Search Results - "van den Brink, Susanne C"

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  1. 1

    An in vitro model of early anteroposterior organization during human development by Moris, Naomi, Anlas, Kerim, van den Brink, Susanne C., Alemany, Anna, Schröder, Julia, Ghimire, Sabitri, Balayo, Tina, van Oudenaarden, Alexander, Martinez Arias, Alfonso

    Published in Nature (London) (18-06-2020)
    “…The body plan of the mammalian embryo is shaped through the process of gastrulation, an early developmental event that transforms an isotropic group of cells…”
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  2. 2

    Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process by Tessadori, Federico, Tsingos, Erika, Colizzi, Enrico Sandro, Kruse, Fabian, van den Brink, Susanne C, van den Boogaard, Malou, Christoffels, Vincent M, Merks, Roeland MH, Bakkers, Jeroen

    Published in eLife (10-08-2021)
    “…Organ laterality refers to the left-right asymmetry in disposition and conformation of internal organs and is established during embryogenesis. The heart is…”
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  3. 3

    Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids by van den Brink, Susanne C., Alemany, Anna, van Batenburg, Vincent, Moris, Naomi, Blotenburg, Marloes, Vivié, Judith, Baillie-Johnson, Peter, Nichols, Jennifer, Sonnen, Katharina F., Martinez Arias, Alfonso, van Oudenaarden, Alexander

    Published in Nature (London) (18-06-2020)
    “…Gastruloids are three-dimensional aggregates of embryonic stem cells that display key features of mammalian development after implantation, including…”
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  4. 4

    3D gastruloids: a novel frontier in stem cell-based in vitro modeling of mammalian gastrulation by van den Brink, Susanne C., van Oudenaarden, Alexander

    Published in Trends in cell biology (01-09-2021)
    “…3D gastruloids, aggregates of embryonic stem cells that recapitulate key aspects of gastrula-stage embryos, have emerged as a powerful tool to study the early…”
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    Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells by van den Brink, Susanne C, Baillie-Johnson, Peter, Balayo, Tina, Hadjantonakis, Anna-Katerina, Nowotschin, Sonja, Turner, David A, Martinez Arias, Alfonso

    Published in Development (Cambridge) (01-11-2014)
    “…Mouse embryonic stem cells (mESCs) are clonal populations derived from preimplantation mouse embryos that can be propagated in vitro and, when placed into…”
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  7. 7

    Modelling human embryogenesis: embryo-like structures spark ethical and policy debate by Pereira Daoud, Ana M, Popovic, Mina, Dondorp, Wybo J, Trani Bustos, Marc, Bredenoord, Annelien L, Chuva de Sousa Lopes, Susana M, van den Brink, Susanne C, Roelen, Bernard A J, de Wert, Guido M W R, Heindryckx, Björn

    Published in Human reproduction update (01-11-2020)
    “…Studying the human peri-implantation period remains hindered by the limited accessibility of the in vivo environment and scarcity of research material. As…”
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  8. 8

    Haematopoietic development and HSC formation in vitro: promise and limitations of gastruloid models by Dijkhuis, Liza, Johns, Ayona, Ragusa, Denise, van den Brink, Susanne C, Pina, Cristina

    Published in Emerging topics in life sciences (18-12-2023)
    “…Haematopoietic stem cells (HSCs) are the most extensively studied adult stem cells. Yet, six decades after their first description, reproducible and…”
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