Search Results - "van der Eb, M M"

Recombinant adenoviral vectors have adjuvant activity and stimulate T cell responses against tumor cells by GEUTSKENS, S. B, VAN DER EB, M. M, PLOMP, A. C, JONGES, L. E, CRAMER, S. J, ENSINK, N. G, KUPPEN, P. J. K, HOEBEN, R. C

“…The host-immune response against adenoviruses forms a major obstacle for their use as gene therapy vectors for treatment of genetic defects. None the less,…”
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Severe hepatic dysfunction after adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene and ganciclovir administration by VAN DER EB, M. M, CRAMER, S. J, VERGOUWE, Y, SCHAGEN, F. H. E, VAN KRIEKEN, J. H. J. M, VAN DER EB, A. J, RINKES, I. H. M. B, VAN DE VELDE, C. J. H, HOEBEN, R. C

“…The use of so-called 'suicide' genes to activate prodrugs has been effective in animal models for several solid tumor types and is now in phase I and II…”
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Specific tumor-cell killing with adenovirus vectors containing the apoptin gene by Pietersen, A M, van der Eb, M M, Rademaker, H J, van den Wollenberg, D J, Rabelink, M J, Kuppen, P J, van Dierendonck, J H, van Ormondt, H, Masman, D, van de Velde, C J, van der Eb, A J, Hoeben, R C, Noteborn, M H

“…Specificity is an essential prerequisite for cancer gene therapy. Recently we described that apoptin, a protein of 121 amino acids which is derived from the…”
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Gene therapy with Apoptin induces regression of xenografted human hepatomas by van der Eb, Marjolijn M, Pietersen, Alexandra M, Speetjens, Frank M, Kuppen, Peter J K, van de Velde, Cornelis J H, Noteborn, Mathieu H M, Hoeben, Rob C

“…The chicken anemia virus-derived Apoptin protein shows remarkable specificity; namely, it induces apoptosis in tumor cells, but not in normal diploid cells. We…”
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Tumor structure and extracellular matrix as a possible barrier for therapeutic approaches using immune cells or adenoviruses in colorectal cancer by Kuppen, P J, van der Eb, M M, Jonges, L E, Hagenaars, M, Hokland, M E, Nannmark, U, Goldfarb, R H, Basse, P H, Fleuren, G J, Hoeben, R C, van de Velde, C J

“…In this article we report about the role that tumor structure and extracellular matrix (ECM) may play in immunotherapy and in gene therapy using adenoviruses…”
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Isolated-organ perfusion for local gene delivery : efficient adenovirus-mediated gene transfer into the liver by DE ROOS, W. K, FALLAUX, F. J, MARINELLI, A. W. K. S, LAZARIS-KARATZAS, A, ALTING VON GEUSAU, B, VAN DER EB, M. M, CRAMER, S. J, TERPSTRA, O. T, HOEBEN, R. C

“…Targeted gene delivery is essential for gene therapy involving in vivo gene transfer. In the present study we analyzed the efficiency and tissue-specificity of…”
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Ganciclovir nucleotides accumulate in mitochondria of rat liver cells expressing the herpes simplex virus thymidine kinase gene by van der Eb, Marjolijn M., Geutskens, Sacha B., van Kuilenburg, André B. P., van Lenthe, Henk, van Dierendonck, Jan-Hein, Kuppen, Peter J. K., van Ormondt, Hans, van de Velde, Cornelis J. H., Wanders, Ronald J. A., van Gennip, Albert H., Hoeben, Rob C.

“…Background Ganciclovir exhibits broad‐spectrum activity against DNA viruses such as cytomegaloviruses, herpes simplex viruses, varicella‐zoster virus,…”
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Reverse smoking as a risk factor for palatal cancer: a cross-sectional study in rural Andhra Pradesh, India by van der Eb, M M, Leyten, E M, Gavarasana, S, Vandenbroucke, J P, Kahn, P M, Cleton, F J

“…A cross-sectional study of reverse smoking and its association with pre-malignant and malignant lesions of the palate was conducted in the north coastal areas…”
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Factors impeding efficient expression of factor VIII complementary DNA minigenes by Hoeben, R C, Fallaux, F J, Schagen, F H, van der Eb, M M, van Ormondt, H, van der Eb, A

“…Haemophilia A is a bleeding disorder that affects approximately 1 in 10,000 males. It is caused by a deficiency of functional blood-clotting factor VIII…”
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Towards gene therapy for colorectal liver metastases by van der Eb, M M, Hoeben, R C, van de Velde, C J

“…Hepatic gene therapy may provide a new approach to treating hepatic malignancies. A promising strategy involves the infection of tumor and liver cells with…”
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Association of Hospital Volume with Perioperative Mortality of Endovascular Repair of Complex Aortic Aneurysms: A Nationwide Cohort Study by Alberga, Anna J., von Meijenfeldt, Gerdine C. I., Rastogi, Vinamr, de Bruin, Jorg L., Wever, Jan J., van Herwaarden, Joost A., Hamming, Jaap F., Hazenberg, Constantijn E. V. B., van Schaik, Jan, Mees, Barend M. E., van der Laan, Maarten J., Zeebregts, Clark J., Schurink, Geert W. H., Verhagen, Hence J. M.

“…We evaluate nationwide perioperative outcomes of complex EVAR and assess the volume-outcome association of complex EVAR. Endovascular treatment with…”
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Saccular Abdominal Aortic Aneurysms: Patient Characteristics, Clinical Presentation, Treatment, and Outcomes in the Netherlands by Karthaus, Eleonora G, Tong, Thaïs M L, Vahl, Anco, Hamming, Jaap F

“…OBJECTIVE:The aim of this was to analyze differences between saccular-shaped abdominal aortic aneurysms (SaAAAs) and fusiform abdominal aortic aneurysms…”
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Delivery of anticancer drugs via isolated hepatic perfusion: A promising strategy in the treatment of irresectable liver metastases? by Vahrmeijer, Alexander L., van der Eb, Marjolijn M., van Dierendonck, Jan Hein, Kuppen, Peter J. K., van de Velde, Cornelis J. H.

“…The prognosis of patients with irresectable liver metastases derived from colorectal cancer is invariably poor; unfortunately, these tumours show only minor…”
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Nationwide Analysis of Patients Undergoing Iliac Artery Aneurysm Repair in the Netherlands by Jalalzadeh, Hamid, Indrakusuma, Reza, Koelemay, Mark J W, Balm, Ron, Van den Akker, L H, Van den Akker, P J, Akkersdijk, G J, Akkersdijk, G P, Akkersdijk, W L, van Andringa de Kempenaer, M G, Arts, C H, Avontuur, J A, Baal, J G, Bakker, O J, Balm, R, Barendregt, W B, Bender, M H, Bendermacher, B L, van den Berg, M, Berger, P, Beuk, R J, Blankensteijn, J D, Bleker, R J, Bockel, J H, Bodegom, M E, Bogt, K E, Boll, A P, Booster, M H, Borger van der Burg, B L, de Borst, G J, Bos-van Rossum, W T, Bosma, J, Botman, J M, Bouwman, L H, Breek, J C, Brehm, V, Brinckman, M J, van den Broek, T H, Brom, H L, de Bruijn, M T, de Bruin, J L, Brummel, P, van Brussel, J P, Buijk, S E, Buimer, M G, Burger, D H, Buscher, H C, den Butter, G, Cancrinus, E, Castenmiller, P H, Cazander, G, Coveliers, H M, Cuypers, P H, Daemen, J H, Dawson, I, Derom, A F, Dijkema, A R, Diks, J, Dinkelman, M K, Dirven, M, Dolmans, D E, van Doorn, R C, van Dortmont, L M, van der Eb, M M, Eefting, D, van Eijck, G J, Elshof, J W, Elsman, B H, van der Elst, A, van Engeland, M I, van Eps, R G, Faber, M J, de Fijter, W M, Fioole, B, Fritschy, W M, Geelkerken, R H, van Gent, W B, Glade, G J, Govaert, B, Groenendijk, R P, de Groot, H G, van den Haak, R F, de Haan, E F, Hajer, G F, Hamming, J F, van Hattum, E S, Hazenberg, C E, Hedeman Joosten, P P, Helleman, J N, van der Hem, L G, Hendriks, J M, van Herwaarden, J A, Heyligers, J M, Hinnen, J W, Hissink, R J, Ho, G H, den Hoed, P T, Hoedt, M T, van Hoek, F, Hoencamp, R

“…The new 2019 guideline of the European Society for Vascular Surgery (ESVS) recommends consideration for elective iliac artery aneurysm (eIAA) repair when the…”
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Side effects of suicide gene therapy by van der Eb, Marjolijn M, de Leeuw, Bertie, van der Eb, Alex J, Hoeben, Rob C

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Short-term outcomes of open surgical abdominal aortic aneurysm repair from the Dutch Surgical Aneurysm Audit by Geraedts, A C M, Alberga, A J, Koelemay, M J W, Verhagen, H J M, Vahl, A C, Balm, R

“…The sharp decrease in open surgical repair (OSR) for abdominal aortic aneurysm (AAA) has raised concerns about contemporary postoperative outcomes. The study…”
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Gene therapy for hemophilia: feasible in principle but not yet clinically applicable by van der Eb, M M, Schagen, F H, van Ormondt, H, Hoeben, R C

“…The current treatment of haemophiliacs consists of injection of concentrates of blood clotting factors VIII (haemophilia A) and IX (haemophilia B). The…”
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