Search Results - "van der Bijl, Ivo"
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The endosomal RIN2/Rab5C machinery prevents VEGFR2 degradation to control gene expression and tip cell identity during angiogenesis
Published in Angiogenesis (London) (01-08-2021)“…Sprouting angiogenesis is key to many pathophysiological conditions, and is strongly regulated by vascular endothelial growth factor (VEGF) signaling through…”
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Activation, function and content of platelets in burn patients
Published in Platelets (Edinburgh) (03-04-2019)“…Burn injury has severe impact on the physiologic homeostasis. Platelet counts show a distinct course post-burn injury, with a nadir at day 3 followed by a…”
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MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization
Published in Blood (11-06-2020)“…Megakaryoblastic leukemia 1 (MKL1) promotes the regulation of essential cell processes, including actin cytoskeletal dynamics, by coactivating serum response…”
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Fast in vitro protocol for the visualization and quantitative high-throughput analysis of sprouting angiogenesis by confocal microscopy
Published in STAR protocols (17-09-2021)“…We describe an optimized, cost-effective, reproducible, and robust protocol to study sprouting angiogenesis in glass-bottom 96-well plates by confocal…”
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Allogeneic platelet‐rich plasma (PRP) is superior to platelets or plasma alone in stimulating fibroblast proliferation and migration, angiogenesis, and chemotaxis as relevant processes for wound healing
Published in Transfusion (Philadelphia, Pa.) (01-11-2019)“…BACKGROUND Platelet‐rich plasma (PRP) is frequently used in the treatment of acute and chronic wounds. One of the major problems concerning the use of PRP is…”
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Variation in platelet‐rich plasma compositions used for wound healing indications
Published in Wound repair and regeneration (01-03-2021)“…At present, the role of platelet‐rich plasma (PRP) in burn and wound management is undefined. We present some of the evidence for PRP in wound healing and…”
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Combined immunodeficiency with severe inflammation and allergy caused by ARPC1B deficiency
Published in Journal of allergy and clinical immunology (01-07-2017)“…Arp2/3 gene deletions result in embryonic lethality in the mouse.2 The genetic defects in the regulatory proteins for cytoskeletal rearrangements cause…”
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Reciprocal integrin/integrin antagonism through kindlin-2 and Rho GTPases regulates cell cohesion and collective migration
Published in Matrix biology (01-11-2020)“…Collective cell behaviour during embryogenesis and tissue repair requires the coordination of intercellular junctions, cytoskeleton-dependent shape changes…”
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Reciprocal integrin/integrin antagonism through kindlin-2 and Rho GTPases regulates cell cohesion and collective migration: Integrin/integrin antagonism regulates collective cell behaviour
Published in Matrix biology (22-05-2020)“…Collective cell behaviour during embryogenesis and tissue repair requires the coordination of intercellular junctions, cytoskeleton-dependent shape changes…”
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