Search Results - "van der Eb, A"

Cyclin D1 is an essential mediator of apoptotic neuronal cell death by Kranenburg, O., Eb, A. J., Zantema, A.

“…Many neurons in the developing nervous system undergo programmed cell death, or apoptosis. However, the molecular mechanism underlying this phenomenon is…”
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Severe hepatic dysfunction after adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene and ganciclovir administration by VAN DER EB, M. M, CRAMER, S. J, VERGOUWE, Y, SCHAGEN, F. H. E, VAN KRIEKEN, J. H. J. M, VAN DER EB, A. J, RINKES, I. H. M. B, VAN DE VELDE, C. J. H, HOEBEN, R. C

“…The use of so-called 'suicide' genes to activate prodrugs has been effective in animal models for several solid tumor types and is now in phase I and II…”
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The Chicken Anemia Virus-Derived Protein Apoptin Requires Activation of Caspases for Induction of Apoptosis in Human Tumor Cells by Danen-van Oorschot, A. A. A. M., van der Eb, A. J., Noteborn, M. H. M.

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Apoptin Induces Apoptosis in Human Transformed and Malignant Cells but not in Normal Cells by A. A. A. M. Danen-Van Oorschot, Fischer, D. F., Grimbergen, J. M., Klein, B., S.-M. Zhuang, Falkenburg, J. H. F., Backendorf, C., Quax, P. H. A., Van Der Eb, A. J., Noteborn, M. H. M.

“…The chicken anemia virus protein apoptin induces a p53-independent, Bcl-2-insensitive type of apoptosis in various human tumor cells. Here, we show that, in…”
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A single chicken anemia virus protein induces apoptosis by Noteborn, M.H.M, Todd, D, Verschueren, C.A.J, Gauw, H.W.F.M. de, Curran, W.L, Veldkamp, S, Douglas, A.J, McNulty, M.S, Eb, A.J. van der, Koch, G

“…Chicken anemia virus (CAV) causes cytopathogenic effects in chicken thymocytes and cultured transformed mononuclear cells via apoptosis. Early after infection…”
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Chicken anemia virus causes apoptosis of thymocytes after in vivo infection and of cell lines after in vitro infection by Jeurissen, S.H.M. (Central Veterinary Institute, Lelystad, Netherlands), Wagenaar, F, Pol, J.M.A, Eb, A.J. van der, Noteborn, M.H.M

“…After infection of 1-day-old chickens, chicken anemia virus (CAV) causes a complete depletion of the thymic cortex by day 14. Since cell death can be caused…”
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Specific tumor-cell killing with adenovirus vectors containing the apoptin gene by Pietersen, A M, van der Eb, M M, Rademaker, H J, van den Wollenberg, D J, Rabelink, M J, Kuppen, P J, van Dierendonck, J H, van Ormondt, H, Masman, D, van de Velde, C J, van der Eb, A J, Hoeben, R C, Noteborn, M H

“…Specificity is an essential prerequisite for cancer gene therapy. Recently we described that apoptin, a protein of 121 amino acids which is derived from the…”
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Insulin stimulation of gene expression mediated by p21ras activation by Burgering, B. M., Medema, R. H., Maassen, J. A., Wetering, M. L., Eb, A. J., McCormick, F., Bos, J. L.

“…In fibroblasts, insulin is a weak mitogen and does not induce expression of c‐fos, c‐jun or p33. However, increasing the expression levels of either normal…”
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Adenovirus E1A negatively and positively modulates transcription of AP‐1 dependent genes by dimer‐specific regulation of the DNA binding and transactivation activities of Jun by Hagmeyer, B.M., König, H., Herr, I., Offringa, R., Zantema, A., Eb, A., Herrlich, P., Angel, P.

“…Adenovirus E1A proteins inhibit expression of the collagenase gene but activate expression of the c‐jun gene. Both effects are mediated by TPA‐responsive…”
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Photodynamic treatment of adenoviral vectors with visible light: an easy and convenient method for viral inactivation by Schagen, F H, Moor, A C, Cheong, S C, Cramer, S J, van Ormondt, H, van der Eb, A J, Dubbelman, T M, Hoeben, R C

“…Recombinant adenovirus vectors are popular tools for gene transfer and gene therapy. However biosafety constraints require that all handling of the vectors and…”
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MDMX: a novel p53‐binding protein with some functional properties of MDM2 by Shvarts, A., Steegenga, W. T., Riteco, N., Laar, T., Dekker, P., Bazuine, M., Ham, R. C., Houven van Oordt, W., Hateboer, G., Eb, A. J., Jochemsen, A. G.

“…Here we report the isolation of a cDNA encoding a new p53‐associating protein. This new protein has been called MDMX on the basis of its structural similarity…”
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Ammonium sulphate precipitation of recombinant adenovirus from culture medium : an easy method to increase the total virus yield by SCHAGEN, F. H. E, RADEMAKER, H. J, RABELINK, M. J. W. E, VAN ORMONDT, H, FALLAUX, F. J, VAN DER EB, A. J, HOEBEN, R. C

“…In the majority of the methods for purifying and concentrating recombinant adenoviruses (rAds) the virus that is associated with the helper cells is harvested,…”
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Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53 by RAMOS, Yolande F. M, STAD, Robert, ATTEMA, Joline, PELTENBURG, Lucy T. C, VAN DER EB, Alex J, JOCHEMSEN, Aart G

“…It has been shown that the Hdmx gene is amplified in a subset of gliomas, but thus far, no data are available on HDMX protein expression in tumor cells. We now…”
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Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells by Schrier, P. I, Bernards, R, Vaessen, R. T. M. J, Houweling, A, van der Eb, A. J

“…Rat cells transformed by the highly oncogenic adenovirus 12 lack at least two cellular proteins which are present in cells transformed by the non-oncogenic…”
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The effect of Bcl-2 on Apoptin in 'normal' vs transformed human cells by Danen-Van Oorschot, A A, Zhang, Y, Erkeland, S J, Fischer, D F, van der Eb, A J, Noteborn, M H

“…Apoptosis is a programmed physiological process for eliminating superfluous, altered or even malignant cells. Apoptosis can be induced by many stimuli through…”
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Hdmx Stabilizes Mdm2 and p53 by Stad, R, Ramos, Y F, Little, N, Grivell, S, Attema, J, van Der Eb, A J, Jochemsen, A G

“…The Mdm2 protein is a key regulator of p53 activity and stability. Upon binding, Mdm2 inhibits the transcription regulatory activity of p53 and promotes its…”
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Molecular cloning and biological characterization of the human excision repair gene ERCC-3 by WEEDA, G, VAN HAM, R. C. A, MASUREL, R, WESTERVELD, A, ODIJK, H, DE WIT, J, BOOTSMA, D, VAN DER EB, A. J, HOEIJMAKERS, J. H. J

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH) by Vuuren, A.J., Vermeulen, W., Ma, L., Weeda, G., Appeldoorn, E., Jaspers, N.G., Eb, A.J., Bootsma, D., Hoeijmakers, J.H., Humbert, S.

“…ERCC3 was initially identified as a gene correcting the nucleotide excision repair (NER) defect of xeroderma pigmentosum complementation group B (XP‐B). The…”
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Autocrine growth and anchorage independence: two complementing Jun-controlled genetic programs of cellular transformation by van Dam, H, Huguier, S, Kooistra, K, Baguet, J, Vial, E, van der Eb, A J, Herrlich, P, Angel, P, Castellazzi, M

“…Cellular transformation can be achieved by constitutive activation of growth-regulatory signaling pathways, which, in turn, activate nuclear transcription…”
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Towards integrating vectors for gene therapy: expression of functional bacteriophage MuA and MuB proteins in mammalian cells by Schagen, F H, Rademaker, H J, Cramer, S J, van Ormondt, H, van der Eb, A J, van de Putte, P, Hoeben, R C

“…Bacteriophage Mu has one of the best studied, most efficient and largest transposition machineries of the prokaryotic world. To harness this attractive…”
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