toxoid in vaccines for veterinary use by Hendriksen, C F, Woltjes, J, Akkermans, A M, van der Gun, J W, Marsman, F R, Verschure, M H, Veldman, K

    Published in Biologicals (01-09-1994)
    “…An interlaboratory validation study was carried out in seven laboratories to evaluate the suitability of in vitro serological assay systems for the assessment…”
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    Journal Article
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    Extending the Link Transmission Model with non-triangular fundamental diagrams and capacity drops by van der Gun, Jeroen P.T., Pel, Adam J., van Arem, Bart

    “…•We extend the Link Transmission Model with continuous concave fundamental diagrams.•We extend LWR theory with inverted-lambda style diagrams having capacity…”
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    Mobility impacts of automated driving and shared mobility: explorative model and case study of the province of north Holland by Snelder, Maaike, Wilmink, Isabel, Van der Gun, Jeroen, Bergveld, Hendrik Jan, Hoseini, Parvin, Van Arem, Bart

    “…This paper presents a model specifically developed to explore the mobility impacts of connected and automated driving and shared mobility. It is an explorative…”
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    Evaluation of toxin neutralisation in test systems for diphtheria antibody assessment by Vandenberg, J, van der Gun, J W, Hendriksen, C F

    “…Over the past years, various authors have reported that the amount of toxin used in toxin neutralisation (TN) assays for diphtheria appears to influence the…”
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    Journal Article
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    Collaborative Study on Test Systems to Assess Toxicity of Whole Cell Pertussis Vaccine by van Straaten-van de Kappelle, Ineke, van der Gun, Johan W., Marsman, Frits R., Hendriksen, Coenraad F.M., van de Donk, Huib J.M.

    Published in Biologicals (01-03-1997)
    “…A collaborative study has been carried out to establish the precision and accuracy of five test systems for the assessment of the toxicity of whole cell…”
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    Evaluation of two serological methods for potency testing of whole cell pertussis vaccines by von Hunolstein, C, Gomez Miguel, M J, Pezzella, C, Scopetti, F, Behr-Gross, M-E, Halder, M, Hoffmann, S, Levels, L, van der Gun, J, Hendriksen, C

    Published in Pharmeuropa bio (01-12-2008)
    “…The European Pharmacopoeia (Ph. Eur.) and the World Health Organization (WHO) require the performance of extensive quality control testing including a potency…”
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    Acellular and whole cell pertussis vaccines protect against the lethal effects of intracerebral challenge by two different T-cell dependent humoral routes by Wiertz, E J, Walvoort, H C, Van Loveren, H, Van Straaten-Van De Kappelle, I, Van Der Gun, J W, Kreeftenberg, J G

    Published in Biologicals (01-07-1990)
    “…Athymic (nu/nu) and euthymic (+/nu) BALB/c mice were immunized with a whole cell pertussis vaccine or with an acellular vaccine which contained detoxified…”
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    Journal Article
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    Validation of the toxin-binding inhibition (ToBI) test for the estimation of the potency of the tetanus toxoïd component in vaccines by van der Gun, J, Akkermans, A, Hendriksen, C, van de Donk, H

    “…A validation study has been performed to determine the suitability of the toxin binding inhibition (ToBI) test for the serological estimation of the potency of…”
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    A mouse model to estimate the potency of the diphtheria component in combined vaccines by Kreeftenberg, J G, van der Gun, J, Marsman, F R, van Asten, J A, Sekhuis, V M, Hendriksen, C F

    “…A mouse model is presented to estimate the potency of the diphtheria component in combined vaccines. In addition, a simplified mouse test is suggested for…”
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    An investigation of a mouse model to estimate the potency of the diphtheria component in vaccines by Kreeftenberg, J G, van der Gun, J, Marsman, F R, Sekhuis, V M, Bhandari, S K, Maheshwari, S C

    Published in Journal of biological standardization (01-01-1985)
    “…A mouse model to estimate the potency of the diphtheria toxoid components in vaccines using Vero cells to detect the neutralizing antibodies in the sera from…”
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    The effects of reductions in the numbers of animals used for the potency assay of the diphtheria and tetanus components of adsorbed vaccines by the methods of the European pharmacopoeia by Hendriksen, C F, van der Gun, J W, Marsman, F R, Kreeftenberg, J G

    Published in Journal of biological standardization (01-10-1987)
    “…Forty eight assays of adsorbed diphtheria vaccine and seven assays of adsorbed tetanus vaccine using either a lethal challenge (38 assays) or a serum…”
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    Sharing groundwater information, knowledge and experience on a worldwide scale by Gun, J. A. M. van der

    “…Information is a critical element for groundwater management, no matter what region. This paper further highlights this issue by examining global information…”
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    Book Chapter