Search Results - "van der Giezen, Dionne M."
-
1
Loss of Endogenous Bone Morphogenetic Protein-6 Aggravates Renal Fibrosis
Published in The American journal of pathology (01-03-2011)“…Bone morphogenetic protein-6 (BMP-6) suppresses inflammatory genes in renal proximal tubular cells and regulates iron metabolism by inducing hepcidin. In…”
Get full text
Journal Article -
2
In mice, proteinuria and renal inflammatory responses to albumin overload are strain-dependent
Published in Nephrology, dialysis, transplantation (01-03-2006)“…Background. The availability of genetically modified mice has increased the need for relevant mouse models of renal disease, but widely used C57BL/6 mice often…”
Get full text
Journal Article -
3
A perinatal nitric oxide donor increases renal vascular resistance and ameliorates hypertension and glomerular injury in adult fawn-hooded hypertensive rats
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-06-2008)“…Enhancing perinatal nitric oxide (NO) availability persistently reduces blood pressure in spontaneously hypertensive rats. We hypothesize that this approach…”
Get more information
Journal Article -
4
Oxidative stress in obstructive nephropathy
Published in International journal of experimental pathology (01-06-2011)Get full text
Journal Article -
5
Temporary losartan or captopril in young SHR induces malignant hypertension despite initial normotension
Published in Kidney international (01-02-2004)“…Temporary losartan or captopril in young SHR induces malignant hypertension despite initial normotension. Exposure of normotensive rats to…”
Get full text
Journal Article -
6
Oxidative stress in obstructive nephropathy
Published in International journal of experimental pathology (01-06-2011)“…Summary Unilateral ureteric obstruction (UUO) is one of the most commonly applied rodent models to study the pathophysiology of renal fibrosis. This model…”
Get full text
Journal Article -
7
Hemizygous deletion of CTGF/CCN2 does not suffice to prevent fibrosis of the severely injured kidney
Published in Matrix biology (01-09-2012)“…Connective Tissue Growth Factor (CTGF/CCN2) is an important mediator of kidney fibrosis. Previous observations indicated that attenuation of CCN2 expression…”
Get full text
Journal Article -
8
Connective Tissue Growth Factor Is Involved in Structural Retinal Vascular Changes in Long-Term Experimental Diabetes
Published in The journal of histochemistry and cytochemistry (01-02-2014)“…Early retinal vascular changes in the development of diabetic retinopathy (DR) include capillary basal lamina (BL) thickening, pericyte loss and the…”
Get full text
Journal Article -
9
Perinatal L-Arginine and Antioxidant Supplements Reduce Adult Blood Pressure in Spontaneously Hypertensive Rats
Published in Hypertension (Dallas, Tex. 1979) (01-07-2004)“…Embryo cross-transplantation and cross-fostering between spontaneously hypertensive rats (SHR) and normotensive rats (WKY) suggest that perinatal environment…”
Get full text
Journal Article -
10
Perinatal Micronutrient Supplements Ameliorate Hypertension and Proteinuria in Adult Fawn-Hooded Hypertensive Rats
Published in American journal of hypertension (01-07-2010)“…Background In fawn-hooded hypertensive (FHH) rats, a model of hypertension, impaired preglomerular resistance, hyperfiltration, and progressive renal injury,…”
Get full text
Journal Article -
11
Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys
Published in The Journal of pathology (01-05-2011)“…Bone morphogenetic protein 7 (BMP7) is a key determinant of renal response to injury, exhibiting strong protective as well as regenerative potential in a…”
Get full text
Journal Article -
12
Protein restriction in lactation confers nephroprotective effects in the male rat and is associated with increased antioxidant expression
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-09-2007)“…Telomere shortening has been implicated in the aging process and various age-associated disorders, including renal disease. Moreover, oxidative stress has been…”
Get more information
Journal Article -
13
Implementation of accurate and fast DNA cytometry by confocal microscopy in 3D
Published in Analytical cellular pathology (Amsterdam) (2005)“…DNA cytometry is a powerful method for measuring genomic instability. Standard approaches that measure DNA content of isolated cells may induce selection bias…”
Get full text
Journal Article -
14
-
15
Oxidative stress in obstructive nephropathy: Oxidative stress in nephropathy
Published in International journal of experimental pathology (01-06-2011)Get full text
Journal Article