Search Results - "van den Neste, E"

Outcomes of diffuse large B-cell lymphoma patients relapsing after autologous stem cell transplantation: an analysis of patients included in the CORAL study by Van Den Neste, E, Schmitz, N, Mounier, N, Gill, D, Linch, D, Trneny, M, Bouadballah, R, Radford, J, Bargetzi, M, Ribrag, V, Dührsen, U, Ma, D, Briere, J, Thieblemont, C, Bachy, E, Moskowitz, C H, Glass, B, Gisselbrecht, C

“…In the CORAL study, 255 chemosensitive relapses with diffuse large B-cell lymphoma (DLBCL) were consolidated with autologous stem cell transplantation (ASCT),…”
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Outcome of patients with relapsed diffuse large B-cell lymphoma who fail second-line salvage regimens in the International CORAL study by Van Den Neste, E, Schmitz, N, Mounier, N, Gill, D, Linch, D, Trneny, M, Milpied, N, Radford, J, Ketterer, N, Shpilberg, O, Dührsen, U, Ma, D, Brière, J, Thieblemont, C, Salles, G, Moskowitz, C H, Glass, B, Gisselbrecht, C

“…Salvage chemotherapy followed by autologous stem cell transplantation (ASCT) is the standard second-line treatment for relapsed and refractory diffuse large…”
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Adult haemophagocytic lymphohistiocytosis: a review by Yildiz, H, Van Den Neste, E, P. Defour, J, Danse, E, Yombi, J.C

“…Abstract Haemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder characterized by hyperimmune response. The mortality is high despite progress…”
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Chromosomal translocations independently predict treatment failure, treatment-free survival and overall survival in B-cell chronic lymphocytic leukemia patients treated with cladribine by VAN DEN NESTE, E, ROBIN, V, FERRANT, A, ROBERT, A, MICHAUX, L, FRANCART, J, HAGEMEIJER, A, SLUT, M, VANDENBERGHE, P, DELANNOY, A, SONET, A, DENEYS, V, COSTANTINI, S

“…Chromosomal translocations represent an important prognostic indicator in B-cell chronic lymphocytic leukemia (B-CLL). However, their value had been neither…”
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Translocation t(14;18) is not associated with inferior outcome in chronic lymphocytic leukemia by Put, N, Meeus, P, Chatelain, B, Rack, K, Boeckx, N, Nollet, F, Graux, C, Van Den Neste, E, Janssens, A, Madoe, V, Van Hoof, A, Bilhou-Nabera, C, Wlodarska, I, Vandenberghe, P, Michaux, L

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Inhibition of RNA transcription : a biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine by HUANG, P, SANDOVAL, A, VAN DEN NESTE, E, KEATING, M. J, PLUNKETT, W

“…Fludarabine is a nucleotide analog effective in the clinical treatment of chronic lymphocytic leukemia (CLL) and other indolent lymphocytic malignancies…”
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Transient hypophysitis in a patient treated by duvelisib for chronic lymphocytic leukemia by Orioli, Laura, Sarti, K., Van Den Neste, E., Maiter, D.

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VERY LONG‐TERM FOLLOW‐UP OF RITUXIMAB MAINTENANCE IN YOUNG PATIENTS WITH MANTLE CELL LYMPHOMA INCLUDED IN THE LYMA TRIAL, A LYSA STUDY by Sarkozy, C., Thieblemont, C., Oberic, L., Moreau, A., Bouabdallah, K., Damaj, G., Gastine, T., Ribrag, V., Casasnovas, O., Haioun, C., Houot, R., Jardin, F., Neste, E., Cheminant, M., Morschhauser, F., Callana, M., Ghesquieres, H., Gressin, R., Hermine, O., Le Gouill, S.

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R‐CODOX‐M/R‐IVAC VERSUS DA‐EPOCH‐R IN PATIENTS WITH NEWLY DIAGNOSED HIGH‐RISK BURKITT LYMPHOMA: FINAL RESULTS OF A MULTI‐CENTER RANDOMIZED HOVON/SAKK TRIAL by Chamuleau, M., Stenner, F., Chitu, D., Novak, U., Minnema, M., Visser, O., Stevens, W., Zenz, T., Imhoff, G., Wu, K., Demandt, A., Kersten, M. J., Terpstra, W., Tick, L., Deeren, D., Neste, E., Gregor, M., Veelken, H., Bohmer, L., Casper, C., Dirnhofer, S., Brand, M., Jong, D., Nijland, M., Lugtenburg, P.

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Phase I/II study of 2-chloro-2'-deoxyadenosine with cyclophosphamide in patients with pretreated B cell chronic lymphocytic leukemia and indolent non-Hodgkin's lymphoma by VAN DEN NESTE, E, LOUVIAUX, I, STRAETMANS, N, COCHE, E, VENET, C, DUPREZ, T, FERRANT, A, MICHAUX, J. L, DELANNOY, A, MICHAUX, L, SONET, A, BOSLY, A, DOYEN, C, MINEUR, P, ANDRE, M

“…Because of their substantial in vitro synergy, we conducted a dose-escalation study of cyclophosphamide (CP) added to 2-chloro-2'-deoxyadenosine (CdA) in…”
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Long-term follow-up of an age-adapted C5R protocol followed by radiotherapy in 99 newly diagnosed primary CNS lymphomas: a prospective multicentric phase II study of the Groupe d’Etude des Lymphomes de l’Adulte (GELA) by Ghesquières, H., Ferlay, C., Sebban, C., Perol, D., Bosly, A., Casasnovas, O., Reman, O., Coiffier, B., Tilly, H., Morel, P., Van den Neste, E., Colin, P., Haioun, C., Biron, P., Blay, J.-Y.

“…This prospective multicentric phase II study aimed to confirm the results of the C5R protocol of high-dose methotrexate (MTX)-based chemotherapy (CT) for…”
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Identification of Phosphorylation Sites on Human Deoxycytidine Kinase After Overexpression in Eucaryotic Cells by Smal, C., Vertommen, D., Bertrand, L., Rider, M. H., Van Den Neste, E., Bontemps, F.

“…Compelling evidence suggests that deoxycytidine kinase (dCK), a key enzyme in the salvage of deoxyribonucleosides and in the activation of clinically relevant…”
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499 Phase 2a study of copanlisib, a novel phosphatidylinositol-3-kinase (PI3K) inhibitor, in patients with relapsed/refractory, indolent or aggressive lymphoma by Dreyling, M, Zinzani, P.L, Bouabdallah, K, Bron, D, Cunningham, D, Linton, K, Thieblemont, C, van den Neste, E, Vitolo, U, Grunert, J, Giurescu, M, Mappa, S, Childs, B.H, Morschhauser, F

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A PHASE 2B STUDY OF SELINEXOR IN PATIENTS WITH RELAPSED/REFRACTORY (R/R) DIFFUSE LARGE B‐CELL LYMPHOMA (DLBCL) by Kalakonda, N., Cavallo, F., Follows, G., Goy, A., Vermaat, J., Casasnovas, O., Lavee, O., Maerevoet, M., Zijlstra, J., Bakshi, S., Bouabdallah, R., Choquet, S., Gurion, R., Hill, B., Jaeger, U., Sancho, J., Schuster, M., Thieblemont, C., De la Cruz, F., Egyed, M., Mishra, S., Offner, F., Vassilakopoulos, T., Warzocha, K., Oluyadi, A., McCarthy, D., Ma, X., Corona, K., Shah, J., Van Den Neste, E., Canales, M.

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Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymphocytic leukemia cell lines by Bastin-Coyette, L., Cardoen, S., Smal, C., de Viron, E., Arts, A., Amsailale, R., Van Den Neste, E., Bontemps, F.

“…2-Chorodeoxyadenosirne (CdA) down-regulates p21 despite p53 activation in CLL cell lines. Cdk2 activation and PCNA monoubiquitination, which are known to be…”
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Potentiation of antitumor effects of cyclophosphamide derivatives in B-chronic lymphocytic leukemia cells by 2-chloro-2'-deoxyadenosine by VAN DEN NESTE, E, BONTEMPS, F, VAN DEN BERGHE, G, DELACAUW, A, CARDOEN, S, LOUVIAUX, I, SCHEIFF, J. M, GILLIS, E, LEVEUGLE, P, DENEYS, V, FERRANT, A

“…Because 2-chloro-2'-deoxyadenosine (CdA) is active in B-chronic lymphocytic leukemia (B-CLL), and may interfere with DNA repair, we investigated the…”
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A PHASE II LYSA STUDY OF OBINUTUZUMAB COMBINED WITH LENALIDOMIDE FOR RELAPSED OR REFRACTORY FOLLICULAR B‐CELL LYMPHOMA by Morschhauser, F., Le Gouill, S., Feugier, P., Van Den Neste, E., Nicolas‐Virelizier, E., Bijou, F., Salles, G.A., Tilly, H., Van Eygen, K., Van Hoof, A., Bonnet, C., Haioun, C., Bouabdallah, R., Fabiani, B., Xerri, L., Cartron, G., Houot, R.

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Rituximab maintenance after autologous stem‐cell transplantation in patients with mantle cell lymphoma, final result of the LyMA trial conducted on behalf the LYSA group by Le Gouill, S., Thieblemont, C., Oberic, L., Moreau, A., Bouabdallah, K., Dartigeas, C., Damaj, G., Gastinne, T., Ribrag, V., Feugier, P., Casasnovas, O., Zerazhi, H., Haioun, C., Maisonneuve, H., Van Den Neste, E., Tournilhac, O., Le Dû, K., Morschhauser, F., Cartron, G., Fornecker, L., Salles, G., Tilly, H., Lamy, T., Gressin, R., Hermine, O.

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Influence of Phosphorylation of THR-3, SER-11, and SER-15 on Deoxycytidine Kinase Activity and Stability by Smal, C., Ntamashimikiro, S., Arts, A., Van Den Neste, E., Bontemps, F.

“…Deoxycytidine kinase (dCK) is a key enzyme in the salvage of deoxyribonucleosides and in the activation of several anticancer and antiviral nucleoside…”
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Remission of severe cold agglutinin disease after Rituximab therapy by LAYIOS, N, VAN DEN NESTE, E, JOST, E, DENEYS, V, SCHEIFF, J. M, FERRANT, A

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