Search Results - "van der Graaf, Adrianus C"
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SUL-151 Decreases Airway Neutrophilia as a Prophylactic and Therapeutic Treatment in Mice after Cigarette Smoke Exposure
Published in International journal of molecular sciences (08-05-2021)“…Chronic obstructive pulmonary disease (COPD) caused by cigarette smoke (CS) is featured by oxidative stress and chronic inflammation. Due to the poor efficacy…”
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Serotonin and dopamine protect from hypothermia/rewarming damage through the CBS/H2S pathway
Published in PloS one (27-07-2011)“…Biogenic amines have been demonstrated to protect cells from apoptotic cell death. Herein we show for the first time that serotonin and dopamine increase H(2)S…”
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Journal Article -
3
Safety, tolerability and toxicokinetics of the novel mitochondrial drug SUL-138 administered orally to rat and minipig
Published in Toxicology reports (01-06-2024)“…Noncommunicable Chronic Diseases (NCD) are a socioeconomic burden and considered one of the major health challenges for coming decades. Mitochondrial…”
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The 6-chromanol derivate SUL-109 enables prolonged hypothermic storage of adipose tissue-derived stem cells
Published in Biomaterials (01-03-2017)“…Abstract Encouraging advances in cell therapy research with adipose derived stem cells (ASC) require an effective short-term preservation method that provides…”
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5
The 6-hydroxychromanol derivative SUL-109 ameliorates renal injury after deep hypothermia and rewarming in rats
Published in Nephrology, dialysis, transplantation (01-12-2018)“…Mitochondrial dysfunction plays an important role in kidney damage in various pathologies, including acute and chronic kidney injury and diabetic nephropathy…”
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6
Serotonin and Dopamine Protect from Hypothermia/Rewarming Damage through the CBS/ H.sub.2S Pathway
Published in PloS one (27-07-2011)“…Biogenic amines have been demonstrated to protect cells from apoptotic cell death. Herein we show for the first time that serotonin and dopamine increase…”
Get full text
Journal Article