Search Results - "van der Geyten, Serge"

Development of interventions for the secondary prevention of Alzheimer's dementia: the European Prevention of Alzheimer's Dementia (EPAD) project by Ritchie, Craig W, Prof, Molinuevo, José Luis, MD, Truyen, Luc, MD, Satlin, Andrew, MD, Van der Geyten, Serge, PhD, Lovestone, Simon, Prof

“…Summary Alzheimer's dementia affects more than 40 million people worldwide with substantial increases in prevalence anticipated. Interventions that either…”
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The European Prevention of Alzheimer's Dementia Programme: An Innovative Medicines Initiative-funded partnership to facilitate secondary prevention of Alzheimer's disease dementia by Saunders, Stina, Gregory, Sarah, Clement, Matthew H S, Birck, Cindy, van der Geyten, Serge, Ritchie, Craig W

“…Tens of millions of people worldwide will develop Alzheimer's disease (AD), and only by intervening early in the preclinical disease can we make a fundamental…”
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Time‐to‐event clinical trial designs: Existing evidence and remaining concerns by Kerr, Wesley T., Auvin, Stéphane, Van der Geyten, Serge, Kenney, Christopher, Novak, Gerald, Fountain, Nathan B., Grzeskowiak, Caitlin, French, Jacqueline A.

“…Well‐designed placebo‐controlled clinical trials are critical to the development of novel treatments for epilepsy, but their design has not changed for…”
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Type 2 Iodothyronine Deiodinase Is Essential for Thyroid Hormone-Dependent Embryonic Development and Pigmentation in Zebrafish by Walpita, Chaminda N, Crawford, Alexander D, Janssens, Els D. R, Van der Geyten, Serge, Darras, Veerle M

“…Despite the known importance of thyroid hormones (THs) in vertebrate growth and development, the role of tissue-specific TH activation in early embryogenesis…”
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Perchlorate versus other environmental sodium/iodide symporter inhibitors: potential thyroid-related health effects by De Groef, Bert, Decallonne, Brigitte R, Van der Geyten, Serge, Darras, Veerle M, Bouillon, Roger

“…Objective: Perchlorate is a known competitive inhibitor of the sodium/iodide symporter (NIS). Possible thyroid-related effects of environmental perchlorate…”
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Role of corticotropin-releasing hormone as a thyrotropin-releasing factor in non-mammalian vertebrates by De Groef, Bert, Van der Geyten, Serge, Darras, Veerle M., Kühn, Eduard R.

“…The finding that thyrotropin-releasing hormone does not always act as a thyrotropin (TSH)-releasing factor in non-mammalian vertebrates has led researchers to…”
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Low submetamorphic doses of dexamethasone and thyroxine induce complete metamorphosis in the axolotl ( Ambystoma mexicanum) when injected together by Kühn, Eduard R, Groef, Bert De, Grommen, Sylvia V.H, Geyten, Serge Van der, Darras, Veerle M

“…Entanglement of functions between the adrenal (or interrenal) and thyroid axis has been well described for all vertebrates and can be tracked down up to the…”
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The effect of 3,5,3′-triiodothyronine supplementation on zebrafish ( Danio rerio ) embryonic development and expression of iodothyronine deiodinases and thyroid hormone receptors by Walpita, Chaminda N, Van der Geyten, Serge, Rurangwa, Eugene, Darras, Veerle M

“…Abstract The importance of thyroid hormones (TH) for embryonic development has long been shown in many vertebrates, but is not yet established in pre-hatch…”
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Chicken Ghrelin: Purification, cDNA Cloning, and Biological Activity by Kaiya, Hiroyuki, van der Geyten, Serge, Kojima, Masayasu, Hosoda, Hiroshi, Kitajima, Yasuo, Matsumoto, Masaru, Geelissen, Sofie, Darras, Veerle M, Kangawa, Kenji

“…In this study, we report the purification, cDNA cloning, and characterization of the novel growth hormone-releasing peptide, ghrelin, in the chicken (Gallus…”
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Tissue Thyroid Hormone Levels in Critical Illness by Peeters, Robin P., van der Geyten, Serge, Wouters, Pieter J., Darras, Veerle M., van Toor, Hans, Kaptein, Ellen, Visser, Theo J., Van den Berghe, Greet

“…Context: Pronounced alterations in serum thyroid hormone levels occur during critical illness. T3 decreases and rT3 increases, the magnitudes of which are…”
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Thyroid hormone deiodination in birds by Darras, Veerle M, Verhoelst, Carla H J, Reyns, Geert E, Kühn, Eduard R, Van der Geyten, Serge

“…Because the avian thyroid gland secretes almost exclusively thyroxine (T4), the availability of receptor-active 3,3',5-triiodothyronine (T3) has to be…”
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Pre- and postprandial changes in plasma hormone and metabolite levels and hepatic deiodinase activities in meal-fed broiler chickens by Buyse, Johan, Janssens, Kristel, Van der Geyten, Serge, Van As, Pieter, Decuypere, Eddy, Darras, Veerle M.

“…The present study aimed to study the effects of food deprivation and subsequent postprandial changes in plasma somatotrophic and thyrotrophic hormone levels…”
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Molecular Cloning and Developmental Expression of Corticotropin-Releasing Factor in the Chicken by Vandenborne, Kristien, De Groef, Bert, Geelissen, Sofie M. E, Boorse, Graham C, Denver, Robert J, Kühn, Eduard R, Darras, Veerle M, Van der Geyten, Serge

“…We have characterized the structure of the chicken corticotropin-releasing factor (CRF) gene through cDNA cloning and genomic sequence analysis, and we…”
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Hypothyroidism Induces Type I Iodothyronine Deiodinase Expression in Tilapia Liver by Van der Geyten, Serge, Toguyeni, Aboubacar, Baroiller, Jean-Francois, Fauconneau, Benoit, Fostier, Alexis, Sanders, Jo P., Visser, Theo J., Kühn, Eduard R., Darras, Veerle M.

“…In the current study, the authors examined the effects of experimentally induced hypothyroidism on peripheral thyroid hormone metabolism and growth in two…”
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Corticosterone-induced negative feedback mechanisms within the hypothalamo–pituitary–adrenal axis of the chicken by Vandenborne, Kristien, De Groef, Bert, Geelissen, Sofie M E, Kühn, Eduard R, Darras, Veerle M, Van der Geyten, Serge

“…This paper reports the results of in vivo and in vitro experiments on the feedback effects of corticosterone on the hypothalamo–pituitary–adrenal axis in…”
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Dietary low-glucosinolate rapeseed meal affects thyroid status and nutrient utilization in rainbow trout (Oncorhynchus mykiss) by Burel, Christine, Boujard, Thierry, Escaffre, Anne-Marie, Kaushik, Sadasivam J., Boeuf, Gilles, Mol, Koen A., Van der Geyten, Serge, Kühn, Eduard R.

“…Two rapeseed (Brassica napus) meals, RM1 and RM2, with two levels of glucosinolates (GLS; 5 and 41 μmol/g DM respectively) were incorporated at the levels of…”
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Corticotropin-releasing hormone-mediated metamorphosis in the neotenic axolotl Ambystoma mexicanum: Synergistic involvement of thyroxine and corticoids on brain type II deiodinase by Kühn, Eduard R., De Groef, Bert, Van der Geyten, Serge, Darras, Veerle M.

“…In the present study, morphological changes leading to complete metamorphosis have been induced in the neotenic axolotl Ambystoma mexicanum using a…”
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Cloning and hypothalamic distribution of the chicken thyrotropin-releasing hormone precursor cDNA by Vandenborne, Kristien, Roelens, Simon A, Darras, Veerle M, Kühn, Eduard R, Van der Geyten, Serge

“…In this paper we report the cloning of the chicken preprothyrotropin-releasing hormone (TRH) cDNA and the study of its hypothalamic distribution. Chicken…”
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Characterization of a Propylthiouracil-Insensitive Type I Iodothyronine Deiodinase by Sanders, Jo P., Van der Geyten, Serge, Kaptein, Ellen, Darras, Veerle M., Kühn, Eduard R., Leonard, Jack L., Visser, Theo J.

“…Abstract Mammalian type I iodothyronine deiodinase (D1) activates and inactivates thyroid hormone by outer ring deiodination (ORD) and inner ring deiodination…”
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Characterization of Iodothyronine Outer Ring and Inner Ring Deiodinase Activities in the Blue Tilapia, Oreochromis Aureus by Mol, Koen A, van der Geyten, Serge, Darras, Veerle M, Visser, Theo J, Kühn, Eduard R

“…The presence of iodothyronine deiodinases was investigated in the different tissues of blue tilapia (Oreochromis aureus), and their biochemical properties were…”
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