Search Results - "van den Maagdenberg, A"

Distinguishing core from penumbra by lipid profiles using Mass Spectrometry Imaging in a transgenic mouse model of ischemic stroke by Mulder, I. A., Ogrinc Potočnik, N., Broos, L. A. M., Prop, A., Wermer, M. J. H., Heeren, R. M. A., van den Maagdenberg, A. M. J. M.

“…Detecting different lipid profiles in early infarct development may give an insight on the fate of compromised tissue. Here we used Mass Spectrometry Imaging…”
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MEA-ToolBox: an Open Source Toolbox for Standardized Analysis of Multi-Electrode Array Data by Hu, Michel, Frega, Monica, Tolner, Else A., van den Maagdenberg, A. M. J. M., Frimat, J. P., le Feber, Joost

“…Functional assessment of in vitro neuronal networks—of relevance for disease modelling and drug testing—can be performed using multi-electrode array (MEA)…”
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Systemic features of retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations: a monogenic small vessel disease by Pelzer, N., Hoogeveen, E. S., Haan, J., Bunnik, R., Poot, C. C., van Zwet, E. W., Inderson, A., Fogteloo, A. J., Reinders, M. E. J., Middelkoop, H. A. M., Kruit, M. C., van den Maagdenberg, A. M. J. M., Ferrari, M. D., Terwindt, G. M.

“…Background Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL‐S) is a small vessel disease caused by C‐terminal…”
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Early seizures and cerebral oedema after trivial head trauma associated with the CACNA1A S218L mutation by Stam, A H, Luijckx, G-J, Poll-Thé, B T, Ginjaar, I B, Frants, R R, Haan, J, Ferrari, M D, Terwindt, G M, van den Maagdenberg, A M J M

“…Objective:To study the clinical spectrum of CACNA1A S218L mutation carriers with special attention to “early seizures and cerebral oedema after trivial head…”
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Shared genetic factors in migraine and depression: Evidence from a genetic isolate by STAM, A. H, DE VRIES, B, VAN DUIJN, C. M, TERWINDT, G. M, JANSSENS, A. C. J. W, VANMOLKOT, K. R. J, AULCHENKO, Y. S, HENNEMAN, P, OOSTRA, B. A, FRANTS, R. R, VAN DEN MAAGDENBERG, A. M. J. M, FERRARI, M. D

“…To investigate the co-occurrence of migraine and depression and assess whether shared genetic factors may underlie both diseases. Subjects were 2,652…”
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Animal models of migraine: looking at the component parts of a complex disorder by Bergerot, A., Holland, P. R., Akerman, S., Bartsch, T., Ahn, A. H., MaassenVanDenBrink, A., Reuter, U., Tassorelli, C., Schoenen, J., Mitsikostas, D. D., Van Den Maagdenberg, A. M. J. M., Goadsby, P. J.

“…Animal models of human disease have been extremely helpful both in advancing the understanding of brain disorders and in developing new therapeutic approaches…”
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Systematic analysis of three FHM genes in 39 sporadic patients with hemiplegic migraine by DE VRIES, B, FREILINGER, T, HAAN, J, PUSCH, M, VAN DEN MAAGDENBERG, A. M. J. M, FERRARI, M. D, DICHGANS, M, VANMOLKOT, K. R. J, KOENDERINK, J. B, STAM, A. H, TERWINDT, G. M, BABINI, E, VAN DEN BOOGERD, E. H, VAN DEN HEUVEL, J. J. M. W, FRANTS, R. R

“…Familial (FHM) and sporadic (SHM) hemiplegic migraine are severe subtypes of migraine associated with transient hemiparesis. For FHM, three genes have been…”
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Correction to: Migraine-relevant sex-dependent activation of mouse meningeal afferents by TRPM3 agonists by Krivoshein, G., Tolner, E. A., van den Maagdenberg, A. M. J. M., Giniatullin, R. A.

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Heterozygous TREX1 mutations in early-onset cerebrovascular disease by Pelzer, N., de Vries, B., Boon, E. M. J., Kruit, M. C., Haan, J., Ferrari, M. D., van den Maagdenberg, A. M. J. M., Terwindt, G. M.

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Childhood epilepsy, familial hemiplegic migraine, cerebellar ataxia, and a new CACNA1A mutation by KORS, E. E, MELBERG, A, VAN DEN MAAGDENBERG, A. M. J. M, VANMOLKOT, K. R. J, KUMLIEN, E, HAAN, J, RAININKO, R, FLINK, R, GINJAAR, H. B, FRONTS, R. R, FERRARI, M. D

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Severe episodic neurological deficits and permanent mental retardation in a child with a novel FHM2 ATP1A2 mutation by Vanmolkot, K. R. J., Stroink, H., Koenderink, J. B., Kors, E. E., van den Heuvel, J. J. M. W., van den Boogerd, E. H., Stam, A. H., Haan, J., De Vries, B. B. A., Terwindt, G. M., Frants, R. R., Ferrari, M. D., van den Maagdenberg, A. M. J. M.

“…Objective Attacks of familial hemiplegic migraine (FHM) are usually associated with transient, completely reversible symptoms. Here, we studied the ATP1A2 FHM2…”
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A hyperexcitability phenotype in mouse trigeminal sensory neurons expressing the R192Q Cacna1a missense mutation of familial hemiplegic migraine type-1 by Hullugundi, S.K, Ansuini, A, Ferrari, M.D, van den Maagdenberg, A.M.J.M, Nistri, A

“…Highlights • Trigeminal sensory neurons of a genetic migraine mouse model were patch-clamped. • No difference in firing evoked by current pulses vs control was…”
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CACNA1A R1347Q: a frequent recurrent mutation in hemiplegic migraine by Stam, AH, Vanmolkot, KRJ, Kremer, HPH, Gärtner, J, Brown, J, Leshinsky-Silver, E, Gilad, R, Kors, EE, Frankhuizen, WS, Ginjaar, HB, Haan, J, Frants, RR, Ferrari, MD, Van Den Maagdenberg, AMJM, Terwindt, GM

“…Of the 18 missense mutations in the CACNA1A gene, which are associated with familial hemiplegic migraine type 1 (FHM1), only mutations S218L, R583Q and T666M…”
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Trigeminal ganglion neuron subtype‐specific alterations of CaV2.1 calcium current and excitability in a Cacna1a mouse model of migraine by Fioretti, B., Catacuzzeno, L., Sforna, L., Gerke‐Duncan, M. B., van den Maagdenberg, A. M. J. M., Franciolini, F., Connor, M., Pietrobon, D.

“…Non‐technical summary  Activation of trigeminal neurons innervating the meninges and release of proinflammatory peptides (in particular calcitonin gene‐related…”
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TREX1 gene variant in neuropsychiatric systemic lupus erythematosus by de Vries, B, Steup-Beekman, G M, Haan, J, Bollen, E L, Luyendijk, J, Frants, R R, Terwindt, G M, van Buchem, M A, Huizinga, T W J, van den Maagdenberg, A M J M, Ferrari, M D

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A novel missense ATP1A2 mutation in a Finnish family with familial hemiplegic migraine type 2 by KAUNISTO, M. A, HARNO, H, FÄRKKILÄ, M, PALOTIE, A, WESSMAN, M, VANMOLKOT, K. R. J, GARGUS, J. J, SUN, G, HÄMÄLÄINEN, E, LIUKKONEN, E, KALLELA, M, VAN DEN MAAGDENBERG, A. M. J. M, FRANTS, R. R

“…Familial hemiplegic migraine (FHM), a rare autosomal dominant subtype of migraine with aura, has been linked to two chromosomal loci, 19p13 and 1q23. Mutations…”
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Migraine and genetic and acquired vasculopathies by Stam, A H, Haan, J, van den Maagdenberg, A M J M, Ferrari, M D, Terwindt, G M

“…It is remarkable that migraine is a prominent part of the phenotype of several genetic vasculopathies, including cerebral autosomal dominant arteriopathy with…”
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Alternating hemiplegia of childhood: no mutations in the glutamate transporter EAAT1 by de Vries, B, Haan, J, Stam, A H, Vanmolkot, K R J, Stroink, H, Laan, L A E M, Gill, D S, Pascual, J, Frants, R R, van den Maagdenberg, A M J M, Ferrari, M D

“…Alternating hemiplegia of childhood (AHC) is a severe brain disorder, mainly characterised by episodes of hemiplegia, progressive mental retardation, and other…”
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A review of the genetic relation between migraine and epilepsy by Haan, J, Terwindt, G M, van den Maagdenberg, A M J M, Stam, A H, Ferrari, M D

“…A possible relation between migraine and epilepsy has been a matter of debate for many decades. Clinical, epidemiological and therapeutic similarities may be…”
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Intravital microscopy on a closed cranial window in mice: a model to study trigeminovascular mechanisms involved in migraine by Gupta, S, Akerman, S, van den Maagdenberg, A M J M, Saxena, P R, Goadsby, P J, van den Brink, A M

“…The purpose of the study was to develop a mouse model to study trigeminovascular mechanisms using intravital microscopy on a closed cranial window. In…”
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