Search Results - "van den Worm, E"

SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum by Knoops, Kèvin, Kikkert, Marjolein, Worm, Sjoerd H E van den, Zevenhoven-Dobbe, Jessika C, van der Meer, Yvonne, Koster, Abraham J, Mommaas, A Mieke, Snijder, Eric J

“…Positive-strand RNA viruses, a large group including human pathogens such as SARS-coronavirus (SARS-CoV), replicate in the cytoplasm of infected host cells…”
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Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination by van den Worm, Sjoerd H E, Eriksson, Klara Kristin, Zevenhoven, Jessika C, Weber, Friedemann, Züst, Roland, Kuri, Thomas, Dijkman, Ronald, Chang, Guohui, Siddell, Stuart G, Snijder, Eric J, Thiel, Volker, Davidson, Andrew D

“…Severe acute respiratory syndrome (SARS) is a zoonotic disease caused by SARS-related coronavirus (SARS-CoV) that emerged in 2002 to become a global health…”
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SARS-coronavirus replication/transcription complexes are membrane-protected and need a host factor for activity in vitro by van Hemert, Martijn J, van den Worm, Sjoerd H E, Knoops, Kèvin, Mommaas, A Mieke, Gorbalenya, Alexander E, Snijder, Eric J

“…SARS-coronavirus (SARS-CoV) replication and transcription are mediated by a replication/transcription complex (RTC) of which virus-encoded, non-structural…”
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Development and RNA-Synthesizing Activity of Coronavirus Replication Structures in the Absence of Protein Synthesis by VAN DEN WORM, Sjoerd H. E, KNOOPS, Kèvin, ZEVENHOVEN-DOBBE, Jessika C, BEUGELING, Corrine, VAN DER MEER, Yvonne, MIEKE MOMMAAS, A, SNIJDER, Eric J

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The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent by te Velthuis, Aartjan J W, Arnold, Jamie J, Cameron, Craig E, van den Worm, Sjoerd H E, Snijder, Eric J

“…An RNA-dependent RNA polymerase (RdRp) is the central catalytic subunit of the RNA-synthesizing machinery of all positive-strand RNA viruses. Usually, RdRp…”
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New Structure Model for the Packaging Signal in the Genome of Group IIa Coronaviruses by CHEN, Shih-Cheng, VAN DEN BORN, Erwin, VAN DEN WORM, Sjoerd H. E, PLEIJ, Cornelis W. A, SNIJDER, Eric J, OLSTHOORN, René C. L

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Integrity of the Early Secretory Pathway Promotes, but Is Not Required for, Severe Acute Respiratory Syndrome Coronavirus RNA Synthesis and Virus-Induced Remodeling of Endoplasmic Reticulum Membranes by Knoops, Kèvin, Swett-Tapia, Cindy, van den Worm, Sjoerd H E, Te Velthuis, Aartjan J W, Koster, Abraham J, Mommaas, A Mieke, Snijder, Eric J, Kikkert, Marjolein

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Apocynin inhibits peroxynitrite formation by murine macrophages by Muijsers, R B R, Van Den Worm, E, Folkerts, G, Beukelman, C J, Koster, A S, Postma, D S, Nijkamp, F P

“…Peroxynitrite (ONOO−) the highly reactive coupling product of nitric oxide and superoxide, has been implicated in the pathogenesis of an increasing number of…”
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The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension by te Velthuis, Aartjan J.W., van den Worm, Sjoerd H. E., Snijder, Eric J.

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The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension by te Velthuis, Aartjan J W, van den Worm, Sjoerd H E, Snijder, Eric J

“…Uniquely among RNA viruses, replication of the ~30-kb SARS-coronavirus genome is believed to involve two RNA-dependent RNA polymerase (RdRp) activities. The…”
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Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture by te Velthuis, Aartjan J W, van den Worm, Sjoerd H E, Sims, Amy C, Baric, Ralph S, Snijder, Eric J, van Hemert, Martijn J

“…Increasing the intracellular Zn(2+) concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses,…”
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An in vitro examination of the antioxidant and anti-inflammatory properties of buckwheat honey by van den Berg, A.J.J., van den Worm, E., Quarles van Ufford, H.C., Halkes, S.B.A., Hoekstra, M.J., Beukelman, C.J.

“…Objective: Hydroxyl radical and hypochlorite anion formed at the wound site from superoxide anion produced by activated polymorphonuclear neutrophils (PMNs)…”
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Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture by te Velthuis, Aartjan J. W., van den Worm, Sjoerd H. E., Sims, Amy C., Baric, Ralph S., Snijder, Eric J., van Hemert, Martijn J.

“…Increasing the intracellular Zn2+ concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses,…”
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Nucleotide sequence of a ssRNA phage from Acinetobacter: kinship to coliphages by Klovins, J, Overbeek, G. P, van den Worm, S. H. E, Ackermann, H.-W, van Duin, J

“…Department of Biochemistry, Gorlaeus Laboratories, Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands 1 Biomedical Research Centre, University of…”
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Nerve growth factor and the vanilloid receptor: partners in crime? by Van Den Worm, E., Nijkamp, F. P., Engels, F.

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Immunomodulatory and anti-inflammatory activity of Picrorhiza scrophulariiflora by Smit, H.F, Kroes, B.H, van den Berg, A.J.J, van der Wal, D, van den Worm, E, Beukelman, C.J, van Dijk, H, Labadie, R.P

“…Extracts of the rhizomes of Picrorhiza scrophulariiflora Pennell (Scrophulariaceae) were investigated for their in vitro and in vivo immunomodulatory…”
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Group 2 coronaviruses prevent immediate early interferon induction by protection of viral RNA from host cell recognition by Versteeg, Gijs A, Bredenbeek, Peter J, van den Worm, Sjoerd H.E, Spaan, Willy J.M

“…Abstract Many viruses encode antagonists to prevent interferon (IFN) induction. Infection of fibroblasts with the murine hepatitis coronavirus (MHV) and…”
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Apocynin, a plant-derived, cartilage-saving drug, might be useful in the treatment of rheumatoid arthritis by Lafeber, F. P. J. G., Beukelman, C. J., van den Worm, E., van Roy, J. L. A. M., Vianen, M. E., van Roon, J. A. G., van Dijk, H., Bijlsma, J. W. J.

“…Objective. To investigate whether apocynin, 1-(4-hydroxy-3-methoxyphenyl)ethanone, is able to diminish inflammation-induced cartilage destruction in rheumatoid…”
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Base complementarity in helix 2 of the central pseudoknot in 16S rRNA is essential for ribosome functioning by Poot, Raymond A., van den Worm, Sjoerd H. E., Pleij, Cornelis W. A., van Duin, Jan

“…Helix 2 of the central pseudoknot structure in Escherichia coli 16S rRNA is formed by a long-distance interaction between nt 17–19 and 918–916, resulting in…”
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Role of lipoxygenase products in the effects of angiotensin II in the isolated aorta and perfused heart of the rat by Dam, J P, Worm, E, Vleeming, W, Post, M J, Porsius, A J, Wemer, J

“…THE objective of this study was to determine whether arachidonate metabolites are involved in the vasoconstrictive effects of angiotensin II in rats. In the…”
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