Search Results - "van den Handel, Kim"
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The potential of PARP as a therapeutic target across pediatric solid malignancies
Published in BMC cancer (05-04-2023)“…Pediatric cancer is the leading cause of disease-related death in children and the need for better therapeutic options remains urgent. Due to the limited…”
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Cellular enlargement - A new hallmark of aging?
Published in Frontiers in cell and developmental biology (10-11-2022)“…Years of important research has revealed that cells heavily invest in regulating their size. Nevertheless, it has remained unclear why accurate size control is…”
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Journal Article -
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Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma
Published in Frontiers in oncology (27-09-2022)“…Neuroblastoma is the most common extracranial solid tumor found in children and despite intense multi-modal therapeutic approaches, low overall survival rates…”
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Journal Article