Search Results - "van den Heuvel, Robert H.H."

The Active Conformation of Glutamate Synthase and its Binding to Ferredoxin by van den Heuvel, Robert H.H, Svergun, Dmitri I, Petoukhov, Maxim V, Coda, Alessandro, Curti, Bruno, Ravasio, Sergio, Vanoni, Maria A, Mattevi, Andrea

“…Glutamate synthases (GltS) are crucial enzymes in ammonia assimilation in plants and bacteria, where they catalyze the formation of two molecules of…”
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Interactions of Kid-Kis toxin-antitoxin complexes with the parD operator-promoter region of plasmid R1 are piloted by the Kis antitoxin and tuned by the stoichiometry of Kid-Kis oligomers by Monti, Maria C, Hernández-Arriaga, Ana M, Kamphuis, Monique B, López-Villarejo, Juan, Heck, Albert J.R, Boelens, Rolf, Díaz-Orejas, Ramón, van den Heuvel, Robert H.H

“…The parD operon of Escherichia coli plasmid R1 encodes a toxin-antitoxin system, which is involved in plasmid stabilization. The toxin Kid inhibits cell growth…”
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Crystal Structure and Biochemical Properties of a Novel Thermostable Esterase Containing an Immunoglobulin-Like Domain by Levisson, Mark, Sun, Lei, Hendriks, Sjon, Swinkels, Peter, Akveld, Twan, Bultema, Jelle B., Barendregt, Arjan, van den Heuvel, Robert H.H., Dijkstra, Bauke W., van der Oost, John, Kengen, Servé W.M.

“…Comparative analysis of the genome of the hyperthermophilic bacterium Thermotoga maritima revealed a hypothetical protein (EstA) with typical esterase…”
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Microsomal glutathione transferase 1 exhibits one-third-of-the-sites-reactivity towards glutathione by Ålander, Johan, Lengqvist, Johan, Holm, Peter J., Svensson, Richard, Gerbaux, Pascal, Heuvel, Robert H.H. van den, Hebert, Hans, Griffiths, William J., Armstrong, Richard N., Morgenstern, Ralf

“…The trimeric membrane protein microsomal glutathione transferase 1 (MGST1) possesses glutathione transferase and peroxidase activity. Previous data indicated…”
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Probing Genuine Strong Interactions and Post-translational Modifications in the Heterogeneous Yeast Exosome Protein Complex by Synowsky, Silvia A, van den Heuvel, Robert H H, Mohammed, Shabaz, Pijnappel, Pim W W M, Heck, Albert J R

“…The characterization of heterogeneous multicomponent protein complexes, which goes beyond identification of protein subunits, is a challenging task. Here we…”
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Structural Studies on the Synchronization of Catalytic Centers in Glutamate Synthase by van den Heuvel, Robert H.H., Ferrari, Davide, Bossi, Roberto T., Ravasio, Sergio, Curti, Bruno, Vanoni, Maria A., Florencio, Francisco J., Mattevi, Andrea

“…The complex iron-sulfur flavoprotein glutamate synthase (GltS) plays a prominent role in ammonia assimilation in bacteria, yeasts, and plants. GltS catalyzes…”
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CprK Crystal Structures Reveal Mechanism for Transcriptional Control of Halorespiration by Joyce, M. Gordon, Levy, Colin, Gábor, Krisztina, Pop, Stelian M., Biehl, Benjamin D., Doukov, Tzanko I., Ryter, Jodi M., Mazon, Hortense, Smidt, Hauke, van den Heuvel, Robert H.H., Ragsdale, Stephen W., van der Oost, John, Leys, David

“…Halorespiration is a bacterial respiratory process in which haloorganic compounds act as terminal electron acceptors. This process is controlled at…”
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ADP Competes with FAD Binding in Putrescine Oxidase by van Hellemond, Erik W., Mazon, Hortense, Heck, Albert J., van den Heuvel, Robert H.H., Heuts, Dominic P.H.M., Janssen, Dick B., Fraaije, Marco W.

“…Putrescine oxidase from Rhodococcus erythropolis NCIMB 11540 (PuORh) is a soluble homodimeric flavoprotein of 100 kDa, which catalyzes the oxidative…”
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Transcriptional Activation by CprK1 Is Regulated by Protein Structural Changes Induced by Effector Binding and Redox State by Mazon, Hortense, Gábor, Krisztina, Leys, David, Heck, Albert J.R., van der Oost, John, van den Heuvel, Robert H.H.

“…The transcriptional activator CprK1 from Desulfitobacterium-hafniense, a member of the ubiquitous cAMP receptor protein/fumarate nitrate reduction regulatory…”
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Quaternary Structure of Azospirillum brasilense NADPH-dependent Glutamate Synthase in Solution as Revealed by Synchrotron Radiation X-ray Scattering by Petoukhov, Maxim V., Svergun, Dmitri I., Konarev, Peter V., Ravasio, Sergio, van den Heuvel, Robert H.H., Curti, Bruno, Vanoni, Maria A.

“…Azospirillum brasilense glutamate synthase (GltS) is the prototype of bacterial NADPH-dependent enzymes, a class of complex iron-sulfur flavoproteins essential…”
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Asp-170 Is Crucial for the Redox Properties of Vanillyl-alcohol Oxidase by van den Heuvel, Robert H.H., Fraaije, Marco W., Mattevi, Andrea, van Berkel, Willem J.H.

“…Vanillyl-alcohol oxidase is a flavoprotein containing a covalent flavin that catalyzes the oxidation of 4-(methoxymethyl)phenol to 4-hydroxybenzaldehyde. The…”
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Identification of the Missing Links in Prokaryotic Pentose Oxidation Pathways by Brouns, Stan J.J., Walther, Jasper, Snijders, Ambrosius P.L., van de Werken, Harmen J.G., Willemen, Hanneke L.D.M., Worm, Petra, de Vos, Marjon G.J., Andersson, Anders, Lundgren, Magnus, Mazon, Hortense F.M., van den Heuvel, Robert H.H., Nilsson, Peter, Salmon, Laurent, de Vos, Willem M., Wright, Phillip C., Bernander, Rolf, van der Oost, John

“…The pentose metabolism of Archaea is largely unknown. Here, we have employed an integrated genomics approach including DNA microarray and proteomics analyses…”
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Crystal structure of E.coli alcohol dehydrogenase YqhD: evidence of a covalently modified NADP coenzyme by Sulzenbacher, Gerlind, Alvarez, Karine, Van Den Heuvel, Robert H H, Versluis, Cees, Spinelli, Silvia, Campanacci, Valérie, Valencia, Christel, Cambillau, Christian, Eklund, Hans, Tegoni, Mariella

“…In the course of a structural genomics program aiming at solving the structures of Escherichia coli open reading frame (ORF) products of unknown function, we…”
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Redox properties of vanillyl-alcohol oxidase by van den Heuvel, Robert H H, Fraaije, Marco W, van Berkel, Willem J H

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Tuning of the product spectrum of vanillyl-alcohol oxidase by medium engineering by van den Heuvel, Robert H.H, Partridge, Johann, Laane, Colja, Halling, Peter J, van Berkel, Willem J.H

“…The flavoenzyme vanillyl-alcohol oxidase (VAO) catalyzes the conversion of 4-alkylphenols through the initial formation of p-quinone methide intermediates…”
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Covalent flavinylation enhances the oxidative power of vanillyl-alcohol oxidase by Fraaije, Marco W, van den Heuvel, Robert H.H, Mattevi, Andrea, van Berkel, Willem J.H

“…Vanillyl-alcohol oxidase (VAO) from Penicillium simplicissimum is an inducible flavoprotein that is active with a wide range of phenolic compounds. The enzyme…”
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Investigation of intact protein complexes by mass spectrometry by Heck, Albert J. R., van den Heuvel, Robert H. H.

“…I. Introduction 00   II. Electrospray Ionization of Biomacromolecules 00   III. Mass Analyzers for Biomacromolecular Mass Spectrometry 00 A.  Collisional…”
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Native protein mass spectrometry: from intact oligomers to functional machineries by Heuvel, Robert HH van den, Heck, Albert JR

“…The development of electrospray ionization coupled to mass spectrometry has enabled the analysis of very large intact protein complexes, even when they are…”
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Improving the Performance of a Quadrupole Time-of-Flight Instrument for Macromolecular Mass Spectrometry by van den Heuvel, Robert H. H., van Duijn, Esther, Mazon, Hortense, Synowsky, Silvia A., Lorenzen, Kristina, Versluis, Cees, Brouns, Stan J. J., Langridge, Dave, van der Oost, John, Hoyes, John, Heck, Albert J. R.

“…We modified and optimized a first generation quadrupole time-of-flight (Q-TOF) 1 to perform tandem mass spectrometry on macromolecular protein complexes. The…”
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Structure, function and redesign of vanillyl-alcohol oxidase by van den Heuvel, Robert H.H, Fraaije, Marco W, Mattevi, Andrea, van Berkel, Willem J.H

“…Vanillyl-alcohol oxidase (VAO) from Penicillium simplicissimum is an inducible flavoprotein involved in the biodegradation of lignin-derived aromatic…”
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